Sökning: onr:"swepub:oai:openarchive.ki.se:10616/46106" > From transcriptiona...
Fältnamn | Indikatorer | Metadata |
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000 | 02718naa a2200421 4500 | |
001 | oai:openarchive.ki.se:10616/46106 | |
003 | SwePub | |
008 | 240910s2017 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:137196542 | |
022 | a 0749-503X | |
024 | 7 | a 10616/461062 hdl |
024 | 7 | a http://hdl.handle.net/10616/461062 URI |
024 | 7 | a https://doi.org/10.1002/yea.32772 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1371965422 URI |
040 | a (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Pelechano, Vicentu Karolinska Institutet4 aut |
245 | 1 0 | a From transcriptional complexity to cellular phenotypes : lessons from yeast |
264 | c 2017-10-11 | |
264 | 1 | a Stockholm :b Karolinska Institutet, Dept of Microbiology, Tumor and Cell Biology,c 2017 |
338 | a electronic2 rdacarrier | |
520 | a Pervasive transcription has been reported in many eukaryotic organisms, revealing a highly interleaved transcriptome organization that involves thousands of coding and non-coding RNAs. However, to date, the biological impact of transcriptome complexity is still poorly understood. Here I will review how subtle variations of the transcriptome can lead to divergent cellular phenotypes by fine-tuning both its coding potential and regulation. I will discuss strategies that can be used to link molecular variations with divergent biological outcomes. Finally, I will explore the implication of transcriptional complexity for our understanding of gene expression in the context of cell-to-cell phenotypic variability. | |
650 | 7 | a NATURVETENSKAPx Biologix Bioinformatik och systembiologi0 (SwePub)106102 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Bioinformatics and Systems Biology0 (SwePub)106102 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinsk bioteknologix Medicinsk bioteknologi0 (SwePub)304012 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Medical Biotechnologyx Medical Biotechnology0 (SwePub)304012 hsv//eng |
710 | 2 | a Karolinska Institutet |
710 | 2 | a Karolinska Institutet |
710 | 2 | a Karolinska Institutet4 org |
773 | 0 | t Yeastd Stockholm : Karolinska Institutet, Dept of Microbiology, Tumor and Cell Biologyx 0749-503Xx 1097-0061 |
856 | 4 | u http://hdl.handle.net/10616/46106x primaryx Object in contextx freey FULLTEXT |
856 | 4 | u http://openarchive.ki.se/xmlui/bitstream/10616/46106/3/10.1002_yea.3277.pdf |
856 | 4 8 | u http://hdl.handle.net/10616/46106 |
856 | 4 8 | u https://doi.org/10.1002/yea.3277 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:137196542 |
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