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1.	Hällberg, B Martin, et al. (author) Making proteins in the powerhouse 2014 In: Cell Metabolism. - Stockholm : Karolinska Institutet, Dept of Cell and Molecular Biology. - 1550-4131 .- 1932-7420. Journal article (peer-reviewed)abstract Understanding regulation of mitochondrial DNA (mtDNA) expression is of considerable interest as mitochondrial dysfunction is important in human pathology and ageing. Similar to the situation in bacteria, there is no compartmentalization between transcription and translation in mitochondria; hence, both processes are likely to have a direct molecular crosstalk. Accumulating evidence suggests that there are important mechanisms for regulation of mammalian mtDNA expression at the posttranscriptional level. Regulation of mRNA maturation, mRNA stability, translational coordination, ribosomal biogenesis and translation itself, all form the basis for controlling oxidative phosphorylation capacity. Consequently, a wide variety of inherited human mitochondrial diseases are caused by mutations of nuclear genes regulating various aspects of mitochondrial translation. Furthermore, mutations of mtDNA, associated with human disease and ageing, often affect tRNA genes critical for mitochondrial translation. Recent advances in molecular understanding of mitochondrial translation regulation will likely provide novel avenues for modulating mitochondrial function to treat human disease.
2.	Abdulreda, MH, et al. (author) Liraglutide Compromises Pancreatic β Cell Function in a Humanized Mouse Model 2016 In: Cell metabolism. - : Elsevier BV. - 1932-7420 .- 1550-4131. ; 23:3, s. 541-546 Journal article (peer-reviewed)
3.	Agudelo, LZ, et al. (author) Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation 2018 In: Cell metabolism. - : Elsevier BV. - 1932-7420 .- 1550-4131. ; 27:2, s. 378- Journal article (peer-reviewed)
4.	Ahlqvist, KJ, et al. (author) Somatic progenitor cell vulnerability to mitochondrial DNA mutagenesis underlies progeroid phenotypes in Polg mutator mice 2012 In: Cell metabolism. - : Elsevier BV. - 1932-7420 .- 1550-4131. ; 15:1, s. 100-109 Journal article (peer-reviewed)
5.	Akerman, Ildem, et al. (author) Human Pancreatic β Cell lncRNAs Control Cell-Specific Regulatory Networks 2017 In: Cell Metabolism. - : Elsevier BV. - 1550-4131. ; 25:2, s. 400-411 Journal article (peer-reviewed)abstract Recent studies have uncovered thousands of long non-coding RNAs (lncRNAs) in human pancreatic β cells. β cell lncRNAs are often cell type specific and exhibit dynamic regulation during differentiation or upon changing glucose concentrations. Although these features hint at a role of lncRNAs in β cell gene regulation and diabetes, the function of β cell lncRNAs remains largely unknown. In this study, we investigated the function of β cell-specific lncRNAs and transcription factors using transcript knockdowns and co-expression network analysis. This revealed lncRNAs that function in concert with transcription factors to regulate β cell-specific transcriptional networks. We further demonstrate that the lncRNA PLUTO affects local 3D chromatin structure and transcription of PDX1, encoding a key β cell transcription factor, and that both PLUTO and PDX1 are downregulated in islets from donors with type 2 diabetes or impaired glucose tolerance. These results implicate lncRNAs in the regulation of β cell-specific transcription factor networks.
6.	Andersson, O, et al. (author) Adenosine signaling promotes regeneration of pancreatic β cells in vivo 2012 In: Cell metabolism. - : Elsevier BV. - 1932-7420 .- 1550-4131. ; 15:6, s. 885-894 Journal article (peer-reviewed)
7.	Angelin, B, et al. (author) Circulating fibroblast growth factors as metabolic regulators--a critical appraisal 2012 In: Cell metabolism. - : Elsevier BV. - 1932-7420 .- 1550-4131. ; 16:6, s. 693-705 Journal article (peer-reviewed)
8.	Angelin, B (author) Telling the liver (not) to make bile acids: a new voice from the gut? 2005 In: Cell metabolism. - : Elsevier BV. - 1550-4131. ; 2:4, s. 209-210 Journal article (peer-reviewed)
9.	Arner, P, et al. (author) Weight Gain and Impaired Glucose Metabolism in Women Are Predicted by Inefficient Subcutaneous Fat Cell Lipolysis 2018 In: Cell metabolism. - : Elsevier BV. - 1932-7420 .- 1550-4131. ; 28:1, s. 45- Journal article (peer-reviewed)
10.	Backdahl, J, et al. (author) Spatial mapping reveals human adipocyte subpopulations with distinct sensitivities to insulin 2021 In: Cell metabolism. - : Elsevier BV. - 1932-7420 .- 1550-4131. ; 33:11, s. 2301-2301 Journal article (other academic/artistic)

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Type of publication: journal article (184); research review (5); conference paper (1)

Type of content: peer-reviewed (180); other academic/artistic (10)

Author/Editor: Zierath, JR (17); Bäckhed, Fredrik, 19 ... (15); Larsson, NG (13); Berggren, PO (9); Renström, Erik (9); Cannon, Barbara (8); show more...; Nedergaard, Jan (8); Groop, Leif (7); Kroemer, G (6); Enerbäck, Sven, 1958 (6); Salehi, S Albert (5); Nielsen, Jens B, 196 ... (5); Krook, A (5); Ryden, M (5); Mardinoglu, Adil, 19 ... (5); Barres, R (5); Marschall, Hanns-Ulr ... (4); Tremaroli, Valentina ... (4); Caicedo, A (4); Arner, P (4); Borén, Jan, 1963 (4); Gao, H. (4); Trifunovic, A (4); Wibom, R (4); Eliasson, Lena (4); Krus, Ulrika (4); Larsson, Nils-Göran (4); Smith, Ulf, 1943 (4); Larsson, O (3); Madeo, F (3); Lyssenko, Valeriya (3); Abdulreda, MH (3); Ricordi, C (3); Rodriguez-Diaz, R (3); Angelin, B (3); Rorsman, Patrik, 195 ... (3); Mulder, Hindrik (3); Blom, Anna (3); Taneera, Jalal (3); Rosengren, Anders (3); Vikman, Petter (3); Wahlström, Annika, 1 ... (3); Ståhlman, Marcus, 19 ... (3); Rudling, M (3); Laakso, M. (3); Cao, Yihai (3); Clement, K (3); Perkins, Rosie, 1965 (3); Dahlman, I (3); Mejhert, N (3); show less...

University: Karolinska Institutet (105); University of Gothenburg (43); Lund University (24); Uppsala University (16); Stockholm University (12); Royal Institute of Technology (8); show more...; Chalmers University of Technology (8); Umeå University (7); Linköping University (4); Swedish University of Agricultural Sciences (4); Örebro University (2); The Swedish School of Sport and Health Sciences (2); show less...

Language: English (190)

Research subject (UKÄ/SCB): Medical and Health Sciences (83); Natural sciences (29); Agricultural Sciences (3)

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