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Genetic mechanisms ...
Genetic mechanisms underlying arrhythmogenic mitral valve prolapse : Current and future perspectives
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Levy, Sydney (författare)
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- Sharaf Dabbagh, Ghaith (författare)
- University of Michigan
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- Giudicessi, John R. (författare)
- Mayo Clinic Minnesota
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- Haqqani, Haris (författare)
- The Prince Charles Hospital
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- Khanji, Mohammed Y. (författare)
- Queen Mary University,Newham University Hospital
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Obeng-Gyimah, Edmond (författare)
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Betts, Megan N. (författare)
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- Ricci, Fabrizio (författare)
- Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups,University G.d'Annunzio of Chieti-Pescara
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- Asatryan, Babken (författare)
- Johns Hopkins University School of Medicine
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Bouatia-Naji, Nabila (författare)
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- Nazarian, Saman (författare)
- University of Pennsylvania
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- Chahal, C. Anwar A. (författare)
- Mayo Clinic Minnesota,Hospital of the University of Pennsylvania,Barts Health NHS Trust
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(creator_code:org_t)
- 2023
- 2023
- Engelska 11 s.
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Ingår i: Heart Rhythm O2. - 2666-5018. ; 4:9, s. 581-591
- Relaterad länk:
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http://dx.doi.org/10... (free)
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Mitral valve prolapse (MVP) is a heart valve disease that is often familial, affecting 2%–3% of the general population. MVP with or without mitral regurgitation can be associated with an increased risk of ventricular arrhythmias and sudden cardiac death (SCD). Research on familial MVP has specifically focused on genetic factors, which may explain the heritable component of the disease estimated to be present in 20%–35%. Furthermore, the structural and electrophysiological substrates underlying SCD/ventricular arrhythmia risk in MVP have been studied postmortem and in the electrophysiology laboratory, respectively. Understanding how familial MVP and rhythm disorders are related may help patients with MVP by individualizing risk and working to develop effective management strategies. This contemporary, state-of-the-art, expert review focuses on genetic factors and familial components that underlie MVP and arrhythmia and encapsulates clinical, genetic, and electrophysiological issues that should be the objectives of future research.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- Cardiac arrhythmia
- Genetics
- Mitral annular dysjunction
- Mitral valve prolapse
- Sudden cardiac death
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- Av författaren/redakt...
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Levy, Sydney
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Sharaf Dabbagh, ...
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Giudicessi, John ...
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Haqqani, Haris
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Khanji, Mohammed ...
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Obeng-Gyimah, Ed ...
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Betts, Megan N.
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Ricci, Fabrizio
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Asatryan, Babken
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Bouatia-Naji, Na ...
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Nazarian, Saman
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Chahal, C. Anwar ...
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kardiologi
- Artiklar i publikationen
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Heart Rhythm O2
- Av lärosätet
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Lunds universitet