Sökning: onr:"swepub:oai:slubar.slu.se:40604" > A Genome-Wide Assoc...
Fältnamn | Indikatorer | Metadata |
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000 | 04051naa a2200409 4500 | |
001 | oai:slubar.slu.se:40604 | |
003 | SwePub | |
008 | 240910s2013 | |||||||||||000 ||eng| | |
024 | 7 | a https://res.slu.se/id/publ/406042 URI |
024 | 7 | a https://doi.org/10.1371/journal.pone.00535252 DOI |
040 | a (SwePub)slu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Dalman, Kerstinu Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för skoglig mykologi och patologi,Department of Forest Mycology and Pathology4 aut0 (Swepub:slu)46883 |
245 | 1 0 | a A Genome-Wide Association Study Identifies Genomic Regions for Virulence in the Non-Model Organism Heterobasidion annosum ss |
264 | c 2013-01-16 | |
264 | 1 | b Public Library of Science (PLoS),c 2013 |
264 | 1 | b Public Library of Science,c 2024 |
520 | a The dense single nucleotide polymorphisms (SNP) panels needed for genome wide association (GWA) studies have hitherto been expensive to establish and use on non-model organisms. To overcome this, we used a next generation sequencing approach to both establish SNPs and to determine genotypes. We conducted a GWA study on a fungal species, analysing the virulence of Heterobasidion annosum s.s., a necrotrophic pathogen, on its hosts Picea abies and Pinus sylvestris. From a set of 33,018 single nucleotide polymorphisms (SNP) in 23 haploid isolates, twelve SNP markers distributed on seven contigs were associated with virulence (P,0.0001). Four of the contigs harbour known virulence genes from other fungal pathogens and the remaining three harbour novel candidate genes. Two contigs link closely to virulence regions recognized previously by QTL mapping in the congeneric hybrid H. irregulare6H. occidentale. Our study demonstrates the efficiency of GWA studies for dissecting important complex traits of small populations of non-model haploid organisms with small genomes. | |
650 | 7 | a NATURVETENSKAPx Biologix Genetik0 (SwePub)106092 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Biological Sciencesx Genetics0 (SwePub)106092 hsv//eng |
650 | 7 | a LANTBRUKSVETENSKAPERx Lantbruksvetenskap, skogsbruk och fiskex Skogsvetenskap0 (SwePub)401042 hsv//swe |
650 | 7 | a AGRICULTURAL SCIENCESx Agriculture, Forestry and Fisheriesx Forest Science0 (SwePub)401042 hsv//eng |
700 | 1 | a Himmelstrand, Kajsau Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för skoglig mykologi och patologi,Department of Forest Mycology and Pathology4 aut0 (Swepub:slu)48968 |
700 | 1 | a Olson, Åkeu Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för skoglig mykologi och patologi,Department of Forest Mycology and Pathology4 aut0 (Swepub:slu)50517 |
700 | 1 | a Lind, Mårtenu Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Department of Forest Mycology and Plant Pathology4 aut0 (Swepub:slu)48620 |
700 | 1 | a Brandström Durling, Mikaelu Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för skoglig mykologi och patologi,Department of Forest Mycology and Pathology4 aut0 (Swepub:slu)49619 |
700 | 1 | a Stenlid, Janu Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för skoglig mykologi och patologi,Department of Forest Mycology and Pathology4 aut0 (Swepub:slu)46689 |
710 | 2 | a Sveriges lantbruksuniversitetb Institutionen för skoglig mykologi och patologi4 org |
710 | 2 | a Sveriges lantbruksuniversitet |
773 | 0 | t PLoS ONEd : Public Library of Science (PLoS)g 8, s. 1-10q 8<1-10x 1932-6203 |
856 | 4 | u https://pub.epsilon.slu.se/id/eprint/10755/contentsx primaryx Raw objectx freey FULLTEXT |
856 | 4 | u https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0053525&type=printable |
856 | 4 8 | u https://res.slu.se/id/publ/40604 |
856 | 4 8 | u https://doi.org/10.1371/journal.pone.0053525 |
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