| 1. |
- Andersson, Gerhard, 1966-, et al.
(författare)
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Are coping strategies really useful for the tinnitus patient? An investigation conducted via the internet
- 2004
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Ingår i: Audiological Medicine. - : Informa UK Limited. - 1651-386X .- 1651-3835. ; 2:1, s. 54-59
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Tidskriftsartikel (refereegranskat)abstract
- This questionnaire study investigated the role of coping strategies in tinnitus. The Tinnitus Coping Strategy Questionnaire (12) was administered via the internet to a sample of 157 persons with tinnitus who were recruited for participation in a treatment trial. Also included were the Tinnitus Reaction Questionnaire, the Anxiety Sensitivity Index, and the Hospital Anxiety and Depression Scale. Results showed a significant positive correlation between use of coping strategies and tinnitus distress, even when controlling for anxiety sensitivity, and anxiety and depression levels in a multiple regression analysis. In line with previous studies, the role of coping strategies is not uniformly positive for tinnitus patients, and might even be associated with increased distress. Treatment implications are discussed and a possible role of acceptance strategies is put forward.
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| 2. |
- Andersson, Gerhard, 1966-, et al.
(författare)
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Mixed feelings about living with tinnitus : A qualitative study
- 2008
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Ingår i: Audiological Medicine. - : Informa UK Limited. - 1651-386X .- 1651-3835. ; 6:1, s. 48-54
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Tidskriftsartikel (refereegranskat)abstract
- The aim of this qualitative study was to interview a group of tinnitus patients (n = 7) who were or had been involved in psychological treatment for their tinnitus. Following semi-structured interviews all conversations were transcribed and later categorized using methods inspired by grounded theory. Results revealed a higher order concept labelled ‘Mixed feelings about living with tinnitus’. Three descriptive categories were derived: 1) Consequences; 2) Treatment experiences; and 3) Tinnitus identity. Results are discussed in relation to the literature on tinnitus, and the future application of qualitative methods in tinnitus research is encouraged.
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| 3. |
- Andersson, Gerhard, 1966-, et al.
(författare)
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Prediction of balance among patients with vestibular disturbance : Application of the match/mismatch model
- 2008
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Ingår i: Audiological Medicine. - : Informa UK Limited. - 1651-386X .- 1651-3835. ; 6:3, s. 176-183
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Tidskriftsartikel (refereegranskat)abstract
- The present study investigated the role of overprediction in patients with vestibular disorders. The study was set up to investigate if the match/mismatch model is applicable for vestibular disorders. This model suggests that a tendency to overestimate the subjective impact of aversive events exists, and that this is a common psychological phenomenon. A group of 20 patients with dizziness and 20 normal controls participated in the experiment. The first part of the experiment consisted of nine spontaneous predictions. During all trials, vibratory calf stimulation of 80 Hz was provided to affect balance. In the second part of the experiment each group was split (randomly assigned) into one overprediction and one underprediction group, who received either 40 or 100 Hz calf stimulation with the change occurring in the fourth trial. Body sway was measured by a force platform. Included also were self-report inventories and measures of predicted and experienced body sway and risk of losing balance. The results showed that the patients overpredicted the first trial to a lesser degree than the controls. In the control group a repeated measures effect was found, but not in the patient group. However, in terms of percentages of correct predictions both groups improved as the trials proceeded. Induced under- or over-prediction was obtained for perceived body sway, but not for the prediction of risk of losing balance, where the overprediction groups instead underpredicted. Body sway data did not result in any interactions, but controls became more stable over trials. Implications for the proposed link between vestibular dysfunction and panic disorder are discussed. © 2008 Informa UK Ltd. (Informa Healthcare, Taylor & Francis As).
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| 4. |
- Bergemalm, Per-Olof
(författare)
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Progress of sensorineural hearing loss after closed head injury : presence of autoantibodies
- 2004
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Ingår i: Audiological Medicine. - : Informa healthcare. - 1651-386X .- 1651-3835. ; 2:2, s. 92-99
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Tidskriftsartikel (refereegranskat)abstract
- Sensorineural hearing impairment is a common sequel to closed head injury (CHI). In most cases, the impairment subsides within the first post‐traumatic year; in some cases the impairment is permanent and in other cases there will be progress. In most cases the reason for progress is unknown. Substantial research has been carried out to ascertain the aetiology of sudden sensorineural hearing loss (SNHL) and Menière's disease. A number of studies have demonstrated the presence of antibodies against HSP 70 antigen in patients' sera. In accordance with this finding, autoimmunity as an aetiological factor for progressive SNHL has been proposed. There are reports indicating that trauma is a possible mechanism for eliciting an autoimmune response, and the aim of the present study is to study this mechanism. The question of sympathetic cochleolabyrinthitis is highlighted. Sera from 35 subjects with a history of closed head injury three to 13 years prior to the investigation were obtained for Western blot immunoassay in an attempt to identify HSP 70 antibodies. Twenty‐seven of the subjects demonstrated progress of a sensorineural hearing impairment after CHI. Two of 35, both with progress of a SNHL, demonstrated presence of anti‐HSP 70 antibodies. Therefore, a significant role of an HSP 70 related autoimmune mechanism for SNHL progress post CHI could not be confirmed in the present study. Nevertheless, the possible role of autoantibodies in individual cases cannot be ruled out, neither can the presence of other transitory autoimmune reactions after CHI. No conclusive evidence of sympathetic cochleolabyrinthitis was found.
