onr:"swepub:oai:lup.lub.lu.se:e8bdb13c-f36d-448a-8c4e-89bc36c3b833"
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 05082naa a2200469 4500 | |
| 001 | oai:lup.lub.lu.se:e8bdb13c-f36d-448a-8c4e-89bc36c3b833 | |
| 003 | SwePub | |
| 008 | 160401s2014 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://lup.lub.lu.se/record/44386632 URI |
| 024 | 7 | a https://doi.org/10.1186/1741-7015-12-622 DOI |
| 040 | a (SwePub)lu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a art2 swepub-publicationtype |
| 072 | 7 | a ref2 swepub-contenttype |
| 100 | 1 | a Timpka, Simonu Lund University,Lunds universitet,Ortopedi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Orthopaedics (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Genetic and Molecular Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)med-stp |
| 245 | 1 0 | a Muscle strength in adolescent men and risk of cardiovascular disease events and mortality in middle age: a prospective cohort study |
| 264 | c 2014-04-14 | |
| 264 | 1 | b Springer Science and Business Media LLC,c 2014 |
| 338 | a electronic2 rdacarrier | |
| 520 | a Background Ischemic heart disease and stroke are two severe types of cardiovascular disease (CVD), a major contributor to the global burden of disease. The preventive framework currently includes promotion of both adequate cardiorespiratory and muscular fitness. Although muscle fitness is established as an indicator of health, it is currently unknown whether muscle strength is associated with later CVD independently of cardiorespiratory fitness. Methods We studied 38,588 Swedish men who in 1969 to 1970 (typically aged 18 years) completed compulsory conscription. Using the mean standardized score of three isometric muscle strength tests performed at conscription (hand grip, elbow flexion and knee extension), we categorized the subjects into three groups with the 25th to 75th percentile defining the reference category. We followed the cohort until 2012 for diagnosed CVD events and mortality via national health care registers and the national cause of death register. To estimate hazard ratios (HR) for CVD events (coronary heart disease or stroke) and CVD mortality we used Cox proportional hazard models adjusted for body mass index, smoking, alcohol consumption, cardiorespiratory fitness and socioeconomic status. Results Men with high muscle strength in adolescence had a decreased risk of later CVD events (HR 0.88, 95% confidence interval 0.77 to 0.99), whereas we observed no increased risk in men with low muscle strength (0.99, 0.86 to 1.13). However, low muscle strength was associated with increased risk of CVD mortality during middle age (1.31, 1.02 to 1.67). Conclusions Muscle strength in adolescent men is inversely associated with later CVD events and CVD mortality in middle age, independently of cardiorespiratory fitness and other important confounders. Thus, the role of muscle fitness in the prevention and pathogenesis of CVD warrants increased attention. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Endokrinologi och diabetes0 (SwePub)302052 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Endocrinology and Diabetes0 (SwePub)302052 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Ortopedi0 (SwePub)302112 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Orthopaedics0 (SwePub)302112 hsv//eng |
| 653 | a Cardiovascular disease | |
| 653 | a Coronary heart disease | |
| 653 | a Stroke | |
| 653 | a Muscle strength | |
| 653 | a Prevention | |
| 653 | a Epidemiology | |
| 700 | 1 | a Petersson, Ingemaru Lund University,Lunds universitet,Ortopedi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Orthopaedics (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)ort-ipe |
| 700 | 1 | a Zhou, Caddieu Lund University,Lunds universitet,Ortopedi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Orthopaedics (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)ort-czh |
| 700 | 1 | a Englund, Martinu Lund University,Lunds universitet,Ortopedi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Orthopaedics (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine4 aut0 (Swepub:lu)ort-med |
| 710 | 2 | a Ortopedi, Lundb Sektion III4 org |
| 773 | 0 | t BMC Medicined : Springer Science and Business Media LLCg 12:1q 12:1x 1741-7015 |
| 856 | 4 | u https://portal.research.lu.se/files/3896058/4438665x primaryx freey FULLTEXT |
| 856 | 4 | u http://www.ncbi.nlm.nih.gov/pubmed/?term=24731728x freey FULLTEXT |
| 856 | 4 | u http://dx.doi.org/10.1186/1741-7015-12-62x freey FULLTEXT |
| 856 | 4 | u https://bmcmedicine.biomedcentral.com/track/pdf/10.1186/1741-7015-12-62 |
| 856 | 4 8 | u https://lup.lub.lu.se/record/4438663 |
| 856 | 4 8 | u https://doi.org/10.1186/1741-7015-12-62 |
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