Sökning: onr:"swepub:oai:research.chalmers.se:7fb6c333-f610-489e-9d71-f3d9bc8801d4" >
Comparison of PHITS...
Comparison of PHITS, GEANT4, and HIBRAC simulations of depth-dependent yields of beta(+)-emitting nuclei during therapeutic particle irradiation to measured data
-
- Rohling, Heide (författare)
- Technische Universität Dresden
-
- Sihver, Lembit, 1962 (författare)
- Chalmers tekniska högskola,Chalmers University of Technology
-
- Priegnitz, Marlen (författare)
- Helmholtz Zentrum,Helmholtz Center
-
visa fler...
-
- Enghardt, Wolfgang (författare)
- Technische Universität Dresden,Helmholtz Zentrum,Helmholtz Center
-
- Fiedler, Fine (författare)
- Helmholtz Zentrum,Helmholtz Center
-
visa färre...
-
(creator_code:org_t)
- 2013-09-02
- 2013
- Engelska.
-
Ingår i: Physics in Medicine and Biology. - : IOP Publishing. - 0031-9155 .- 1361-6560. ; 58:18, s. 6355-6368
- Relaterad länk:
-
http://dx.doi.org/10...
-
visa fler...
-
https://doi.org/10.1...
-
https://research.cha...
-
visa färre...
Abstract
Ämnesord
Stäng
- For quality assurance in particle therapy, a non-invasive, in vivo range verification is highly desired. Particle therapy positron-emission-tomography (PT-PET) is the only clinically proven method up to now for this purpose. It makes use of the beta(+)-activity produced during the irradiation by the nuclear fragmentation processes between the therapeutic beam and the irradiated tissue. Since a direct comparison of beta(+)-activity and dose is not feasible, a simulation of the expected beta(+)-activity distribution is required. For this reason it is essential to have a quantitatively reliable code for the simulation of the yields of the beta(+)-emitting nuclei at every position of the beam path. In this paper results of the three-dimensional Monte-Carlo simulation codes PHITS, GEANT4, and the one-dimensional deterministic simulation code HIBRAC are compared to measurements of the yields of the most abundant beta(+)-emitting nuclei for carbon, lithium, helium, and proton beams. In general, PHITS underestimates the yields of positron-emitters. With GEANT4 the overall most accurate results are obtained. HIBRAC and GEANT4 provide comparable results for carbon and proton beams. HIBRAC is considered as a good candidate for the implementation to clinical routine PT-PET.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
Nyckelord
- IN-BEAM PET
- ACCURATE UNIVERSAL PARAMETERIZATION
- PROTON THERAPY
- RELATIVISTIC HEAVY-IONS
- DISTRIBUTIONS
- ABSORPTION CROSS-SECTIONS
- MONTE-CARLO CALCULATION
- FRAGMENT-PRODUCTION
- CARBON-ION THERAPY
- INDUCED BETA(+)-ACTIVITY
Publikations- och innehållstyp
- art (ämneskategori)
- ref (ämneskategori)
Hitta via bibliotek
Till lärosätets databas