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Healthy Lifestyle a...
Healthy Lifestyle and Mortality Among Adults Receiving Hemodialysis : The DIET-HD Study
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- Su, Guobin (författare)
- Karolinska Institutet,Karolinska Institute,Southern Medical University,Guangdong Provincial Hospital of Traditional Chinese Medicine
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- Saglimbene, Valeria (författare)
- University of Bari Aldo Moro,University of Sydney
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- Wong, Germaine (författare)
- University of Sydney
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- Natale, Patrizia (författare)
- University of Bari Aldo Moro,University of Sydney
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- Ruospo, Marinella (författare)
- University of Bari Aldo Moro
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- Craig, Jonathan C. (författare)
- Flinders University
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- Hegbrant, Jorgen (författare)
- Lund University,Lunds universitet,Njurmedicin,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Nephrology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Carrero, Juan Jesus (författare)
- Karolinska Institutet,Karolinska Institute
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- Strippoli, Giovanni F.M. (författare)
- University of Sydney,University of Bari Aldo Moro
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(creator_code:org_t)
- Elsevier BV, 2022
- 2022
- Engelska.
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Ingår i: American Journal of Kidney Diseases. - : Elsevier BV. - 0272-6386. ; 79:5, s. 688-698
- Relaterad länk:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Rationale & Objective: A healthy lifestyle promotes cardiovascular health and reduces cardiac-related mortality in the general population, but its benefits for people receiving maintenance hemodialysis are uncertain. Study Design: Prospective cohort study. Setting & Participants: 5,483 of 9,757 consecutive adults receiving maintenance hemodialysis (January 2014 to June 2017, median dialysis vintage: 3.6 years) in a multinational private dialysis network and with complete lifestyle data. Exposure: Based on the American Heart Association's recommendations for cardiovascular prevention, a modified healthy lifestyle score was the sum of 4 components addressing use of smoking tobacco, physical activity, diet, and control of systolic blood pressure. Outcome: Cardiovascular and all-cause mortality. Analytical Approach: Adjusted proportional hazards regression analyses with country as a random effect to estimate the associations between lifestyle score (low [0-2 points] as the referent, medium [3-5], and high [6-8]) and mortality. Associations were expressed as adjusted hazard ratio (AHR) with 95% CI. Results: During a median of 3.8 years (17,451 person-years in total), there were 2,163 deaths, of which 826 were related to cardiovascular disease. Compared with patients who had a low lifestyle score, the AHRs for all-cause mortality among those with medium and high lifestyle scores were 0.75 (95% CI, 0.65-0.85) and 0.64 (95% CI, 0.54-0.76), respectively. Compared with patients who had a low lifestyle score, the AHRs for cardiovascular mortality among those with medium and high lifestyle scores were 0.73 (95% CI, 0.59-0.91) and 0.65 (95% CI, 0.49-0.85), respectively. Limitations: Self-reported lifestyle, data-driven approach. Conclusions: A healthier lifestyle is associated with lower all-cause and cardiovascular mortality among patients receiving maintenance hemodialysis.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
Nyckelord
- Blood pressure
- body mass index (BMI)
- cardiovascular disease (CVD)
- chronic kidney disease (CKD)
- cohort
- diet
- DIET-HD
- end-stage renal disease (ESRD)
- hemodialysis
- lifestyle
- modifiable risk factor
- mortality
- physical activity
- smoking
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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