Sökning: onr:"swepub:oai:research.chalmers.se:4e789c87-de58-432b-992c-d799e40729ed" > Effect of self-demo...
Fältnamn | Indikatorer | Metadata |
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000 | 03907naa a2200517 4500 | |
001 | oai:research.chalmers.se:4e789c87-de58-432b-992c-d799e40729ed | |
003 | SwePub | |
008 | 171008s2012 | |||||||||||000 ||eng| | |
024 | 7 | a https://doi.org/10.1088/0031-9155/57/12/36752 DOI |
024 | 7 | a https://research.chalmers.se/publication/1604732 URI |
040 | a (SwePub)cth | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Daeichin, Verya,d 1984u Chalmers tekniska högskola,Chalmers University of Technology4 aut0 (Swepub:cth)verya |
245 | 1 0 | a Effect of self-demodulation on the subharmonic response of contrast agent microbubbles |
264 | c 2012-05-22 | |
264 | 1 | b IOP Publishing,c 2012 |
520 | a Subharmonic (SH) emission from the ultrasound contrast agent (UCA) is of interest since it is produced only by the UCA and not by tissue, opposite to harmonic imaging modes where both tissue and microbubble show harmonics. In this work, the use of the self-demodulation (S-D) signal as a means of microbubble excitation at the SH frequency to enhance the SH emission of UCA is studied. The S-D wave is a low-frequency signal produced by the weak nonlinear propagation of an ultrasound wave. It is proportional to the second time derivative of the squared envelope of the transmitted signal. A diluted population of BR14 UCA (Bracco Research SA, Geneva, Switzerland) was insonified by a 10 MHz transducer focused at 76 mm firing bursts with different envelopes, durations and peak pressure amplitudes. The center frequency of the S-D signal changes from low frequencies (around 0.5 MHz) toward the transmitted frequency (10 MHz) by modifying the envelope function from Gaussian to rectangular. For 6 and 20 transmitted cycles, the SH response is enhanced up to 25 and 22 dB, respectively, when using a rectangular envelope instead of a Gaussian one. The experimental results are confirmed by the numerical simulation. The effects of the excitation duration and pressure amplitude are also studied. This study shows that a suitable design of the envelope of the transmit excitation to generate a S-D signal at the SH frequency can enhance the SH emission of UCA, and the SH imaging is feasible at high frequencies with a shorter transmit burst (six-cycle) and low acoustic pressure (similar to 100 KPa). | |
650 | 7 | a TEKNIK OCH TEKNOLOGIERx Medicinteknik0 (SwePub)2062 hsv//swe |
650 | 7 | a ENGINEERING AND TECHNOLOGYx Medical Engineering0 (SwePub)2062 hsv//eng |
653 | a oscillations | |
653 | a ang ph | |
653 | a high-frequency ultrasound | |
653 | a encapsulated microbubbles | |
653 | a radial modulation | |
653 | a approximation | |
653 | a 1995 | |
653 | a excitation technique | |
653 | a generation | |
653 | a bubbles | |
653 | a driving pulse | |
653 | a intravascular | |
653 | a ieee transactions on ultrasonics ferroelectrics and frequency control | |
653 | a ultrasound | |
700 | 1 | a Faez, T.u Erasmus Universiteit Rotterdam,Erasmus University Rotterdam4 aut |
700 | 1 | a Renaud, G.u Erasmus Universiteit Rotterdam,Erasmus University Rotterdam4 aut |
700 | 1 | a Bosch, J.G.u Erasmus Universiteit Rotterdam,Erasmus University Rotterdam4 aut |
700 | 1 | a Van Der Steen, A.F.W.u Erasmus Universiteit Rotterdam,Erasmus University Rotterdam4 aut |
700 | 1 | a De Jong, N.u Erasmus Universiteit Rotterdam,Erasmus University Rotterdam4 aut |
710 | 2 | a Chalmers tekniska högskolab Erasmus Universiteit Rotterdam4 org |
773 | 0 | t Physics in Medicine and Biologyd : IOP Publishingg 57:12, s. 3675-3691q 57:12<3675-3691x 0031-9155x 1361-6560 |
856 | 4 | u http://dx.doi.org/10.1088/0031-9155/57/12/3675y FULLTEXT |
856 | 4 8 | u https://doi.org/10.1088/0031-9155/57/12/3675 |
856 | 4 8 | u https://research.chalmers.se/publication/160473 |
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