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FältnamnIndikatorerMetadata
00002545naa a2200301 4500
001oai:prod.swepub.kib.ki.se:1929935
003SwePub
008240913s1999 | |||||||||||000 ||eng|
024a http://kipublications.ki.se/Default.aspx?queryparsed=id:19299352 URI
024a https://doi.org/10.3109/028418599091755952 DOI
040 a (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Einarsdottir, H4 aut
2451 0a 110 subfascial lipomatous tumors. MR and CT findings versus histopathological diagnosis and cytogenetic analysis
264 c 2016-08-30
264 1b SAGE Publications,c 1999
520 a Purpose: To evaluate whether liposarcoma, atypical lipomatous tumors and lipoma can be differentiated radiologically. Material and Methods: We have retrospectively analyzed CT and/or MR images of 110 subfascial lipomatous lesions. the amount of fat within the tumors was visually graded from the images as: none, 1–75%, 75–95% or 95–100%. the structure of non-fatty tumor components was compared. the images were compared to histopathology and in 37 cases to cytogenetic findings. Results: Only 4 of 20 liposarcomas contained fat. All 4 lesions, histopathologically diagnosed as atypical lipomatous tumors, contained fat but less than 75% of tumor volume. All lesions with more fat than 75% of tumor volume were histologically diagnosed as lipomas. However, one-third of the karyotyped lipomas had ring chromosomes which are considered typical for atypical lipomatous tumors. Conclusion: When a tumor is composed more or less solely of fat, the diagnosis of a lipoma or atypical lipomatous tumor with a phenotype simulating a lipoma can be assumed. When the fat content is less than 75% of the tumor volume or non-fatty nodules are found, biopsies from different tumor components have to be performed to exclude malignancy. When no fat is found, imaging does not help in differentiating lipoma or liposarcoma from other soft tissue tumors.
700a Soderlund, V4 aut
700a Larsson, Ou Karolinska Institutet4 aut
700a Mandahl, N4 aut
700a Bauer, HCFu Karolinska Institutet4 aut
710a Karolinska Institutet4 org
773t Acta radiologica (Stockholm, Sweden : 1987)d : SAGE Publicationsg 40:6, s. 603-609q 40:6<603-609x 0284-1851x 1600-0455
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:1929935
8564 8u https://doi.org/10.3109/02841859909175595

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