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| 5. |
- Bjerlemo, Berit, et al.
(författare)
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Recovery after early vestibular rehabilitation in patients with acute unilateral vestibular loss
- 2006
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Ingår i: Audiological Medicine. - : Informa UK Limited. - 1651-386X .- 1651-3835. ; 4:3, s. 117-123
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Tidskriftsartikel (refereegranskat)abstract
- The aims of this study were to follow the recovery process, and explore the disease impact on sick leave in patients with acute unilateral vestibular loss (AUVL). Another aim was to investigate whether initial signs of nystagmus, caloric response, and subjective symptoms of vertigo could predict the return to work. Recovery was followed through the reduction in spontaneous and head-shaking nystagmus, evaluated by Video-Frenzel examination, and by caloric response/asymmetry and spontaneous nystagmus, evaluated by bithermal binaural caloric testing. Information regarding employment, sick leave and subjective symptoms of vertigo was collected using a questionnaire. Twenty-seven patients with AUVL participated in a physiotherapy training programme, starting within 48 h of disease onset. Four assessments were performed: at disease onset, in the acute stage, and after one and six months. In most patients a very rapid cessation of spontaneous nystagmus could be observed (14/27 at a median time of two days after disease onset, a further 10 patients after one month and the remaining three patients after six months). A more prolonged persistence of head shaking nystagmus was observed (24/27, 14/27 and 5/21 of the patients showed head-shaking nystagmus at the three assessments). Caloric asymmetry was normalized after six months in 11/27 patients. A positive and significant correlation was observed between long-lasting sick leave and caloric asymmetry, sense of unsteadiness when standing and walking and older age. Unsteadiness when standing and walking, as well as existence of spontaneous nystagmus, were also positively and significantly correlated with the degree of caloric asymmetry. Spontaneous or head-shaking nystagmus, caloric asymmetry and subjective vertigo at disease onset did not, however, predict sick leave after one or six months. Recovery was excellent in most of the patients.
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| 6. |
- C. Manchaiah, Vinaya K., 1983-, et al.
(författare)
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Information about the prognosis given to sudden-sensorineural hearing loss patients: Implications to 'patient journey' process
- 2012
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Ingår i: Audiological Medicine. - London, UK : Informa Healthcare. - 1651-386X .- 1651-3835. ; 10:3, s. 109-113
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Tidskriftsartikel (refereegranskat)abstract
- Objective: The aim of this short paper is to highlight the implications of information provision about prognosis given to sudden sensorineural hearing loss (SSNHL) patients. Method: Semi-structured interviews were conducted with four SSNHL patients to develop the patient journey model that is published in our previous paper (12). In this study the implications from general, ethical and legal perspectives about the information provision were considered (i.e. discussion with experts and the use of relevant literature). Results: Three out of four patients interviewed reported that their doctors (both general practitioners and ENT specialists) gave false hopes about prognosis. From the preliminary data it appears that there is considerable variability in the views expressed by patients about preference in information provision. However, this issue needs consideration as the information provided by professionals may have a serious impact on service provision and outcome. Conclusions: It is our view that even though, in some instances, it may appear that false hope provides short-term psychological benefit to patients, providing full and honest information is necessary for general (i.e. to facilitate patient journey process), ethical and legal reasons.
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| 7. |
- C. Manchaiah, Vinaya K., 1983-, et al.
(författare)
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Models to represent communication partners within the social networks of people with hearing impairment
- 2011
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Ingår i: Audiological Medicine. - : Informa UK Limited. - 1651-386X .- 1651-3835. ; 9:3, s. 103-109
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Tidskriftsartikel (refereegranskat)abstract
- Objective: People with hearing impairment have relatively smaller social networks than their normally hearing peers, and may experience more feelings of loneliness. The effects on the person with hearing impairment (PHI) can also impact on their communication partners (CPs). This report discusses the currently available model representing the CPs within the social network context of the PHI and proposes a new model. Study design: The ‘Communication Rings’ proposed and developed by the Ida Institute is discussed. We believe that this model is too simple to represent the complexity and dynamic nature of the CP's role in the life of the PHI and highlights the need for a new model. Results: We suggest that the model ‘Communication World’ based on the analogy of the solar system, may help overcome some of the problems identified. Clinical examples of how to apply this model and its usefulness in rehabilitation are presented. Conclusions: The expanded model could provide novel information, and provision of a visual representation will help CPs understand the problems of the PHI.
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| 8. |
- C. Manchaiah, Vinaya K., 1983-, et al.
