SwePub
Sök i LIBRIS databas

  Utökad sökning

onr:"swepub:oai:prod.swepub.kib.ki.se:124436568"
 

Sökning: onr:"swepub:oai:prod.swepub.kib.ki.se:124436568" > Gender influences s...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00002521naa a2200337 4500
001oai:prod.swepub.kib.ki.se:124436568
003SwePub
008240701s2012 | |||||||||||000 ||eng|
024a http://kipublications.ki.se/Default.aspx?queryparsed=id:1244365682 URI
024a https://doi.org/10.1159/0003375702 DOI
040 a (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Savendahl, Lu Karolinska Institutet4 aut
2451 0a Gender influences short-term growth hormone treatment response in children
264 c 2012-04-12
264 1b S. Karger AG,c 2012
520 a <b><i>Background:</i></b> Gender may affect growth hormone (GH) treatment outcome. This study assessed gender-related differences in change from baseline height standard deviation scores (ΔHSDS) after 2 years’ GH treatment. <b><i>Methods:</i></b> Data from two observational databases were analyzed – the NordiNet® International Outcome Study (NordiNet® IOS) and the American Norditropin Studies: Web Enabled Research Program (ANSWER Program®). Of all the evaluated patients (n = 5,880; age 0 to <18 years), 4,471 were diagnosed with GH deficiency (GHD), 422 with multiple pituitary hormone deficiency, and 987 were born small for gestational age (SGA). Data were analyzed by indication, gender and pubertal status (total population/prepubertal). <b><i>Results:</i></b> In the total population, after correcting for dose, mean baseline age and HSDS, ΔHSDS was significantly greater in boys than in girls born SGA (p = 0.0261). In the prepubertal cohort, ΔHSDS was significantly greater for boys versus girls with GHD (p = 0.0004) and SGA (p = 0.0019). No between-gender difference in ΔIGF-I SDS was found. <b><i>Conclusions:</i></b> A significant gender difference was found in the 2-year response to GH treatment in the total population of SGA children as well as in the prepubertal cohorts of SGA and GHD children.
700a Blankenstein, O4 aut
700a Oliver, I4 aut
700a Christesen, HT4 aut
700a Lee, P4 aut
700a Pedersen, BT4 aut
700a Rakov, V4 aut
700a Ross, J4 aut
710a Karolinska Institutet4 org
773t Hormone research in paediatricsd : S. Karger AGg 77:3, s. 188-194q 77:3<188-194x 1663-2826x 1663-2818
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:124436568
8564 8u https://doi.org/10.1159/000337570

Hitta via bibliotek

Till lärosätets databas

Sök utanför SwePub

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy