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Determinants of Cro...
Determinants of Cross-Sectional and Longitudinal Health-Related Quality of Life in Memory Clinic Patients Without Dementia
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Banning, LCP (författare)
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Janssen, EPCJ (författare)
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Hamel, REG (författare)
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visa fler...
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de Vugt, M (författare)
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Kohler, S (författare)
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Wolfs, CAG (författare)
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Oosterveld, SM (författare)
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Melis, RJF (författare)
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Rikkert, MGMO (författare)
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Kessels, RPC (författare)
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Pijnenburg, YAL (författare)
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Koene, T (författare)
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van der Flier, WM (författare)
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Scheltens, P (författare)
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- Visser, PJ (författare)
- Karolinska Institutet
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Verhey, FRJ (författare)
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Aalten, P (författare)
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Ramakers, IHGB (författare)
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(creator_code:org_t)
- 2019-10-23
- 2020
- Engelska.
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Ingår i: Journal of geriatric psychiatry and neurology. - : SAGE Publications. - 0891-9887 .- 1552-5708. ; 33:5, s. 256-264
- Relaterad länk:
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https://journals.sag...
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http://kipublication...
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https://doi.org/10.1...
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Abstract
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- To identify determinants within 3 different domains (ie, somatic comorbidities, cognitive functioning, and neuropsychiatric symptoms [NPS]) of health-related quality of life (HRQoL) over time in memory clinic patients without dementia. Methods: This longitudinal multicenter cohort study with a 3-year observation period recruited 315 individuals (age: 69.8 ± 8.6, 64.4% males, Mini-Mental State Examination score 26.9 ± 2.6). A multivariable explanatory model was built using linear mixed effects models (forward selection per domain) to select determinants for self-perceived HRQoL over time, as measured by the EuroQoL-5D visual analogue scale (EQ VAS). Results: Mean HRQoL at study entry was 69.4 ± 15.6. The presence of agitation, appetite and eating abnormalities, and eyes/ears/nose (ie, sensory impairment) comorbidities were associated with a change in HRQoL over time. Agitation was most strongly associated with HRQoL over time. Conclusions: The association of somatic comorbidities and NPS in memory clinic patients with course of HRQoL shows that these should receive more awareness, detection, and monitoring by clinicians.
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- Av författaren/redakt...
-
Banning, LCP
-
Janssen, EPCJ
-
Hamel, REG
-
de Vugt, M
-
Kohler, S
-
Wolfs, CAG
-
visa fler...
-
Oosterveld, SM
-
Melis, RJF
-
Rikkert, MGMO
-
Kessels, RPC
-
Pijnenburg, YAL
-
Koene, T
-
van der Flier, W ...
-
Scheltens, P
-
Visser, PJ
-
Verhey, FRJ
-
Aalten, P
-
Ramakers, IHGB
-
visa färre...
- Artiklar i publikationen
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Journal of geria ...
- Av lärosätet
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Karolinska Institutet