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Sökning: onr:"swepub:oai:lup.lub.lu.se:f0f696ce-f40b-4edc-a374-a09a1071e244" > Coronary Plaque in ...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00005552naa a2200685 4500
001oai:lup.lub.lu.se:f0f696ce-f40b-4edc-a374-a09a1071e244
003SwePub
008240516s2024 | |||||||||||000 ||eng|
0247 a https://lup.lub.lu.se/record/f0f696ce-f40b-4edc-a374-a09a1071e2442 URI
0247 a https://doi.org/10.1016/j.jacadv.2024.1009682 DOI
040 a (SwePub)lu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
1001 a Karady, Juliau Semmelweis University,Massachusetts General Hospital4 aut
2451 0a Coronary Plaque in People With HIV vs Non-HIV Asymptomatic Community and Symptomatic Higher-Risk Populations
264 1c 2024
520 a Background: People with HIV (PWH) have a high burden of coronary plaques; however, the comparison to people without known HIV (PwoH) needs clarification. Objectives: The purpose of this study was to determine coronary plaque burden/phenotype in PWH vs PwoH. Methods: Nonstatin using participants from 3 contemporary populations without known coronary plaques with coronary CT were compared: the REPRIEVE (Randomized Trial to Prevent Vascular Events in HIV) studying PWH without cardiovascular symptoms at low-to-moderate risk (n = 755); the SCAPIS (Swedish Cardiopulmonary Bioimage Study) of asymptomatic community PwoH at low-to-intermediate cardiovascular risk (n = 23,558); and the PROMISE (Prospective Multicenter Imaging Study for Evaluation of Chest Pain) of stable chest pain PwoH (n = 2,291). The coronary plaque prevalence on coronary CT was compared, and comparisons were stratified by 10-year atherosclerotic cardiovascular disease (ASCVD) risk, age, and coronary artery calcium (CAC) presence. Results: Compared to SCAPIS and PROMISE PwoH, REPRIEVE PWH were younger (50.8 ± 5.8 vs 57.3 ± 4.3 and 60.0 ± 8.0 years; P < 0.001) and had lower ASCVD risk (5.0% ± 3.2% vs 6.0% ± 5.3% and 13.5% ± 11.0%; P < 0.001). More PWH had plaque compared to the asymptomatic cohort (48.5% vs 40.3%; P < 0.001). When stratified by ASCVD risk, PWH had more plaque compared to SCAPIS and a similar prevalence of plaque compared to PROMISE. CAC = 0 was more prevalent in PWH (REPRIEVE 65.2%; SCAPIS 61.6%; PROMISE 49.6%); among CAC = 0, plaque was more prevalent in PWH compared to the PwoH cohorts (REPRIEVE 20.8%; SCAPIS 5.4%; PROMISE 12.3%, P < 0.001). Conclusions: Asymptomatic PWH in REPRIEVE had more plaque than asymptomatic PwoH in SCAPIS but had similar prevalence to a higher-risk stable chest pain cohort in PROMISE. In PWH, CAC = 0 does not reliably exclude plaque.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
653 a asymptomatic community cohort
653 a cardiovascular disease
653 a coronary CT angiography
653 a coronary plaque
653 a people with HIV
653 a stable chest pain
7001 a Lu, Michael T.u Massachusetts General Hospital4 aut
7001 a Bergström, Göranu Sahlgrenska Academy,Sahlgrenska University Hospital4 aut
7001 a Mayrhofer, Thomasu Massachusetts General Hospital,University of Applied Sciences Stralsund4 aut
7001 a Taron, Janau University Medical Center Freiburg,Massachusetts General Hospital4 aut
7001 a Foldyna, Boreku Massachusetts General Hospital4 aut
7001 a Paradis, Kaylau Massachusetts General Hospital4 aut
7001 a McCallum, Sarau Massachusetts General Hospital4 aut
7001 a Aberg, Judith A.u Icahn School of Medicine at Mount Sinai4 aut
7001 a Currier, Judith S.u University of California, Los Angeles4 aut
7001 a Fitch, Kathleen V.u Massachusetts General Hospital4 aut
7001 a Fulda, Evelynne S.u Massachusetts General Hospital4 aut
7001 a Bloomfield, Gerald S.u Duke Clinical Research Institute (DCRI)4 aut
7001 a Overton, Edgar T.4 aut
7001 a Lind, Larsu Uppsala University4 aut
7001 a Östgren, Carl Johanu Linköping University4 aut
7001 a Elvstam, Olofu Lund University,Lunds universitet,Klinisk infektionsmedicin,Forskargrupper vid Lunds universitet,Clinical infection medicine,Lund University Research Groups,Växjö Central Hospital4 aut0 (Swepub:lu)ol8873el
7001 a Söderberg, Stefanu Umeå University4 aut
7001 a Jernberg, Tomasu Danderyd Hospital4 aut
7001 a Pepe, Rosalieu Cooper University Hospital, Camden4 aut
7001 a Dubé, Michael P.u University of Southern California4 aut
7001 a Mushatt, Davidu Tulane University School of Medicine4 aut
7001 a Fichtenbaum, Carl J.u University of Cincinnati4 aut
7001 a Malvestutto, Carlosu Ohio State University4 aut
7001 a Zanni, Markella V.u Massachusetts General Hospital4 aut
7001 a Hoffmann, Udou Massachusetts General Hospital4 aut
7001 a Ribaudo, Heather4 aut
7001 a Grinspoon, Steven K.u Massachusetts General Hospital4 aut
7001 a Douglas, Pamela S.u Duke Clinical Research Institute (DCRI)4 aut
7102 a Semmelweis Universityb Massachusetts General Hospital4 org
7730 t JACC: Advancesg 3:6q 3:6x 2772-963X
8564 u http://dx.doi.org/10.1016/j.jacadv.2024.100968x freey FULLTEXT
8564 8u https://lup.lub.lu.se/record/f0f696ce-f40b-4edc-a374-a09a1071e244
8564 8u https://doi.org/10.1016/j.jacadv.2024.100968

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