Sökning: onr:"swepub:oai:research.chalmers.se:34118b41-f093-4769-b1c1-8cc495f17c9c" >
Analysis of clinica...
Analysis of clinical data to determine the minimum number of sensors required for adequate skin temperature monitoring of superficial hyperthermia treatments
-
- Bakker, A. (författare)
- Universiteit Van Amsterdam,University of Amsterdam
-
- Holman, Rebecca (författare)
- Universiteit Van Amsterdam,University of Amsterdam
-
Rodrigues, Dario B. (författare)
-
visa fler...
-
- Dobsicek Trefna, Hana, 1979 (författare)
- Chalmers tekniska högskola,Chalmers University of Technology
-
Stauffer, P. R. (författare)
-
- van Tienhoven, Geertjan (författare)
- Universiteit Van Amsterdam,University of Amsterdam
-
- Rasch, Coen R.N. (författare)
- Universiteit Van Amsterdam,University of Amsterdam
-
- Crezee, Hans (författare)
- Universiteit Van Amsterdam,University of Amsterdam
-
visa färre...
-
(creator_code:org_t)
- 2018-04-27
- 2018
- Engelska.
-
Ingår i: International Journal of Hyperthermia. - : Informa UK Limited. - 0265-6736 .- 1464-5157. ; 34:7, s. 910-917
- Relaterad länk:
-
https://research.cha... (primary) (free)
-
visa fler...
-
https://jdc.jefferso...
-
https://doi.org/10.1...
-
https://research.cha...
-
visa färre...
Abstract
Ämnesord
Stäng
- Purpose: Tumor response and treatment toxicity are related to minimum and maximum tissue temperatures during hyperthermia, respectively. Using a large set of clinical data, we analyzed the number of sensors required to adequately monitor skin temperature during superficial hyperthermia treatment of breast cancer patients. Methods: Hyperthermia treatments monitored with >60 stationary temperature sensors were selected from a database of patients with recurrent breast cancer treated with re-irradiation (23 × 2 Gy) and hyperthermia using single 434 MHz applicators (effective field size 351–396 cm2). Reduced temperature monitoring schemes involved randomly selected subsets of stationary skin sensors, and another subset simulating continuous thermal mapping of the skin. Temperature differences (ΔT) between subsets and complete sets of sensors were evaluated in terms of overall minimum (Tmin) and maximum (Tmax) temperature, as well as T90 and T10. Results: Eighty patients were included yielding a total of 400 hyperthermia sessions. Median ΔT was 50 sensors were used. Subsets of 50 sensors were used. Thermal profiles (8–21 probes) yielded a median ΔT < 0.01 °C for T90 and Tmax, with a 95%CI of −0.2 °C and 0.4 °C, respectively. The detection rate of Tmax≥43 °C is ≥85% while using >50 stationary sensors or thermal profiles. Conclusions: Adequate coverage of the skin temperature distribution during superficial hyperthermia treatment requires the use of >50 stationary sensors per 400 cm2applicator. Thermal mapping is a valid alternative.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Medicinsk laboratorie- och mätteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Medical Laboratory and Measurements Technologies (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- radiation therapy
- quality assurance
- thermal dosimetry
- temperature monitoring
- Hyperthermia
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
Hitta via bibliotek
Till lärosätets databas