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- Cooper, L, et al.
(författare)
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Effect of post-brushing mouthwash solutions on salivary fluoride retention--study 2.
- 2012
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Ingår i: The Journal of clinical dentistry. - 0895-8831. ; 23:3, s. 92-6
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: This study evaluated the effects of three post-brushing mouthwashes containing 0 ppm F, 225 ppm F, and 500 ppm F, respectively, on salivary fluoride retention after brushing with 1450 ppm fluoride (as NaF) toothpaste and rinsing with water immediately after brushing. METHODS: In this three-phase, randomized, cross-over study, an ion-specific electrode was used to measure salivary F levels in thirty trial participants before brushing (Time 0), and after brushing, rinsing with water, and then rinsing with one of the three mouthwashes. Time points evaluated after brushing were one, three, five, 10, 20, 30, 45, and 60 minutes. For saliva sample collections, subjects were asked to pool saliva in their mouths for 10 seconds before spitting out into a container for each of the time points. RESULTS: The AUC0-60 means for F in saliva were 554, 252, and 20 for the 500, 225, and 0 ppm F mouthwash groups, respectively. The 500 ppm F mouthwash resulted in a 2660% increase in total fluoride salivary retention over 60 minutes when compared with the 0 ppm F group, and a 120% increase when compared with the 225 ppm F group. A significant difference (p < 0.001) in the AUC0-60 means between the three groups was observed using analysis of variance (ANOVA). Paired t-tests also showed significant differences in the mean fluoride retention over 60 minutes for all three pair-wise group comparisons (p < 0.001). CONCLUSION: Use of a fluoride mouthwash containing 225 ppm F or 500 ppm F produced a significant increase in salivary fluoride retention following brushing with a 1450 ppm F toothpaste and rinsing with water compared to rinsing without fluoride. The use of the 500 ppm F mouthwash may be of particular benefit to those at high caries risk.
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| 2. |
- Moberg Sköld, Ulla, 1948, et al.
(författare)
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Effect of post-brushing mouthwash solutions on salivary fluoride retention--study 1.
- 2012
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Ingår i: The Journal of clinical dentistry. - 0895-8831. ; 23:3, s. 97-100
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: The aim of the present study was to evaluate the effects on post-brushing salivary F retention of rinsing with mouthwashes containing either 500 or 225 ppm F compared to not rinsing. METHODS: The study was a randomized, investigator-blind, cross-over trial with three treatment arms. Thirty volunteers brushed with 0.5 g of 1450 ppm F paste for 40 seconds and then spat out the waste slurry. They then rinsed for one minute with 10 mL of their allocated mouthwash or they did not rinse after the brushing. Saliva samples were collected before brushing (0 minutes) and at one, three, five, 10, 20, 30, 45, and 60 minutes after brushing. The subjects were not allowed to speak, eat, or drink during these 60-minute test periods. The F levels in saliva were then calculated for each time point and the integrated area under the curve calculated (AUC0-60). RESULTS: The mean AUCs were 626, 380, and 237 for the 500 ppm F, 225 ppm F, and no rinse treatments, respectively, and all pair-wise comparisons were statistically significant (p < 0.01). CONCLUSION: It is concluded that rinsing with either 500 or 225 ppm F mouthwash significantly increases the level of F in saliva compared to not rinsing after brushing with 1450 ppm F toothpaste. The 500 ppm F mouthwash provided a significant increase in F retention compared to the 225 ppm F rinse (p = 0.001).
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| 3. |
- Ramberg, Per, 1949, et al.
(författare)
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The effect of a triclosan dentifrice on mucositis in subjects with dental implants: a six-month clinical study
- 2009
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Ingår i: Journal of Clinical Dentistry. - 0895-8831. ; 20:3, s. 103-7
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: The objective of the present clinical study was to assess the effect of the use of a dentifrice containing triclosan on peri-implant mucositis in subjects that had been restored with dental implants. METHODS: The trial was designed as a double-blind, randomized, two-treatment, parallel-group clinical study. Sixty male and female subjects, aged 30-70 years, were recruited. All subjects had lost teeth due to periodontal disease, and had been restored with a minimum of two implants at least one year prior to the start of the trial. Subjects were randomly assigned to two treatment groups. The subjects in the test group (Test) brushed their teeth and implant-supported restorations with a dentifrice containing triclosan, while the control subjects brushed with a sodium fluoride dentifrice. Only subjects with a minimum of one implant site showing clinical signs of peri-implant mucositis, i.e., bleeding after probing, were enrolled in the study. Clinical examinations were performed at baseline, and after three and six months. The following parameters were scored: Probing pocket depth (PPD), bleeding on probing (BoP), and plaque. The change from baseline within each treatment group at three months and six months was evaluated for all parameters using ANOVA and ANCOVA. RESULTS: Subjects with peri-implant mucositis who used a dentifrice containing 0.3% triclosan, as an adjunct to mechanical tooth brushing, exhibited significantly fewer clinical signs of inflammation than subjects who used a regular fluoride dentifrice at six months. The BoP scores were reduced from 53.8% to 29.1% in the Test group, whereas in the same interval there was an increase from 52.3% to 58.8% in the Control group. Furthermore, the individual mean PPD, as well as the frequency of sites with 5 mm and > or = 6 mm deep pockets, were reduced significantly more in the Test than in the Control group. CONCLUSION: The regular use of a dentifrice containing triclosan may reduce the clinical signs of inflammation in the mucosa adjacent to dental implants.
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