Sökning: onr:"swepub:oai:prod.swepub.kib.ki.se:151170555" > Urine volume as an ...
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000 | 02772naa a2200301 4500 | |
001 | oai:prod.swepub.kib.ki.se:151170555 | |
003 | SwePub | |
008 | 240811s2022 | |||||||||||000 ||eng| | |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1511705552 URI |
024 | 7 | a https://doi.org/10.1038/s41598-022-23093-02 DOI |
040 | a (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Pinto, J4 aut |
245 | 1 0 | a Urine volume as an estimator of residual renal clearance and urinary removal of solutes in patients undergoing peritoneal dialysis |
264 | c 2022-11-05 | |
264 | 1 | b Springer Science and Business Media LLC,c 2022 |
520 | a In non-anuric patients undergoing peritoneal dialysis (PD), residual kidney function (RKF) is a main contributor to fluid and solute removal and an independent predictor of survival. We investigated if urine volume could be used to estimate renal clearances and removal of urea, creatinine, and phosphorus in PD patients. The observational, cross-sectional study included 93 non-anuric prevalent PD patients undergoing continuous ambulatory PD (CAPD; n = 34) or automated PD (APD; n = 59). Concentrations of urea, creatinine and phosphorus in serum and in 24-h collections of urine volume were measured to calculate weekly residual renal clearance (L/week) and removed solute mass (g/week). Median [interquartile range], 24-h urine output was 560 [330–950] mL and measured GFR (the mean of creatinine and urea clearances) was 3.24 [1.47–5.67] mL/min. For urea, creatinine and phosphorus, residual renal clearance was 20.60 [11.49–35.79], 43.02 [19.13–75.48] and 17.50 [8.34–33.58] L/week, respectively, with no significant differences between CAPD and APD. Urine volume correlated positively with removed solute masses (rho = 0.82, 0.67 and 0.74) and with weekly residual renal clearances (rho = 0.77, 0.62 and 0.72 for urea, creatinine, and phosphorus, respectively, all p < 0.001). Residual renal clearances and urinary mass removal rates for urea, creatinine, and phosphorus correlate strongly with 24-h urine volume suggesting that urine volume could serve as an estimator of typical values of residual solute removal indices in PD patients. | |
700 | 1 | a Debowska, M4 aut |
700 | 1 | a Gomez, R4 aut |
700 | 1 | a Waniewski, J4 aut |
700 | 1 | a Lindholm, Bu Karolinska Institutet4 aut |
710 | 2 | a Karolinska Institutet4 org |
773 | 0 | t Scientific reportsd : Springer Science and Business Media LLCg 12:1, s. 18755-q 12:1<18755-x 2045-2322 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:151170555 |
856 | 4 8 | u https://doi.org/10.1038/s41598-022-23093-0 |
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