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Sustained release o...
Sustained release of nucleic acids from polymeric nanoparticles using microemulsion precipitation in supercritical carbon dioxide
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- Ge, J. (författare)
- Stanford University
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- Jacobson, G. B. (författare)
- Stanford University
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- Lobovkina, Tatsiana, 1975 (författare)
- Stanford University
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- Holmberg, Krister, 1946 (författare)
- Chalmers tekniska högskola,Chalmers University of Technology
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- Zare, R. N. (författare)
- Stanford University
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(creator_code:org_t)
- Royal Society of Chemistry (RSC), 2010
- 2010
- Engelska.
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Ingår i: Chemical Communications. - : Royal Society of Chemistry (RSC). - 1364-548X .- 1359-7345. ; 46:47, s. 9034-9036
- Relaterad länk:
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http://dx.doi.org/10...
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https://doi.org/10.1...
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https://research.cha...
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Abstract
Ämnesord
Stäng
- A general approach for producing biodegradable nanoparticles for sustained nucleic acid release is presented. The nanoparticles are produced by precipitating a water-in-oil microemulsion in supercritical CO2. The microemulsion consists of a transfer RNA aqueous solution (water phase), dichloromethane containing poly(L-lactic acid)-poly(ethylene glycol) (oil phase), the surfactant n-octyl beta-D-glucopyranoside, and the cosurfactant n-butanol.
Ämnesord
- NATURVETENSKAP -- Kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences (hsv//eng)
Nyckelord
- rna
- emulsions
- interference
- microspheres
- in-vivo
- mechanism
- sirna
- delivery
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
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