Sökning: onr:"swepub:oai:prod.swepub.kib.ki.se:1928845" > Neuroimaging findin...
Fältnamn | Indikatorer | Metadata |
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000 | 02109naa a2200349 4500 | |
001 | oai:prod.swepub.kib.ki.se:1928845 | |
003 | SwePub | |
008 | 240902s1999 | |||||||||||000 ||eng| | |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:19288452 URI |
024 | 7 | a https://doi.org/10.1159/0000170972 DOI |
040 | a (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Pedersen, NLu Karolinska Institutet4 aut |
245 | 1 0 | a Neuroimaging findings in twins discordant for Alzheimer's disease |
264 | c 1998-12-18 | |
264 | 1 | b S. Karger AG,c 1999 |
520 | a Data from computed tomography (CT) scans of 12 twin pairs in which one partner had Azheimer’s disease (AD) and the other partner is cognitively intact were analyzed to study structural brain features associated with AD while controlling for familial factors. Visual ratings and analysis of quantified areas and volumes indicated that AD twins showed more dilation of temporal horns, lateral ventricles and third ventricle, and more atrophy of temporal lobes, particularly in the anterior temporal/perisylvian area, than their healthy cotwins. Demented twins did not have smaller intracranial areas or overall brain volumes than their intact partners. The apolipoprotein σ-4 allele was associated with greater dilation of lateral ventricles and ventricular volume. Significant intrapair correlations were found for total intracranial area and volume, cerebellar area and white matter lesions. | |
700 | 1 | a Miller, BL4 aut |
700 | 1 | a Wetherell, JL4 aut |
700 | 1 | a Vallo, J4 aut |
700 | 1 | a Toga, AW4 aut |
700 | 1 | a Knutson, N4 aut |
700 | 1 | a Mehringer, CM4 aut |
700 | 1 | a Small, GW4 aut |
700 | 1 | a Gatz, M4 aut |
710 | 2 | a Karolinska Institutet4 org |
773 | 0 | t Dementia and geriatric cognitive disordersd : S. Karger AGg 10:1, s. 51-58q 10:1<51-58x 1420-8008x 1421-9824 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:1928845 |
856 | 4 8 | u https://doi.org/10.1159/000017097 |
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