Sökning: onr:"swepub:oai:lup.lub.lu.se:ca1bfe81-edb9-4271-a1f5-48322906e4f7" >
Platelet transfusio...
Platelet transfusions and thrombocytopenia in intensive care units : Protocol for an international inception cohort study (PLOT-ICU)
-
- Anthon, Carl Thomas (författare)
- University of Copenhagen
-
- Pène, Frédéric (författare)
- Université Paris Cité
-
- Perner, Anders (författare)
- University of Copenhagen
-
visa fler...
-
- Azoulay, Elie (författare)
- Université Paris Cité
-
- Puxty, Kathryn (författare)
- Glasgow Royal Infirmary
-
- Van De Louw, Andry (författare)
- Pennsylvania State University College of Medicine
-
- Barratt-Due, Andreas (författare)
- Oslo university hospital
-
- Chawla, Sanjay (författare)
- Memorial Sloan-Kettering Cancer Center
-
- Castro, Pedro (författare)
- University of Barcelona
-
- Povoa, Pedro (författare)
- Centro Hospitalar de Lisboa Ocidental (CHLO)
-
- Coelho, Luis (författare)
- Centro Hospitalar de Lisboa Ocidental (CHLO)
-
- Metaxa, Victoria (författare)
- King's College Hospital
-
- Munshi, Laveena (författare)
- Mount Sinai Hospital of University of Toronto
-
- Kochanek, Matthias (författare)
- University of Cologne
-
- Liebregts, Tobias (författare)
- University Hospital Essen
-
- Kander, Thomas (författare)
- Lund University,Lunds universitet,Klinisk forskning inom anestesi och intensivvårdsmedicin,Forskargrupper vid Lunds universitet,Clinical Research in Anaesthesia and Intensive Care Medicine,Lund University Research Groups,Skåne University Hospital
-
- Hästbacka, Johanna (författare)
- University of Helsinki
-
- Møller, Morten Hylander (författare)
- University of Copenhagen
-
- Russell, Lene (författare)
- University of Copenhagen
-
visa färre...
-
(creator_code:org_t)
-
- 2022-08-23
- 2022
- Engelska.
-
Ingår i: Acta Anaesthesiologica Scandinavica. - : Wiley. - 0001-5172 .- 1399-6576. ; 66:9, s. 1146-1155
- Relaterad länk:
-
http://dx.doi.org/10... (free)
-
visa fler...
-
https://lup.lub.lu.s...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- Introduction: Thrombocytopenia is frequent in intensive care unit (ICU) patients and has been associated with worse outcome. Platelet transfusions are often used in the management of ICU patients with severe thrombocytopenia. However, the reported frequencies of thrombocytopenia and platelet transfusion practices in the ICU vary considerably. Therefore, we aim to provide contemporary epidemiological data on thrombocytopenia and platelet transfusion practices in the ICU. Methods: We will conduct an international inception cohort, including at least 1000 acutely admitted adult ICU patients. Routinely available data will be collected at baseline (ICU admission), and daily during ICU stay up to a maximum of 90 days. The primary outcome will be the number of patients with thrombocytopenia (a recorded platelet count < 150 × 109/L) at baseline and/or during ICU stay. Secondary outcomes include mortality, days alive and out of hospital, days alive without life-support, the number of patients with at least one bleeding episode, at least one thromboembolic event and at least one platelet transfusion in the ICU, the number of platelet transfusions and the indications for transfusion. The primary and secondary outcomes will be presented descriptively. In addition, we will assess risk factors for developing thrombocytopenia during ICU stay and the association between thrombocytopenia at baseline and 90-day mortality using logistic regression analyses. Conclusion: The outlined international PLOT-ICU cohort study will provide contemporary epidemiological data on the burden and clinical significance of thrombocytopenia in adult ICU patients and describe the current platelet transfusion practice.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Anestesi och intensivvård (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Anesthesiology and Intensive Care (hsv//eng)
Nyckelord
- intensive care unit
- platelet transfusion
- thrombocytopenia
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Anthon, Carl Tho ...
-
Pène, Frédéric
-
Perner, Anders
-
Azoulay, Elie
-
Puxty, Kathryn
-
Van De Louw, And ...
-
visa fler...
-
Barratt-Due, And ...
-
Chawla, Sanjay
-
Castro, Pedro
-
Povoa, Pedro
-
Coelho, Luis
-
Metaxa, Victoria
-
Munshi, Laveena
-
Kochanek, Matthi ...
-
Liebregts, Tobia ...
-
Kander, Thomas
-
Hästbacka, Johan ...
-
Møller, Morten H ...
-
Russell, Lene
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Anestesi och int ...
- Artiklar i publikationen
-
Acta Anaesthesio ...
- Av lärosätet
-
Lunds universitet