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Pleuropulmonary pat...
Pleuropulmonary pathologies in the early phase of acute pancreatitis correlate with disease severity
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- Luiken, Ina (författare)
- Universitätsklinikum Halle,Martin-Luther-Universität Halle-Wittenberg
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- Eisenmann, Stephan (författare)
- Martin-Luther-Universität Halle-Wittenberg,Universitätsklinikum Halle
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- Garbe, Jakob (författare)
- Universitätsklinikum Halle,Martin-Luther-Universität Halle-Wittenberg
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- Sternby, Hanna (författare)
- Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups
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- Verdonk, Robert C. (författare)
- St. Antonius Hospital
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- Dimova, Alexandra (författare)
- Pirogov Hospital
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- Ignatavicius, Povilas (författare)
- Lithuanian University of Health Sciences
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- Ilzarbe, Lucas (författare)
- Hospital del Mar Medical Research Institute
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- Koiva, Peeter (författare)
- East Tallinn Central Hospital
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- Penttilä, Anne K. (författare)
- Helsinki University Central Hospital,University of Helsinki
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- Regnér, Sara (författare)
- Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups
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- Dober, Johannes (författare)
- Universitätsklinikum Halle,Martin-Luther-Universität Halle-Wittenberg
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- Wohlgemuth, Walter A. (författare)
- Universitätsklinikum Halle,Martin-Luther-Universität Halle-Wittenberg
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- Brill, Richard (författare)
- Martin-Luther-Universität Halle-Wittenberg,Universitätsklinikum Halle
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- Michl, Patrick (författare)
- Universitätsklinikum Halle,Martin-Luther-Universität Halle-Wittenberg
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- Rosendahl, Jonas (författare)
- Martin-Luther-Universität Halle-Wittenberg,Universitätsklinikum Halle
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- Damm, Marko (författare)
- Martin-Luther-Universität Halle-Wittenberg,Universitätsklinikum Halle
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(creator_code:org_t)
- 2022-02-07
- 2022
- Engelska.
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Ingår i: PLoS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 17:2 February
- Relaterad länk:
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http://dx.doi.org/10... (free)
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https://journals.plo...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Background Respiratory failure worsens the outcome of acute pancreatitis (AP) and underlying factors might be early detectable. Aims To evaluate the prevalence and prognostic relevance of early pleuropulmonary pathologies and pre-existing chronic lung diseases (CLD) in AP patients. Methods Multicentre retrospective cohort study. Caudal sections of the thorax derived from abdominal contrast enhanced computed tomography (CECT) performed in the early phase of AP were assessed. Independent predictors of severe AP were identified by binary logistic regression analysis. A one-year survival analysis using Kaplan-Meier curves and log rank test was performed. Results 358 patients were analysed, finding pleuropulmonary pathologies in 81%. CECTs were performed with a median of 2 days (IQR 1–3) after admission. Multivariable analysis identified moderate to severe or bilateral pleural effusions (PEs) (OR = 4.16, 95%CI 2.05–8.45, p<0.001) and pre-existing CLD (OR = 2.93, 95%CI 1.17–7.32, p = 0.022) as independent predictors of severe AP. Log rank test showed a significantly worse one-year survival in patients with bilateral compared to unilateral PEs in a subgroup. Conclusions Increasing awareness of the prognostic impact of large and bilateral PEs and pre-existing CLD could facilitate the identification of patients at high risk for severe AP in the early phase and thus improve their prognosis.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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PLoS ONE
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- Av författaren/redakt...
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Luiken, Ina
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Eisenmann, Steph ...
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Garbe, Jakob
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Sternby, Hanna
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Verdonk, Robert ...
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Dimova, Alexandr ...
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visa fler...
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Ignatavicius, Po ...
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Ilzarbe, Lucas
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Koiva, Peeter
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Penttilä, Anne K ...
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Regnér, Sara
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Dober, Johannes
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Wohlgemuth, Walt ...
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Brill, Richard
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Michl, Patrick
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Rosendahl, Jonas
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Damm, Marko
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kirurgi
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PLoS ONE
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Lunds universitet