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Sökning: onr:"swepub:oai:lup.lub.lu.se:e07f359f-d7d3-4724-8ab8-b99e8e2b4feb" > The Analgesic Effec...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00006999naa a2200721 4500
001oai:lup.lub.lu.se:e07f359f-d7d3-4724-8ab8-b99e8e2b4feb
003SwePub
008180907s2018 | |||||||||||000 ||eng|
009oai:DiVA.org:uu-362493
009oai:prod.swepub.kib.ki.se:139017104
009oai:prod.swepub.kib.ki.se:140425983
0247 a https://lup.lub.lu.se/record/e07f359f-d7d3-4724-8ab8-b99e8e2b4feb2 URI
0247 a https://doi.org/10.1016/j.jcin.2018.04.0432 DOI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3624932 URI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1390171042 URI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1404259832 URI
040 a (SwePub)lud (SwePub)uud (SwePub)kid (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
1001 a Sparv, Davidu Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund Univ, Clin Sci, Dept Cardiol, Lund, Sweden4 aut0 (Swepub:lu)med-dzt
2451 0a The Analgesic Effect of Oxygen in Suspected Acute Myocardial Infarction : A Substudy of the DETO2X-AMI Trial
264 1b Elsevier BV,c 2018
300 a 8 s.
520 a Objectives: In this substudy of the DETO2X-AMI (An Efficacy and Outcome Study of Supplemental Oxygen Treatment in Patients With Suspected Myocardial Infarction) trial, the authors aimed to assess the analgesic effect of moderate-flow oxygen supplementation in patients with suspected acute myocardial infarction (AMI) treated with percutaneous coronary intervention (PCI) and to study the effect of oxygen supplementation on the use of opiates and sedatives during PCI. Background: Routine oxygen in normoxemic patients with AMI does not provide clinical benefit. However, oxygen may relieve ischemic pain. Methods: Patients were randomly allocated to oxygen or ambient air according to the main study protocol. After PCI, peak level of pain during PCI was measured by the Visual Analogue Scale. The total amount of opiates and sedatives was reported. Results: A total of 622 patients were enrolled: 330 in the oxygen group and 292 in the ambient air group. There was no significant difference in peak level of pain (oxygen 4.0 [1.0 to 6.0] vs. air 3.0 [0.6 to 6.0]; p = 0.37), use of opiates (mg) (oxygen 0.0 [0.0 to 3.0] vs. air 0.0 [0.0 to 3.0]; p = 0.31), or use of sedatives between the groups (median [interquartile range]) (oxygen 2.5 [0.0 to 2.5] vs. air 2.5 [0.0 to 2.5]; p = 0.74). Conclusions: In the present study, the authors did not find any analgesic effect of routine oxygen as compared with ambient air, and no differences in the use of sedatives and opiates during PCI. Our results indicate that moderate-flow oxygen supplementation does not relieve pain in normoxemic patients with suspected AMI undergoing treatment with PCI and should thus not be used for this purpose.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
653 a analgesic effect
653 a oxygen
653 a ST-segment elevation myocardial infarction
653 a analgesic effect
7001 a Hofmann, Robinu Karolinska Institutet,Karolinska Institute,Stockholm South General Hospital,Karolinska Inst, Sodersjukhuset, Div Cardiol, Dept Clin Sci & Educ, Stockholm, Sweden4 aut
7001 a Gunnarsson, Annikau Uppsala University Hospital,Uppsala Univ Hosp, Dept Cardiol, Uppsala, Sweden4 aut
7001 a James, Stefan K,d 1964-u Uppsala universitet,Uppsala University,Kardiologi,Uppsala kliniska forskningscentrum (UCR)4 aut0 (Swepub:uu)stjam367
7001 a Hedberg, Camillau Ryhov County Hospital, Jönköping,Ryhov Hosp, Dept Internal Med, Div Cardiol, Jonkoping, Sweden4 aut
7001 a Lauermann, Jörgu Ryhov County Hospital, Jönköping,Ryhov Hosp, Dept Internal Med, Div Cardiol, Jonkoping, Sweden4 aut
7001 a Torild, Petronellau Sahlgrenska University Hospital,Sahlgrens Univ Hosp, Dept Cardiol, Gothenburg, Sweden4 aut
7001 a Omerovic, Elmiru Sahlgrenska University Hospital,Sahlgrens Univ Hosp, Dept Cardiol, Gothenburg, Sweden4 aut
7001 a Bergström, Kristinau Gävle Hospital,Gavle Sjukhus, Dept Cardiol, Gavle, Sweden4 aut
7001 a Haugen, Espenu Sundsvall Hospital,Sundsvall Reg Hosp, Dept Cardiol, Sundsvall, Sweden4 aut
7001 a Bergström, Camillau Danderyd Hospital,Danderyd Hosp, Dept Cardiol, Stockholm, Sweden4 aut
7001 a Linder, Rikardu Karolinska Institutet4 aut
7001 a Borg, Piau Svensk PCI Varmland AB, Karlstad, Sweden4 aut
7001 a Haaga, Urbanu Karlstad Hospital,Cent Hosp Karlstad, Dept Cardiol, Karlstad, Sweden4 aut
7001 a Olsson, Anneliu Skåne University Hospital,Skane Univ Hosp, Dept Cardiol, Lund, Sweden4 aut0 (Swepub:lu)an8011ol
7001 a Böving, Elinu Stockholm South General Hospital,Soder Sjukhuset, Dept Cardiol, Stockholm, Sweden4 aut
7001 a Östlund, Ollieu Uppsala universitet,Uppsala University,Uppsala kliniska forskningscentrum (UCR)4 aut0 (Swepub:uu)oos27600
7001 a Rylance, Rebeccau Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Lund Univ, Clin Sci, Dept Cardiol, Lund, Sweden4 aut0 (Swepub:lu)re4842ry
7001 a Witt, Nilsu Karolinska Institutet,Karolinska Institute,Stockholm South General Hospital,Karolinska Inst, Sodersjukhuset, Div Cardiol, Dept Clin Sci & Educ, Stockholm, Sweden4 aut
7001 a Erlinge, Davidu Lund University,Lunds universitet,Molekylär kardiologi,Forskargrupper vid Lunds universitet,Molecular Cardiology,Lund University Research Groups,Lund Univ, Clin Sci, Dept Cardiol, Lund, Sweden4 aut0 (Swepub:lu)kard-der
7001 a James, SJ4 aut
7102 a Kardiologib Sektion II4 org
7102 a DETO2X-SWEDEHEART Investigators
7730 t JACC: Cardiovascular Interventionsd : Elsevier BVg 39, s. 546-546q 11:16<1590-1597x 1936-8798x 1876-7605
7730 t EUROPEAN HEART JOURNALd : Elsevier BVg 39, s. 546-546q 39<546-546x 0195-668X
8564 u http://dx.doi.org/10.1016/j.jcin.2018.04.043y FULLTEXT
8564 u https://doi.org/10.1016/j.jcin.2018.04.043
8564 8u https://lup.lub.lu.se/record/e07f359f-d7d3-4724-8ab8-b99e8e2b4feb
8564 8u https://doi.org/10.1016/j.jcin.2018.04.043
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-362493
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:139017104
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:140425983

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