(författare)
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The role of communication partners in the audiological enablement/rehabilitation of a person with hearing impairment : An overview
- 2012
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Ingår i: Audiological Medicine. - 1651-386X .- 1651-3835. ; 10:1, s. 21-30
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Tidskriftsartikel (refereegranskat)abstract
- Objective: Hearing impairment is known to have various effects upon both the person with hearing impairment (PHI) and their communication partners (CPs). In addition, CPs are reported to play an important role in making the decision to seek a consultation and the acceptance of intervention by the PHI. The overall aim of this paper is to provide a comprehensive overview of the role of the CP in the audiological enablement/rehabilitation of the PHI keeping clinical practice in focus. Method: A literature review was conducted using a number of resources including electronic databases, books and websites. Results: An overview of the literature was presented in the following sections: 1) Factors influencing the audiological enablement/rehabilitation of the PHI; 2) Effect of the PHI's hearing impairment on their CPs; 3) CPs’ influence on their PHI's audiological enablement/rehabilitation; 4) Positive experiences reported by CPs of the PHI; 5) Models to represent CPs within the social network context of the PHI; and 6) CP involvement in the audiological enablement/rehabilitation. This paper also identifies gaps in the literature and provides recommendations for further research. Conclusion: It is clear that involvement of the CP in the audiological enablement/rehabilitation can result in mutual advantages for both the PHI and their CPs.
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| 9. |
- Carlsson, Per Inge, et al.
(författare)
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The influence of genetic factors, smoking and cardiovascular disease on human noise susceptibility
- 2007
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Ingår i: Audiological Medicine. - : Informa UK Limited. - 1651-386X .- 1651-3835. ; 5:2, s. 82-91
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Tidskriftsartikel (refereegranskat)abstract
- Noise has a metabolic and mechanical effect on the inner ear and may therefore interfere with gap junction channels, thus disrupting the interaction between cells in the cochlea. Studies have shown that carriers of connexin mutations in genes involved in HI may have some disturbance in auditory function and may be more susceptible to damage caused by, e.g. noises. Furthermore, hair cell damage in the cochlea as a result of noise exposure can also be mediated by reactive oxygen species. Smoking in combination with elevated diastolic blood pressure and presence of the Raynaud's disease (white finger disease) seems to aggravate noise induced hearing loss (NIHL). In the present study we investigated whether interaction between connexin mutations (C26 and C30) alone, or in combination with genetic variability in the cochlear antioxidant system (GSTM1 deletion, GSTT1 deletion), could explain differences in human noise susceptibility. Furthermore, smoking habits and cardiovascular factors (hypertension, heart disease and white finger diseases) were correlated with noise susceptibility and interactions between genetic factors. Smoking and cardiovascular factors were analysed and correlated with the differences in noise susceptibility found in a Swedish noise-exposed population. The results revealed that smoking alone seems to increase noise susceptibility, and that null-genotypes for the GSTM1 gene in the protective antioxidant system, who smoke/have ever smoked had an additional risk for NIHL compared to those who do not smoke/have never smoked.
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| 10. |
- Carlsson, Per-Inge, 1959-, et al.
(författare)
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Variabillity in noise susceptibility in a Swedish population : the role of 35delG mutation in the Connexin 26 (GJB2) gene
- 2004
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Ingår i: Audiological Medicine. - : Informa UK Limited. - 1651-386X .- 1651-3835. ; 2:2, s. 123-130
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Tidskriftsartikel (refereegranskat)abstract
- Although it seems that genetic factors can influence individual susceptibility to noise, still very little is known about the genes or the mechanisms involved. The connexin 26 (Cx26) (GJB2) gene is of particular interest to study in relation to noise, since the gene encodes the gap junction protein Cx26. Noise has a metabolic and mechanical effect on the inner ear and may, therefore, interfere with gap junction channels. In order to investigate whether abnormally high susceptibility to noise induced hearing loss (NIHL) in humans is associated with the common 35delG mutation in the Cx26 gene, 1200 noise‐exposed workers were investigated in Sweden. Using a selection procedure based on audiometric analysis, noise exposure data and questionnaires, noise‐exposed workers were divided into two categories: noise susceptible and noise resistant. There was a correspondence in noise susceptibility between this noise‐exposed population and the international reference ISO Standard 1999. Blood samples were drawn from 245 highly selected male subjects (103 noise susceptible, 112 noise resistant and 30 randomized cases), and genomic DNA was analysed with respect to the Cx26 35delG mutation. The incidence of 35delG carriers among this cohort was determined by multiplex, allele‐specific PCR. Two of the 245 subjects (0.8% ‐ [95% confidence interval 0.1–2.9]) were found to be heterozygous carriers of the 35delG mutation, while the remaining 243 subjects were all non‐carriers. Both the heterozygous carriers were found in the noise susceptible group. Statistical evaluation of the results demonstrated no significant difference in carrier incidence between the noise susceptible and noise resistant individuals in our Swedish noise‐exposed population. In conclusion, there was no support for a major role of Cx26 35delG mutation in explaining the variability in noise susceptibility in this Swedish population.
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