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1.	Grönkvist, Mikael J, et al. (author) Mechanisms of ventilation inhomogeneity during vital capacity breaths standing and supine 2002 In: Respiration Physiology. - 0034-5687 .- 1872-7611. ; 129:3, s. 345-355 Journal article (peer-reviewed)abstract Overall inhomogeneity of ventilation distribution, as measured by single-breath vital capacity (VC) washout (SBW) is known to be greater supine vs. standing. To establish the underlying mechanisms 13 healthy males performed VC SBW of 4% SF(6) and He, standing and supine, with or without a 10 sec breathhold (BH). Overall inhomogeneity, as indicated by normalized phase III slopes, was >50% greater supine (SF(6) 13.1 x 10(-3); He 10.7 x 10(-3) L(-1)) than standing (SF(6) 8.6 x 10(-3); He 6.4 x 10(-3) L(-1); P<0.001). The (SF(6)-He) slope, an index of intraacinar inhomogeneity, did not change with posture. Breathholding, assumed to eliminate convective dependent inhomogeneity within and/or between small lung units, produced twice as great reduction of inhomogeneity when supine vs. standing. After BH inhomogeneity remained significantly greater supine vs. standing. In conclusion, at least two events seem to underlie the increased inhomogeneity when supine: (1) a substantially increased convection dependent non-uniformity between well-separated lung regions; and (2) a somewhat increased convection dependent non-uniformity within and/or between peripherally located lung units.
2.	Artlich, A, et al. (author) Exhaled nitric oxide in preterm infants 1998 In: Respiration physiology. - : Elsevier BV. - 0034-5687. ; 114:2, s. 195-200 Journal article (peer-reviewed)
3.	Berggren, P, et al. (author) Computerized image analysis of lung expansion patterns in surfactant treated immature newborn rabbits 1999 In: Respiration physiology. - 0034-5687. ; 115:1, s. 45-53 Journal article (peer-reviewed)
4.	LEE, LY, et al. (author) Cigarette smoke-induced bronchoconstriction and release of tachykinins in guinea pig lungs 1995 In: Respiration physiology. - : Elsevier BV. - 0034-5687. ; 99:1, s. 173-181 Journal article (peer-reviewed)
5.	Wallin, CJB, et al. (author) Effects of rapid colloid volume expansion on pulmonary microvascular pressure and lung water in the conscious sheep 1997 In: Respiration physiology. - : Elsevier BV. - 0034-5687. ; 108:3, s. 225-231 Journal article (peer-reviewed)

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Type of publication: journal article (5)

Type of content: peer-reviewed (5)

Author/Editor: Lundberg, JM (1); Artlich, A (1); Hjelmqvist, H (1); Curstedt, T. (1); Eriksson, S. (1); Robertson, B (1); show more...; Rundgren, M (1); Berggren, P. (1); Busch, T (1); Lewandowski, K (1); Schaible, T (1); Falke, KJ (1); Gortner, L (1); Rigaut, JP (1); Gustafsson, Per M. (1); Grönkvist, Mikael J (1); Emery, Michael J. (1); LEE, LY (1); LOU, YP (1); HONG, JL (1); Leksell, LG (1); Wallin, CJB (1); show less...

University: Karolinska Institutet (4); Royal Institute of Technology (1); Linköping University (1)

Language: English (5)

Research subject (UKÄ/SCB): Medical and Health Sciences (1)

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