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Real-world data on ...
Real-world data on treatment concepts in classical Hodgkin lymphoma in Sweden 2000-2014, focusing on patients aged >60 years
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- Wahlin, Björn Engelbrekt (författare)
- Division of Haematology, Department of Medicine, Huddinge, Karolinska Institutet, Stockholm, Sweden; Haematology unit, Karolinska University Hospital, Stockholm, Sweden
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- Övergaard, Ninja (författare)
- Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden
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- Peterson, Stefan (författare)
- Regional Cancer Center South, Lund, Sweden
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- Digkas, Evangelos (författare)
- Department of Oncology, Mälarsjukhuset, Eskilstuna, Sweden
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- Glimelius, Ingrid (författare)
- Karolinska Institutet,Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden
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- Lagerlöf, Ingemar (författare)
- Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden; Department of Haematology, University Hospital of Linköping, Linköping, Sweden
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- Johansson, Ann Sofie (författare)
- Umeå universitet,Onkologi
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- Palma, Marzia (författare)
- Karolinska Institutet,Haematology unit, Karolinska University Hospital, Stockholm, Sweden
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- Hansson, Lotta (författare)
- Karolinska Institutet,Haematology unit, Karolinska University Hospital, Stockholm, Sweden
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- Linderoth, Johan (författare)
- Department of Oncology, Lund University, Lund, Sweden
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- Goldkuhl, Christina (författare)
- Department of Oncology, Sahlgrenska University Hospital, Gothenburg, Sweden
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- Molin, Daniel (författare)
- Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden
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(creator_code:org_t)
- 2021-05-06
- 2021
- Engelska.
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Ingår i: eJHaem. - : John Wiley & Sons. - 2688-6146. ; 2:3, s. 400-412
- Relaterad länk:
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https://doi.org/10.1...
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https://umu.diva-por... (primary) (Raw object)
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Treatment for patients > 60 years with classical Hodgkin lymphoma (cHL) is problematic; there is no gold standard, and outcome is poor. Using the Swedish Lymphoma Registry, we analysed all Swedish patients diagnosed with cHL between 2000 and 2014 (N = 2345; median age 42 years; 691 patients were >60 years). The median follow-up time was 6.7 years. Treatment for elderly patients consisted mainly of ABVD or CHOP, and the younger patients were treated with ABVD or BEACOPP (with no survival difference). In multivariable analysis of patients > 60 years, ABVD correlated with better survival than CHOP (p = 0.027), and ABVD became more common over time among patients aged 61-70 years (p = 0.0206). Coinciding with the implementation of FDG-PET/CT, the fraction of advanced-stage disease increased in later calendar periods, also in the older patient group. Survival has improved in cHL patients > 60 years (p = 0.027), for whom ABVD seems superior to CHOP.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Hematologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Hematology (hsv//eng)
Nyckelord
- classical Hodgkin lymphoma
- older patients
- population-based
- survival
- treatment
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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eJHaem
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Till lärosätets databas
- Av författaren/redakt...
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Wahlin, Björn En ...
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Övergaard, Ninja
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Peterson, Stefan
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Digkas, Evangelo ...
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Glimelius, Ingri ...
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Lagerlöf, Ingema ...
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visa fler...
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Johansson, Ann S ...
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Palma, Marzia
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Hansson, Lotta
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Linderoth, Johan
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Goldkuhl, Christ ...
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Molin, Daniel
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visa färre...
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- MEDICIN OCH HÄLSOVETENSKAP
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eJHaem
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Umeå universitet
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Karolinska Institutet