| 1. |
- Hamideh, J., et al.
(author)
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Karyotypic studies of three Thymus (Lamiaceae) species and populations in Iran
- 2009
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In: Caryologia (Firenze). - 0008-7114 .- 2165-5391. ; 62:4, s. 316-325
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Journal article (peer-reviewed)abstract
- Karyotypes of three taxa (seven populations) of the genus Thymus from different geographic origins is presented. The secondary basic numbers in all populations was x= 15 that probably originate from a basic number x=7.The ploidy levels were different among populations belongs to T. daenensis and T. kotschyanus species (2x and 4x). Detailed karyotype analysis allows us to group the different populations and to postulate relationships among them.
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| 2. |
- Heneen, Waheeb
(author)
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Two DVDs on “The Beauty of Mitosis”
- 2011
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In: Caryologia. - : Firenze University Press. - 0008-7114 .- 2165-5391. ; 64, s. 129-132
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Other publication (other academic/artistic)
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| 3. |
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| 4. |
- Smolarz, Katarzyna, et al.
(author)
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Histology, cytogenetics and cytofluorymetry in diagnosis of neoplasia in the Baltic clam Macoma balthica (Bivalvia, L.) from the Gulf of Gdansk (Baltic Sea)”.
- 2005
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In: Caryologia (Firenze). - 0008-7114 .- 2165-5391. ; 58:3, s. 212-219
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Journal article (peer-reviewed)abstract
- This study presents results of histopathologic, cytogenetics and flow cytometry analyses performed on Macoma balthica collected from the Gulf of Gdansk (Baltic Sea) in 2003 in order to compare the techniques for diagnosis of neoplasia. The proportion of affected clams gave a crude prevalence of 15.7 %. The four stages of the disease defined by histology and three stages of neoplasia defined by flow cytometry were reported. Stage I defined by flow cytometry corresponded to stages I and II defined by histology. Chromosome analysis did not lead to a staging of neoplastic progression. Both cytogenetics and flow cytometry indicated a difference in the DNA content of non-neoplastic and neoplastic cells. Cytogenetics examination marked that the range of chromosome numbers scored in abnormal mitosis corresponded to pentaploid-like cells (2.37 x diploid) and was similar to the mean DNA quantity identified using flow cytometry (2.36 x diploid). These methods generally have lower diagnosis sensitivity because with both techniques only a part of an animal can be studied. Thus, histology examination appeared to be the most sensitive tool for detection of the possible foci of neoplastic cells, metastasis and rare tumour cells freely circulating in the hemolymph in the early stages of the disease. Cytogenetic analysis has been considered as an important tool for the evaluation of aquatic environment quality as well as for the ecological risk assessment. Flow cytometry provided a rapid and easy method for discrimination of the aneuploid cells within thousands of cells per individual. Thus, in diagnosis of early stages of the cancer as well as early metastasis histology analyses should be performed. Chromosomes analysis and flow cytometry examination are important techniques for detection abnormalities in cell division, cell viability and DNA quantity. They appear to be very important in diagnosis of tumors based on high aneuploidy level
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| 5. |
- Antonio, L D, et al.
(author)
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The non-random location of human oncogenes and tumour suppressor genes
- 2005
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In: Caryologia. - 0008-7114. ; 58:1, s. 1-14
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Journal article (peer-reviewed)abstract
- We have analysed 994 sites for oncogenes and tumour suppressor genes located within human chromosome bands. The data presented disclose that: 1) These cancer genes build ridges as well as hot spots, which are not related to the position of other types of genes present in these chromosomes. 2) The frequency of cancer genes is not directly related to chromosome length, to the number of DNA bases per chromosome or to the number of structural genes present in each chromosome. 3) Suppressor genes tend to occupy the same location as oncogenes. 4) Several cancer genes occur in as many as 15 different sites spread over 10 different chromosomes. 5) The main feature of the distribution of both oncogenes and suppressors, is that they tend to be located near telomeres. Moreover, their numbers decrease from the telomere to the centromere building a distinct gradient. The difference is statistically significant. The present evidence, taken together, indicates that the telomeric territory might be a preferential location of cancer related genes and thereby also of stem cell genes.
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| 6. |
- Lima-De-faria, Antonio
(author)
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Comparison of the evolution of orchids with that of bats
- 2020
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In: Caryologia. - 0008-7114. ; 73:2, s. 51-61
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Journal article (peer-reviewed)abstract
- The evolution of orchids and bats is an example of DNA’s own evolution which has resulted in structures and functions which are not necessarily related to any obvious advantage to the organism. The flowers of orchids resemble: humans, apes, lizards, frogs and even shoes. The faces of bats resemble plant leaves but also horseshoes. These similarities are not accidental because they emerge repeatedly in different genera and different families. This evolutionary situation bewildered botanists and zoologists for many years, but is now elucidated by the molecular unification of plants and animals derived from the following evidence: (1) Contrary to expectation, plant and animal cells (including those of humans) could be fused and the human chromosomes were seen dividing in the plant cytoplasm. (2) Orchids, bats and humans have about the same number of genes: orchids, 21,841; bats, 21,237 and humans circa 20,000. (3) These three groups contain the same homeotic genes which decide: flower formation (orchids), body segmentation (bats) and body segmentation (humans). The leaf pattern, is formed in plants by the LEAFY master gene, but this pattern even appears in minerals, which have no genes, an indication that pure atomic processes are responsible for its emergence at the organism level.
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| 7. |
- Lima-De-faria, Antonio
(author)
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The chromosome resembles more a crystal than other cell organelles
- 2023
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In: Caryologia. - 0008-7114. ; 76:3, s. 3-7
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Journal article (peer-reviewed)abstract
- Several organelles in the cell, such as mitochondria and chloroplasts, are lim-ited by one or several membranes, whereas others, like ribosomes and nucleoli have no membranes. Their shape is decided by their inner atomic coherence. The mineral crystal has no delimiting membranes built by separate atoms. Atomic self-assembly deter-mines its pattern. Remarkable is that the chromosome has no outer membrane limiting its pattern as seen in the light and electronic microscopes. Its pattern is also decided by the inner coherence of the atomic configuration of its DNA, RNA, and proteins. The chromosome appears to occupy an intermediate position between a mineral crystal and a cell organelle when its atomic configuration is considered.
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