| 1. |
- Jakobsson, Ulf
(author)
-
Development and Psychometric Evaluation of the Pain Impact Inventory.
- 2009
-
In: Pain Practice. - : Wiley. - 1533-2500 .- 1530-7085. ; 9, s. 418-427
-
Journal article (peer-reviewed)abstract
- Abstract Objectives: The aim of this study was to develop and psychometrically evaluate an instrument for measuring the impact of chronic pain on daily life. Methods: The study comprised 384 respondents (aged between 18-102 years) who reported chronic pain. The instrument "Pain Impact Inventory" (PII) was evaluated in terms of face, content, construct and criterion validity, as well as two reliability measures. Reliability was measured by means of test-retest (with a 2-week interval) while Cronbach's alpha was used to measure internal consistency. Results: The results showed that the PII had acceptable validity and reliability. The PII contains 20 items and was found to have a nested design with five sub-scales (Physical impact, Psychological impact, Impact on social life, Social support, and Control) and two overarching dimensions ("Impact" and "Support"). Conclusions: The initial tests showed that the PII seems to be a psychometrically sound instrument for measuring the impact of pain on daily life from a multidimensional perspective.
|
|
| 2. |
- Jakobsson, Ulf, et al.
(author)
-
The Pain Impact Inventory-Further Validation in Various Subgroups.
- 2012
-
In: Pain Practice. - : Wiley. - 1533-2500 .- 1530-7085. ; 12, s. 350-356
-
Journal article (peer-reviewed)abstract
- Objectives: The aim of the study was to further psychometrically evaluate the instrument "Pain Impact Inventory" (PII) in various subgroups. Methods: The sample comprised 384 persons (aged between 18 and 102 years) who reported chronic pain. The instrument PII was evaluated in terms of construct validity as well as reliability. The instrument's validity was investigated through corrected item-total correlation, floor and ceiling effects, and item response rate. Reliability was assessed by means of test-retest (with a 2-week interval) and Cronbach's alpha. All analyses were performed in various subgroups, men and women, as well as in 6 different age-groups and 5 primary pain location. Results: The result showed an item-total correlation above 0.30 for all items in all subgroups with exception for the 2 items in F5 in the age-group, 30 to 44. In the test-retest analysis, all kappa coefficients in the test-retest analysis were significant (P < 0.001) and varied between 0.482 and 0.879. The alpha values for factor 1 to 4 ranged between 0.80 and 0.94. Alpha values below 0.7 were only found for F5. Conclusion: The PII showed satisfactory psychometric properties in terms of construct validity and reliability with regard to gender, age-groups, and primary pain location.
|
|
| 3. |
- Busch, Hillevi, et al.
(author)
-
Self-efficacy beliefs predict sustained long-term sick absenteeism in individuals with chronic musculoskeletal pain
- 2007
-
In: Pain Practice. - : Wiley. - 1530-7085 .- 1533-2500. ; 7:3, s. 234-240
-
Journal article (peer-reviewed)abstract
- Recovery beliefs are assumed to predict rehabilitation outcomes and return-to-work in various clinical conditions but are less frequently assessed in musculoskeletal disorders. We tested the hypothesis that recovery beliefs constitute a risk factor for sustained long-term sick absenteeism in men and women suffering from nonspecific chronic musculoskeletal disorders. A total of 233 subjects with a recent or ongoing experience of long-term sick leave were included in a prospective design. Subjects answered a postal baseline questionnaire and were followed up via register data for 1 year. Multivariate logistic regression analyses indicated that subjects with negative recovery beliefs (OR: 2.41; CI: 1.22–4.77), low sense of mastery (OR: 2.08; CI: 1.27–3.40), perceived high mental demands at work (OR: 1.77; CI: 1.05–2.99), and prior experiences of long-term sick absenteeism (OR: 1.86; CI: 1.02–3.37) had an increased probability of receiving sickness benefits at follow-up. We conclude that prolonged sickness absence contributes strongly to increase patients' sense of helplessness, lower self-efficacy, and hinder future work return. To improve work return, patients' maladaptive beliefs should be clarified and challenged early in the rehabilitation process.
|
|
| 4. |
- Busch, Hillevi, et al.
(author)
-
Visuospatial and verbal memory in chronic pain patients: an explorative study.
