Surface adsorption of fibronectin-derived peptide fragments: the influence of electrostatics and hydrophobicity for endothelial cells adhesion

• The adsorption on hydrophobic and hydrophilic silica-based surfaces of the integrin-binding PHSRN peptide and the single-residual-mutated analogues, PHSEN and PHSFN, is investigated by comparative QCM-D, XPS, SFG measurements and molecular dynamics calculations. Endothelial cell cultures on the peptide-functionalized materials highlight their tunable pro- or anti-angiogenic potential.

Ämnesord

NATURVETENSKAP  -- Kemi (hsv//swe)

NATURAL SCIENCES  -- Chemical Sciences (hsv//eng)

Nyckelord

molecules

sum-frequency generation

monolayers

interfaces

Publikations- och innehållstyp

art (ämneskategori)

ref (ämneskategori)