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- Ambrosio, Fabrisia, et al.
(author)
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The effect of muscle loading on skeletal muscle regenerative potential : an update of current research findings relating to aging and neuromuscular pathology
- 2009
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In: American Journal of Physical Medicine & Rehabilitation. - Baltimore : Lippincott Williams & Wilkins. - 0894-9115 .- 1537-7385. ; 88:2, s. 145-155
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Research review (peer-reviewed)abstract
- Skeletal muscle is a dynamic tissue with a remarkable ability to continuously respond to environmental stimuli. Among its adaptive responses is the widely investigated ability of skeletal muscle to regenerate after loading or injury or both. Although significant basic science efforts have been dedicated to better understand the underlying mechanism controlling skeletal muscle regeneration, there has been relatively little impact in the clinical approaches used to treat skeletal muscle injuries and wasting. The purpose of this review article is to provide an overview of the basic biology of satellite cell function in response to muscle loading and to relate these findings in the context of aging and neuromuscular pathology for the rehabilitation medicine specialist.
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- Borg, David N, et al.
(author)
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Bicycling and tricycling road race performance in international para-cycling events between 2011 and 2019.
- 2022
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In: American Journal of Physical Medicine & Rehabilitation. - : Lippincott Williams & Wilkins. - 0894-9115 .- 1537-7385. ; 101:4, s. 384-388
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Journal article (peer-reviewed)abstract
- ABSTRACT: This study described bicycling (C-classes) and tricycling (T-classes) performance in International Cycling Federation road race events between 2011 and 2019. A total of 3,243 race results from 33 events were analyzed. Race velocity was calculated for each result. Bicycling and tricycling data were separately modelled using a linear mixed-effects model. Bicycling velocity was statistically different between all adjacent men's classes (Cohen's d = 0.14 to 0.73), and between the women's C1 and C2 (d = 1.15), and C3 and C4 (d = 0.48) classes. The absence of statistical differences between some women's bicycling classes may be due to a limited number of observations in these classifications. As expected, velocity was statistically different between men's (d = 1.64) and women's (d = 1.38) T1 and T2 classes. Road race performance was hierarchical within the disciplines of bicycling and tricycling, although not all adjacent women's bicycling classes were statistically different. The existence of a performance hierarchy does not necessarily validate the classification system. The integration of information regarding athlete impairment type and severity, with performance data, would provide greater insight into the validity of the classification system, and should be prioritized as an area of future research.
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- Godbolt, Alison K., et al.
(author)
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Opportunity for Inpatient Brain Injury Rehabilitation for Persons in a Vegetative State Survey of Swedish Physicians
- 2011
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In: American Journal of Physical Medicine & Rehabilitation. - 0894-9115 .- 1537-7385. ; 90:6, s. 482-489
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Journal article (peer-reviewed)abstract
- Objective: The aim of this study was to document physicians' opinions on inpatient rehabilitation care for working-age patients in vegetative state after new acquired brain injury, given the absence of an established standard of post-acute care. Design: A postal survey of 3259 Swedish physicians was conducted. Results: Survey response rate was 33%. Of survey respondents, 51% reported that they knew the definition of vegetative state. Transfer of vegetative patients from acute care to inpatient rehabilitation was considered always warranted by 54% and never or only sometimes warranted by 31% of survey respondents, whereas 15% did not know or did not answer. Rehabilitation physicians most often considered an inpatient rehabilitation stay of around 3 mos to be appropriate, but there was a lack of consensus. Discharge from acute care direct to social care at least sometimes was reported by 39% of physicians. Conclusions: Physicians' opinions vary considerably on appropriate post-acute care for patients in vegetative state after acquired brain injury. This may impact on rates of referral and admission to rehabilitation units. Consensus is needed on a minimum period for and extent of rehabilitation interventions. Educational interventions should be targeted broadly to reach the wide range of specialties that may have responsibility for acute care of these patients.
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| 7. |
- Granlund, Mats, et al.
(author)
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Differentiating activity and participation of children and youth with disability in Sweden : a third qualifier in the International Classification of Functioning, Disability, and Health for Children and Youth?
- 2012
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In: American Journal of Physical Medicine & Rehabilitation. - 0894-9115 .- 1537-7385. ; 91:13:S1, s. S84-S96
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Journal article (peer-reviewed)abstract
- OBJECTIVE:This article discusses the use of a third qualifier, subjective experience of involvement, as a supplement to the qualifiers of capacity and performance, to anchor activity and participation as separate endpoints on a continuum of actions.DESIGN:Empirical data from correlational studies were used for secondary analyses. The analyses were focused on the conceptual roots of the participation construct as indicated by the focus of policy documents, the support for a third qualifier as indicated by correlational data, differences between self-ratings and ratings by others in measuring subjective experience of involvement, and the empirical support for a split between activity and participation in different domains of the activity and participation component.RESULTS:Participation seems to have two conceptual roots, one sociologic and one psychologic. The correlational pattern between the qualifiers of capacity, performance, and subjective experience of involvement indicates a possible split between activity and participation. Self-ratings of participation provide information not obtained through ratings by others, and later domains in the activities and participation component fit better with measures of experienced involvement than earlier domains did.CONCLUSIONS:The results from secondary analyses provide preliminary support for the use of a third qualifier measuring subjective experience of involvement to facilitate the split between activity and participation in the International Classification of Functioning, Disability and Health, Children and Youth version, activity and participation domain.
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| 8. |
- Hill, Mattias, et al.
(author)
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The Swedish SPinal Cord Injury Study on Cardiopulmonary and Autonomic Impairment (SPICA) : Methodology, Cohort Demographics and Initial Results
- 2020
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In: American Journal of Physical Medicine and Rehabilitation. - 1537-7385. ; 99:6, s. 522-531
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Journal article (peer-reviewed)abstract
- OBJECTIVE: To present the methodology, cohort demographics and initial results of the Swedish SPinal Cord Injury Study on Cardiopulmonary and Autonomic Impairment (SPICA).DESIGN: SPICA is based on the Swedish Cardiopulmonary and Bioimage Study (SCAPIS), a study on cardiopulmonary diseases in a cohort of 30 000 people. The assessments in SPICA cover the structure and function of the cardiopulmonary and autonomic systems using bioimaging and functional analyses, together with a study-specific questionnaire and generic and SCI-specific assessment tools. The inclusion criteria were: age 50-65 years, traumatic SCI ≥5 years, injury levels C1-T6, American Spinal Injury Association Impairment Scale A-C.RESULTS: Of 38 potential participants, 25 comprised the final sample (20% women, mean age 58 years, mean time since injury 28 years). Eight percent had sustained a cardiovascular event, and 72% were classified as a high risk for cardiovascular disease (CVD). Asthma was previously diagnosed in only 8% and none had chronic obstructive pulmonary disease.CONCLUSION: The risk for CVD in people with severe high-level SCI is a major clinical concern. Forthcoming studies in SPICA will provide new knowledge of cardiopulmonary health in this cohort, which can guide future research and be used to develop long-term management.
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