Sökning: onr:"swepub:oai:lup.lub.lu.se:ed1f5b88-f7bc-4a36-9a45-b3899d791779" >
Automated interpret...
-
Gutte, Henrik
(författare)
Automated interpretation of PET/CT images in patients with lung cancer.
- Artikel/kapitelEngelska2007
Förlag, utgivningsår, omfång ...
Nummerbeteckningar
-
LIBRIS-ID:oai:lup.lub.lu.se:ed1f5b88-f7bc-4a36-9a45-b3899d791779
-
https://lup.lub.lu.se/record/165186URI
-
https://doi.org/10.1097/MNM.0b013e328013eaceDOI
Kompletterande språkuppgifter
-
Språk:engelska
-
Sammanfattning på:engelska
Ingår i deldatabas
Klassifikation
-
Ämneskategori:art swepub-publicationtype
-
Ämneskategori:ref swepub-contenttype
Anmärkningar
-
Purpose: To develop a completely automated method based on image processing techniques and artificial neural networks for the interpretation of combined [18F]fluorodeoxyglucose (FDG) positron emission tomography (PET) and computed tomography (CT) images for the diagnosis and staging of lung cancer. Methods: A total of 87 patients who underwent PET/CT examinations due to suspected lung cancer comprised the training group. The test group consisted of PET/CT images from 49 patients suspected with lung cancer. The consensus interpretations by two experienced physicians were used as the 'gold standard' image interpretation. The training group was used in the development of the automated method. The image processing techniques included algorithms for segmentation of the lungs based on the CT images and detection of lesions in the PET images. Lung boundaries from the CT images were used for localization of lesions in the PET images in the feature extraction process. Eight features from each examination were used as inputs to artificial neural networks trained to classify the images. Thereafter, the performance of the network was evaluated in the test set. Results: The performance of the automated method measured as the area under the receiver operating characteristic curve, was 0.97 in the test group, with an accuracy of 92%. The sensitivity was 86% at a specificity of 100%. Conclusions: A completely automated method using artificial neural networks can be used to detect lung cancer with such a high accuracy that the application as a clinical decision support tool appears to have significant potential.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
-
Jakobsson, David
(författare)
-
Olofsson, Fredrik
(författare)
-
Ohlsson, MattiasLund University,Lunds universitet,Beräkningsbiologi och biologisk fysik - Genomgår omorganisation,Institutionen för astronomi och teoretisk fysik - Genomgår omorganisation,Naturvetenskapliga fakulteten,Computational Biology and Biological Physics - Undergoing reorganization,Department of Astronomy and Theoretical Physics - Undergoing reorganization,Faculty of Science(Swepub:lu)thep-moh
(författare)
-
Valind, SvenLund University,Lunds universitet,Klinisk fysiologi och nuklearmedicin, Malmö,Forskargrupper vid Lunds universitet,Clinical Physiology and Nuclear Medicine, Malmö,Lund University Research Groups(Swepub:lu)klin-sva
(författare)
-
Loft, Annika
(författare)
-
Edenbrandt, LarsLund University,Lunds universitet,Institutionen för translationell medicin,Medicinska fakulteten,Department of Translational Medicine,Faculty of Medicine(Swepub:lu)klfy-led
(författare)
-
Kjær, Andreas
(författare)
-
Beräkningsbiologi och biologisk fysik - Genomgår omorganisationInstitutionen för astronomi och teoretisk fysik - Genomgår omorganisation
(creator_code:org_t)
Sammanhörande titlar
-
Ingår i:Nuclear Medicine Communications28:2, s. 79-841473-5628
Internetlänk
Hitta via bibliotek
Till lärosätets databas