- 2006
-
In: Pain Practice. - : Wiley. - 1530-7085 .- 1533-2500. ; 6:3, s. 179-185
-
Journal article (peer-reviewed)abstract
- Cognitive bias, such as selective memory for pain-related information, is frequently observed in chronic pain patients and is assessed mostly using verbal material. Beside word lists, the current study used photographs of people presenting pain behaviours to assess memory bias in chronic pain patients. Chronic pain patients were hypothesized to show better recall of pain-related words and pictures as compared to pain-free controls. Twenty-eight female chronic neck patients and 28 pain-free female controls completed two computerized pictorial memory games and two word recall tasks. Patients and controls performed equally well in the neutral memory game. In the pain-related game, patients performed significantly worse than did controls. No significant differences were found in the word recall task. The result is discussed in terms of cognitive avoidance.
|
|
| 5. |
|
|
| 6. |
- Bjurstrom, M. F., et al.
(author)
-
Decreased pain sensitivity and alterations of cerebrospinal fluid and plasma inflammatory mediators after total hip arthroplasty in patients with disabling osteoarthritis
- 2022
-
In: Pain Pract. - : Wiley. - 1533-2500 .- 1530-7085. ; 22:1, s. 66-82
-
Journal article (peer-reviewed)abstract
- BACKGROUND: Proinflammatory mechanisms are implicated in pain states. Recent research indicates that patients with osteoarthritis (OA) with signs of central sensitization exhibit elevated cerebrospinal fluid (CSF) levels of interferon gamma-induced protein 10 (IP-10), Fms-related tyrosine kinase 1 (Flt-1), and monocyte chemoattractant protein 1 (MCP-1). METHODS: The current prospective cohort study, including 15 patients with OA, primarily aimed to evaluate associations among alterations in CSF IP-10, Flt-1, MCP-1, and pain sensitization following total hip arthroplasty (THA). Participants provided CSF and blood samples for analysis of 10 proinflammatory mediators, and underwent detailed clinical examination and quantitative sensory testing, immediately preoperative and 18 months after surgery. RESULTS: Neurophysiological measures of pain showed markedly reduced pain sensitivity long-term postoperative. Increases in remote site pressure pain detection thresholds (PPDTs) and decreased temporal summation indicated partial resolution of previous central sensitization. Compared to preoperative, CSF concentrations of IP-10 were increased (p = 0.041), whereas neither Flt-1 (p = 0.112) nor MCP-1 levels changed (p = 0.650). Compared to preoperative, plasma concentrations of IP-10 were increased (p = 0.006), whereas interleukin (IL)-8 was decreased (p = 0.023). Subjects who exhibited increases in arm PPDTs above median showed greater increases in CSF IP-10 compared to those with PPDT increases below median (p = 0.028). Analyses of plasma IP-10 and IL-8 indicated higher levels of peripheral inflammation were linked to decreased pressure pain thresholds (unadjusted beta = -0.79, p = 0.006, and beta = -118.1, p = 0.014, respectively). CONCLUSIONS: THA leads to long-term decreases in pain sensitivity, indicative of resolution of sensitization processes. Changes in CSF and plasma levels of IP-10, and plasma IL-8, may be associated with altered pain phenotype.
|
|
| 7. |
- Bjurstrom, M. F., et al.
(author)
-
Perioperative Pharmacological Sleep-Promotion and Pain Control : A Systematic Review
- 2019
-
In: Pain Pract. - : Wiley. - 1530-7085 .- 1533-2500. ; 19:5, s. 552-569
-
Journal article (peer-reviewed)abstract
- BACKGROUND: Sleep macrostructure is commonly disturbed after surgery. Postoperative pain control remains challenging. Given the bidirectional interaction between sleep and pain, understanding the role of modulation of sleep during the perioperative period on postoperative pain is needed. METHODS: This was a systematic review. Controlled trials examining the effects of perioperative sleep-promoting pharmacological agents on postoperative pain and analgesic consumption were identified through a systematic search strategy utilizing multiple electronic databases. RESULTS: Fourteen studies (9 melatonin, 5 zolpidem) involving 921 patients (melatonin n = 586, zolpidem n = 335) were included. Compared to placebo, melatonin reduced postoperative pain scores by >/=30% and significantly decreased opioid consumption in 3 studies (postoperative day [POD] 1-2), whereas 4 studies reported no significant effect of melatonin on postoperative pain. Compared to placebo, zolpidem reduced postoperative pain scores during POD1-7/POD1-14 in 2 studies, but only 1 trial suggested clinically meaningful improvement (ie, relative reduction of pain score >/= 30%). Whereas 3 zolpidem trials showed no significant differences regarding postoperative pain ratings, zolpidem treatment was associated with decreased analgesic consumption in 4 out of 5 trials. Several limitations of the included studies were identified; only 1 study out of 14 was deemed to be at low risk of bias, and heterogeneity of the study design and outcome assessment precluded meta-analysis. CONCLUSION: Perioperative addition of a sleep-promoting pharmacological agent may improve pain control, but underlying evidence is weak and results are inconsistent. Only 5 of the 14 studies objectively evaluated changes in sleep (polysomnography, 2 zolpidem studies; actigraphy, 3 melatonin studies), which complicates conclusions regarding links between perioperative sleep and pain.
|
|
| 8. |
|
|
| 9. |
- Fernandez-de-las-Penas, C., et al.
