Sökning: onr:"swepub:oai:prod.swepub.kib.ki.se:133801806" > Genetic and environ...
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024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1338018062 URI |
024 | 7 | a https://doi.org/10.1038/srep284962 DOI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-510762 URI |
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041 | a engb eng | |
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100 | 1 | a Jelenkovic, Au Department of Social Research, University of Helsinki, Helsinki, Finland; Department of Genetics, Physical Anthropology and Animal Physiology, University of the Basque Country UPV/EHU, Leioa, Spain4 aut |
245 | 1 0 | a Genetic and environmental influences on height from infancy to early adulthood: An individual-based pooled analysis of 45 twin cohorts |
264 | c 2016-06-23 | |
264 | 1 | a London, United Kingdom :b Springer Science and Business Media LLC,c 2016 |
520 | a Height variation is known to be determined by both genetic and environmental factors, but a systematic description of how their influences differ by sex, age and global regions is lacking. We conducted an individual-based pooled analysis of 45 twin cohorts from 20 countries, including 180,520 paired measurements at ages 1–19 years. The proportion of height variation explained by shared environmental factors was greatest in early childhood, but these effects remained present until early adulthood. Accordingly, the relative genetic contribution increased with age and was greatest in adolescence (up to 0.83 in boys and 0.76 in girls). Comparing geographic-cultural regions (Europe, North-America and Australia and East-Asia), genetic variance was greatest in North-America and Australia and lowest in East-Asia, but the relative proportion of genetic variation was roughly similar across these regions. Our findings provide further insights into height variation during childhood and adolescence in populations representing different ethnicities and exposed to different environments. | |
650 | 7 | a NATURVETENSKAPx Biologix Evolutionsbiologi0 (SwePub)106152 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Evolutionary Biology0 (SwePub)106152 hsv//eng |
650 | 7 | a NATURVETENSKAPx Biologix Genetik0 (SwePub)106092 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Genetics0 (SwePub)106092 hsv//eng |
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700 | 1 | a Magnusson, PKEu Karolinska Institutet4 aut |
700 | 1 | a Pedersen, NLu Karolinska Institutet4 aut |
700 | 1 | a Ooki, S4 aut |
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700 | 1 | a Stazi, MA4 aut |
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700 | 1 | a Huibregtse, BM4 aut |
700 | 1 | a Derom, CA4 aut |
700 | 1 | a Vlietinck, RFu Karolinska Institutet4 aut |
700 | 1 | a Loos, RJF4 aut |
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700 | 1 | a Wardle, J4 aut |
700 | 1 | a Llewellyn, CH4 aut |
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700 | 1 | a Tuvblad, Catherine,d 1968-u Örebro universitet,Institutionen för juridik, psykologi och socialt arbete4 aut0 (Swepub:oru)ctd |
700 | 1 | a Gregory, AM4 aut |
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700 | 1 | a Boomsma, DI4 aut |
700 | 1 | a Kaprio, J4 aut |
700 | 1 | a Silventoinen, Ku Department of Social Research, University of Helsinki, Helsinki, Finland; Osaka University Graduate School of Medicine, Osaka University, Osaka, Japan4 aut |
710 | 2 | a Karolinska Institutetb Department of Social Research, University of Helsinki, Helsinki, Finland; Department of Genetics, Physical Anthropology and Animal Physiology, University of the Basque Country UPV/EHU, Leioa, Spain4 org |
773 | 0 | t Scientific reportsd London, United Kingdom : Springer Science and Business Media LLCg 6, s. 28496-q 6<28496-x 2045-2322 |
856 | 4 | u https://www.nature.com/articles/srep28496.pdf |
856 | 4 | u https://doi.org/10.1038/srep28496y Fulltext |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:133801806 |
856 | 4 8 | u https://doi.org/10.1038/srep28496 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-51076 |
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