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Transient synovitis...
Transient synovitis of the hip in the child : Increased levels of proteoglycan fragments in joint fluid
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- Lohmander, Stefan (författare)
- Lund University,Lunds universitet,Ortopedi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Orthopaedics (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Wingstrand, H. (författare)
- Skåne University Hospital
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- Heinegard, D. (författare)
- Skåne University Hospital
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(creator_code:org_t)
- 1988
- 1988
- Engelska 5 s.
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Ingår i: Journal of Orthopaedic Research. - 0736-0266. ; 6:3, s. 420-424
- Relaterad länk:
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https://lup.lub.lu.s...
Abstract
Ämnesord
Stäng
- The levels of proteoglycan antigen were measured in joint aspirates from the hip of children with transient synovitis, septic arthritis, Legg-Calve-Perthes' disease and congenital and traumatic dislocation. Significantly increased levels were found in children with transient synovitis and septic arthritis as compared with other conditions. We propose that the proteoglycan antigens in the joint fluid were released form the articular cartilage in a partially degraded from as a result of an increased rate of proteolytic degradation. In transient synovitis, the source of proteolytic activity may be chondrocytes activated by factors released by synovial cells. The release of joint proteoglycan may cause a temporary increase in deformability of the hip cartilage of the child that could be an important pathogenetic mechanism in some of the sequelae of these diseases.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Ortopedi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Orthopaedics (hsv//eng)
Nyckelord
- child
- hip
- Transient synovitis
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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