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Protein-coated nano...
Protein-coated nanostructured surfaces affect the adhesion of Escherichia coli
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- Kallas, Pawel (författare)
- Universitetet i Oslo,University of Oslo
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Valen, Hakon (författare)
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- Hulander, Mats, 1974 (författare)
- Chalmers tekniska högskola,Chalmers University of Technology
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- Gadegaard, Nikolaj (författare)
- University of Glasgow
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- Stormonth-Darling, John (författare)
- University of Glasgow
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O'Reilly, Padraic (författare)
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- Thiede, Bernd (författare)
- Universitetet i Oslo,University of Oslo
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- Andersson, Martin, 1974 (författare)
- Chalmers tekniska högskola,Chalmers University of Technology
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- Haugen, Havard J. (författare)
- Universitetet i Oslo,University of Oslo
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(creator_code:org_t)
- 2022
- 2022
- Engelska.
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Ingår i: Nanoscale. - : Royal Society of Chemistry (RSC). - 2040-3372 .- 2040-3364. ; 14:20, s. 7736-7746
- Relaterad länk:
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https://research.cha... (primary) (free)
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https://research.cha...
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https://doi.org/10.1...
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Abstract
Ämnesord
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- Developing new implant surfaces with anti-adhesion bacterial properties used for medical devices remains a challenge. Here we describe a novel study investigating nanotopography influences on bacterial adhesion on surfaces with controlled interspatial nanopillar distances. The surfaces were coated with proteins (fibrinogen, collagen, serum and saliva) prior to E. coli-WT adhesion under flow conditions. PiFM provided chemical mapping and showed that proteins adsorbed both between and onto the nanopillars with a preference for areas between the nanopillars. E. coli-WT adhered least to protein-coated areas with low surface nanopillar coverage, most to surfaces coated with saliva, while human serum led to the lowest adhesion. Protein-coated nanostructured surfaces affected the adhesion of E. coli-WT.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinsk bioteknologi -- Biomaterialvetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Medical Biotechnology -- Biomaterials Science (hsv//eng)
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Medicinsk material- och protesteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Medical Materials (hsv//eng)
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- ref (ämneskategori)
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