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Fetal sex-specific ...
Fetal sex-specific differences in gestational age at delivery in pre-eclampsia : A meta-analysis
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- Schalekamp-Timmermans, Sarah (författare)
- Erasmus University Medical Center
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- Arends, Lidia R. (författare)
- Erasmus University Rotterdam
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- Alsaker, Elin (författare)
- Norwegian Institute of Public Health
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- Chappell, Lucy (författare)
- King's Health Partners
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- Hansson, Stefan (författare)
- Lund University,Lunds universitet,Obstetrik och gynekologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Enheten för translationell obstetrisk forskning,Forskargrupper vid Lunds universitet,Obstetrics and Gynaecology (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Unit for translational obstetric research,Lund University Research Groups,Skåne University Hospital
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- Harsem, Nina K. (författare)
- Oslo university hospital
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- Jälmby, Maya (författare)
- Lund University,Lunds universitet,Obstetrik och gynekologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Enheten för translationell obstetrisk forskning,Forskargrupper vid Lunds universitet,Obstetrics and Gynaecology (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Unit for translational obstetric research,Lund University Research Groups,Skåne University Hospital
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- Jeyabalan, Arundhathi (författare)
- University of Pittsburgh
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- Laivuori, Hannele (författare)
- University of Helsinki
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- Lawlor, Debbie A. (författare)
- University of Bristol
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- Macdonald-Wallis, Corrie (författare)
- University of Bristol
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- Magnus, Per (författare)
- Norwegian Institute of Public Health
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- Myers, Jenny (författare)
- University of Manchester
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- Olsen, Jørn (författare)
- Aarhus University
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- Poston, Lucilla (författare)
- King's Health Partners
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- Redman, Christopher W. (författare)
- Oxford University Hospital
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- Staff, Anne C. (författare)
- Oslo university hospital
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- Villa, Pia (författare)
- University of Helsinki
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- Roberts, James M. (författare)
- University of Pittsburgh
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- Steegers, Eric A. (författare)
- Erasmus University Medical Center
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(creator_code:org_t)
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- 2016-09-07
- 2017
- Engelska 11 s.
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Ingår i: International Journal of Epidemiology. - : Oxford University Press (OUP). - 0300-5771 .- 1464-3685. ; 46:2, s. 632-642
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http://dx.doi.org/10... (free)
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https://academic.oup...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Background: Pre-eclampsia (PE) is a major pregnancy disorder complicating up to 8% of pregnancies. Increasing evidence indicates a sex-specific interplay between the mother, placenta and fetus. This may lead to different adaptive mechanisms during pregnancy. Methods: We performed an individual participant data meta-analysis to determine associations of fetal sex and PE, with specific focus on gestational age at delivery in PE. This was done on 219 575 independent live-born singleton pregnancies, with a gestational age at birth between 22.0 and 43.0 weeks of gestation, from 11 studies participating in a worldwide consortium of international research groups focusing on pregnancy. Results: Of the women, 9033 (4.1%) experienced PE in their pregnancy and 48.8% of the fetuses were feMale versus 51.2% Male. No differences in the feMale/Male distribution were observed with respect to term PE (delivered > 37 weeks). Preterm PE (delivered < 37 weeks) was slightly more prevalent among pregnancies with a feMale fetus than in pregnancies with a Male fetus [odds ratio (OR) 1.11, 95% confidence interval (CI) 1.02-1.21]. Very preterm PE (delivered < 34 weeks) was even more prevalent among pregnancies with a feMale fetus as compared with pregnancies with a Male fetus (OR 1.36, 95% CI 1.17-1.59). Conclusions: Sexual dimorphic differences in the occurrence of PE exist, with preterm PE being more prevalent among pregnancies with a feMale fetus as compared with pregnancies with a Male fetus and with no differences with respect to term PE.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reproduktionsmedicin och gynekologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Obstetrics, Gynaecology and Reproductive Medicine (hsv//eng)
Nyckelord
- ALSPAC
- Placenta
- Pre-eclampsia
- Sex ratio
- Sexual dimorphism
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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Schalekamp-Timme ...
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Arends, Lidia R.
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Alsaker, Elin
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Chappell, Lucy
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Hansson, Stefan
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Harsem, Nina K.
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Jälmby, Maya
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Jeyabalan, Arund ...
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Laivuori, Hannel ...
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Lawlor, Debbie A ...
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Macdonald-Wallis ...
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Magnus, Per
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Myers, Jenny
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Olsen, Jørn
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Poston, Lucilla
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Redman, Christop ...
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Staff, Anne C.
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Villa, Pia
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Roberts, James M ...
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Steegers, Eric A ...
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