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Associations of the...
Associations of the EAT-Lancet reference diet with metabolic dysfunction-associated steatotic liver disease and its severity : a multi-cohort study
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- Zhang, Shunming (författare)
- Xi'an Jiaotong University Health Science Center
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- Yan, Yan (författare)
- Sun Yat-sen University
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- Zeng, Xu-Fen (författare)
- The First Affiliated Hospital of Wenzhou Medical University, Wenzhou
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- Gu, Yeqing (författare)
- Institute of Radiation Medicine, Chinese Academy of Medical Sciences
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- Wu, Hongmei (författare)
- School of Public Health of Tianjin University of Traditional Chinese Medicine,Tianjin Medical University
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- Zhang, Qing (författare)
- Tianjin Medical University General Hospital
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- Liu, Li (författare)
- Tianjin Medical University General Hospital
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- Huo, Zhenyu (författare)
- North China University of Science and Technology (NCUST)
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- Luo, Xiaoqin (författare)
- Xi'an Jiaotong University Health Science Center
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- Zhang, Rui (författare)
- The First Affiliated Hospital of Wenzhou Medical University, Wenzhou
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- Sonestedt, Emily (författare)
- Lund University,Lunds universitet,Nutritionsepidemiologi,Forskargrupper vid Lunds universitet,Nutrition Epidemiology,Lund University Research Groups
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- Borné, Yan (författare)
- Lund University,Lunds universitet,Nutritionsepidemiologi,Forskargrupper vid Lunds universitet,Nutrition Epidemiology,Lund University Research Groups
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- Qi, Lu (författare)
- Harvard T.H. Chan School of Public Health,Tulane University
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- Huang, Tao (författare)
- Peking University
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- Zheng, Ming-Hua (författare)
- The First Affiliated Hospital of Wenzhou Medical University, Wenzhou
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- Chen, Yu-Ming (författare)
- Sun Yat-sen University
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- Niu, Kaijun (författare)
- School of Public Health of Tianjin University of Traditional Chinese Medicine,Tianjin Medical University,Tianjin Medical University General Hospital
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- Ma, Le (författare)
- Xi'an Jiaotong University Health Science Center
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(creator_code:org_t)
- Engelska.
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Ingår i: Hepatology. - 1527-3350.
- Relaterad länk:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- BACKGROUND AIMS: The EAT-Lancet Commission devised a globally sustainable dietary pattern to jointly promote human health and sustainability. However, the extent to which this diet supports metabolic dysfunction-associated steatotic liver disease (MASLD) has not yet been assessed. This study aimed to investigate the association between the EAT-Lancet diet and risk of MASLD and its severity.APPROACH RESULTS: This prospective multi-cohort study included 15,263 adults from the Tianjin Chronic Low-grade Systemic Inflammation and Health (TCLSIH) cohort, 1,137 adults from the Guangzhou Nutrition and Health Study (GNHS) cohort, and 175,078 adults from the UK Biobank. Additionally, 228 Chinese adults from the Prospective Epidemic Research Specifically of Non-alcoholic Steatohepatitis (PERSONS) with biopsy-proven MASLD were included. An EAT-Lancet diet index was created to reflect adherence to the EAT-Lancet reference diet. The TCLSIH cohort recorded 3,010 MASLD cases during 53,575 person-years of follow-up, the GNHS cohort documented 624 MASLD cases during 6,454 person-years of follow-up, and the UK Biobank 1,350 developed MASLD cases during 1,745,432 person-years of follow-up. In multivariable models, participants in the highest tertiles of the EAT-Lancet diet index had a lower risk of MASLD compared with those in the lowest tertiles (TCLSIH: HR=0.87, 95% CI: 0.78, 0.96; GNHS: HR=0.79, 95% CI: 0.64, 0.98; UK Biobank: HR=0.73, 95% CI: 0.63, 0.85). Moreover, liver controlled attenuation parameter decreased with increasing the diet index in individuals with biopsy-proven MASLD (β=-5.895; 95% CI: -10.014, -1.775).CONCLUSIONS: Adherence to the EAT-Lancet reference diet was inversely associated with risk of MASLD as well as its severity.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Näringslära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nutrition and Dietetics (hsv//eng)
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Zhang, Shunming
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Yan, Yan
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Zeng, Xu-Fen
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Gu, Yeqing
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Wu, Hongmei
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Zhang, Qing
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Liu, Li
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Huo, Zhenyu
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Luo, Xiaoqin
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Zhang, Rui
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Sonestedt, Emily
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Borné, Yan
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Qi, Lu
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Huang, Tao
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Zheng, Ming-Hua
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Chen, Yu-Ming
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Niu, Kaijun
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Ma, Le
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Hälsovetenskap
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och Näringslära
- Artiklar i publikationen
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Hepatology
- Av lärosätet
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Lunds universitet