(author)
-
Sensitization symptoms are associated with psychological and cognitive variables in COVID-19 survivors exhibiting post-COVID pain
- 2023
-
In: Pain Practice. - : Wiley. - 1530-7085 .- 1533-2500. ; 23:1, s. 23-31
-
Journal article (peer-reviewed)abstract
- Objective To investigate the association between demographic, clinical, psychological, cognitive, and health-related variables and the Central Sensitization Inventory (CSI) in previously hospitalized COVID-19 survivors exhibiting "de novo" post-COVID pain. Methods Seventy-seven (n = 77) COVID-19 survivors with "de novo" post-COVID pain completed demographic (age, height, and weight), clinical (duration and intensity of the pain), psychological (depressive/anxiety levels and sleep quality), cognitive (catastrophizing and kinesiophobia levels), and health-related quality of life variables as well as the CSI. A multivariable correlation analysis was conducted to determine the association between variables, and a stepwise multiple linear regression model was performed to identify CSI predictors. Results Patients were assessed a mean of 6.0 (SD 0.8) months after hospital discharge. Twenty-six (33.7%) individuals showed indications of sensitization-associated symptoms (CSI score >= 40 points). The CSI score was positively associated with pain intensity (r: 0.371), anxiety (r: 0.784), depressive (r: 0.709), catastrophizing (r: 0.620), and kinesiophobia (r: 0.359) levels (all, p < 0.001). The stepwise regression analysis revealed that 60.2% of CSI was explained by anxiety levels and pain intensity. Conclusion This study found that psychological and cognitive variables were associated with the CSI score in previously hospitalized COVID-19 survivors with "de novo" post-COVID pain. Anxiety levels and the intensity of pain symptoms were independently associated with CSI score suggesting a significant overlap with psychological construct. The "de novo" post-COVID pain association with CSI may indicate changes in the pain processing important for managing the pain.
|
|
| 10. |
- Fullen, Brona, et al.
(author)
-
Management of Chronic Low Back Pain and the Impact on Patients' Personal and Professional Lives : Results From an International Patient Survey
- 2022
-
In: Pain Practice. - : Wiley-Blackwell Publishing Inc.. - 1530-7085 .- 1533-2500. ; 22:4, s. 463-477
-
Journal article (peer-reviewed)abstract
- OBJECTIVE: The objective of this study was to investigate the impact of chronic low back pain (CLBP) on patients' personal and professional lives, and management strategies applied to treat CLBP.METHODS: A 60-question survey was developed and respondents from 16 countries with a self-reported physician's diagnosis of CLBP were recruited via an online market research survey panel. Respondents were stratified as having mild, moderate, or severe pain. Target sample sizes per country and for pain severity were set. Data were weighted according to the known population and prevalence of CLBP in each country, and the number of respondents from that country.RESULTS: Results from 9,642 CLBP patients indicated that almost a quarter of patients with severe CLBP report a psychological comorbidity. Prescription pain medications were more commonly used by patients with severe CLBP (56%) than those with mild (20%) or moderate (34%) CLBP. Among those with severe CLBP who had been prescribed pain medication, 58% were prescribed opioids, with 1 in 4 patients using opioids for more than 5 years. Patients were primarily managed by general practitioners/primary care physicians, physiotherapists, neurologists, or orthopedic surgeons. CLBP negatively impacted patients' daily activities, social lives, and work productivity.CONCLUSION: CLBP has pronounced effects on patients' personal relationships, ability to work, and daily living. Almost 1 in 4 patients with severe CLBP reported a psychological comorbidity. Adherence to guidelines appears inconsistent, which is noteworthy as a substantial subgroup of patients with severe CLBP had been prescribed opioid medication for more than 5 years. Improved education is required to support healthcare professionals (HCPs) in identifying and understanding the complex biopsychosocial needs of CLBP patients to optimize pain management, and to encourage referral of CLBP patients to physiotherapists and psychologists.
|
|
