Sökning: onr:"swepub:oai:lup.lub.lu.se:f8635823-82a0-4f37-bf10-dcc2e28f635b" >
Defining HIV-1 tran...
-
Hassan, Amin S.Lund University,Lunds universitet,Klinisk virologi, Malmö,Forskargrupper vid Lunds universitet,Clinical Virology, Malmö,Lund University Research Groups,Centre for Geographic Medicine Research, Kilifi
(författare)
Defining HIV-1 transmission clusters based on sequence data : a systematic review and perspectives
- Artikel/kapitelEngelska2017
Förlag, utgivningsår, omfång ...
Nummerbeteckningar
-
LIBRIS-ID:oai:lup.lub.lu.se:f8635823-82a0-4f37-bf10-dcc2e28f635b
-
https://lup.lub.lu.se/record/f8635823-82a0-4f37-bf10-dcc2e28f635bURI
-
https://doi.org/10.1097/QAD.0000000000001470DOI
Kompletterande språkuppgifter
-
Språk:engelska
-
Sammanfattning på:engelska
Ingår i deldatabas
Klassifikation
-
Ämneskategori:for swepub-publicationtype
-
Ämneskategori:ref swepub-contenttype
Anmärkningar
-
Understanding HIV-1 transmission dynamics is relevant to both screening and intervention strategies of HIV-1 infection. Commonly, HIV-1 transmission chains are determined based on sequence similarity assessed either directly from a sequence alignment or by inferring a phylogenetic tree. This review is aimed at both nonexperts interested in understanding and interpreting studies of HIV-1 transmission, and experts interested in finding the most appropriate cluster definition for a specific dataset and research question. We start by introducing the concepts and methodologies of how HIV-1 transmission clusters usually have been defined. We then present the results of a systematic review of 105 HIV-1 molecular epidemiology studies summarising the most popular methods and definitions in the literature. Finally, we offer our perspectives on how HIV-1 transmission clusters can be defined and provide some guidance based on examples from real life datasets.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
-
Pybus, Oliver GUniversity of Oxford
(författare)
-
Sanders, Eduard J.Centre for Geographic Medicine Research, Kilifi,University of Oxford
(författare)
-
Albert, JanKarolinska Institute
(författare)
-
Esbjörnsson, JoakimKarolinska Institute,University of Oxford(Swepub:lu)med-jes
(författare)
-
Klinisk virologi, MalmöForskargrupper vid Lunds universitet
(creator_code:org_t)
Sammanhörande titlar
-
Ingår i:AIDS31:9, s. 1211-12220269-9370
Internetlänk
Hitta via bibliotek
-
AIDS
(Sök värdpublikationen i LIBRIS)
Till lärosätets databas