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Search: L773:2240 2993

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1.
  • Abul-Kasim, Kasim, et al. (author)
  • Combined Clinical and Radiological Prognostic Model in Acute Ischemic Stroke
  • 2010
  • In: Acta Neurologica Belgica. - 2240-2993. ; 110:3, s. 239-245
  • Journal article (peer-reviewed)abstract
    • We sought to propose and test the validity of a comprehensive prognostic model in middle cerebral artery-stroke treated with Intravenous thrombolysis. A total of 127 consecutive patients (aged 70 +/- 12 years; 54% males) were included in this retrospective study. Variables included in our prognostic model were: NIHSS on admission (1-3 points), occurrence of hyperdense middle cerebral artery sign and early ischemic signs on baseline CT (1 point each). NIHSS at 24 hours (0-3 points), posttreatment hemorrhage (1 point), and infarct volume (0-4 points). The score range teas 1-13, with higher values suggest unfavorable prognosis. Our prognostic score was correlated with the modified Rankin scale (mRS) at 3 months after stroke [correlation coefficient of 0.62, P < 0.001] and can thus help early prediction of the functional outcome. Logistic regression showed that NIHSS at 24 hours and EICs on baseline CT were independent predictor of our prognostic score (adjusted odds ratio of 4.1 and 5). Adopting a cut-off value of prognostic score <= 3 for favorable prognosis and >= 7 for unfavorable prognosis helped to predict the need for institutionalization and the functional outcome with higher accuracy and predictive values compared with using scores only based on NIHSS.
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  • Abul-Kasim, Kasim, et al. (author)
  • Transient ischemic attack with deceptive presentation
  • 2009
  • In: Acta Neurologica Belgica. - 2240-2993. ; 109:4, s. 333-335
  • Journal article (peer-reviewed)abstract
    • A patient with an initial diagnosis of TIA presented with a deceptive course of events and unfavorable outcome. Only a non-enhanced brain CT was performed initially. Hemodynamic studies were clone later on and revealed internal carotid artery (ICA) dissection on CT-angiography and evidence of irreversible ischemic changes on perfusion studies indicating that the ischemic process presumably was ongoing since the initial ischemic episode. Efforts to define patients with TIA with risk of developing major stroke are ongoing. We hereby exhort for more effort to include hemodynamic studies as early as possible in the radiological work-up of TIA.
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4.
  • Chroni, Elisabeth, et al. (author)
  • Low vitamin D levels in healthy controls and patients with autoimmune neuromuscular disorders in Greece
  • 2016
  • In: Acta Neurologica Belgica. - : Springer Science and Business Media LLC. - 0300-9009 .- 2240-2993. ; 116:1, s. 57-63
  • Journal article (peer-reviewed)abstract
    • Normal autoimmune function is dependent on adequate levels of activated vitamin D, 25 hydroxy vitamin D [25(OH) D]. A recent study presented deficiency of 25(OH) D levels in Swedish MG patients. We aimed to study 25(OH) D levels in patients with MG and autoimmune polyneuropathies (PNP) at a southern latitude in Greece. Plasma levels of 25(OH) D were analyzed in Greek patients with MG (n = 19), immune-mediated PNP (N = 11) and in 30 Greek healthy age-and sex-matched controls. Ten MG patients received supplementation with vitamin D3. The MG Composite Score (MGC) and MG quality of life assessed disease severity in MG patients, whereas the INCAT Disability Scale assessed clinical features in the PNP patients. MG patients with and without vitamin D3 supplementation had higher 25(OH) D levels (mean 58.8 +/- 16.3 and 62.0 +/- 22.4 nmol/L, respectively) than PNP patients (mean 42.1 +/- 11.5 nmol/L, p = 0.01) and healthy controls (mean 45.7 +/- 13.8 nmol/L, p = 0.01). Plasma 25(OH) D levels was lower with age in all groups. There were no correlations between 25(OH) D and disease duration, MGC score, or INCAT score. Vitamin D deficiency was found in all Greek patient groups and healthy controls. Levels of 25(OH) D were higher in MG patients with as well as without vitamin D supplementation compared to healthy controls, whereas CIDP/GBS patients had levels similar to controls.
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5.
  • Edvardsson, Bengt, et al. (author)
  • Cluster headache and acute maxillary sinusitis.
  • 2013
  • In: Acta Neurologica Belgica. - : Springer Science and Business Media LLC. - 2240-2993 .- 0300-9009. ; 113:4, s. 535-536
  • Journal article (peer-reviewed)
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  • Kremer, Christine, et al. (author)
  • Reduction of flow velocities in patients with ischemic events in the middle cerebral artery--long-term follow-up with ultrasound.
  • 2011
  • In: Acta Neurologica Belgica. - 2240-2993. ; 111:2, s. 111-115
  • Journal article (peer-reviewed)abstract
    • Data concerning the persistent reduction of flow velocities measured by transcranial color-coded sonography (TCCS) in relation to the clinical and radiological outcome among patients with ischemic events in middle cerebral artery (MCA) territory is scarce. Patients with > or = 50% reduction of peak systolic velocities (PSV-MCA) as compared to the contralateral MCA were prospectively included in follow-up by TCCS (mean 404 days). Out of 849 patients with stroke admitted to our stroke unit, 25 patients showed reduced PSV-MCA and included in the analyses of this study. Ten (40%) survivors showed persistent reduction of PSV-MCA. None of the patients with normalized PSV-MCA suffered an ischemic event compared with three patients with persistent reduction of PSV-MCA (all had ipsilateral occlusion of the internal carotid artery caused by dissection). Patients with persistently reduced PSV-MCA exhibited significantly (Mann-Whitney test, p = 0.02) larger infarct volumes on CT (mean +/- SD 38 +/-50 cm3) compared to those with normalized PSV-MCA (6 +/- 7 cm3). The functional outcome were, however, similar in patients with normalized and those with persistently reduced PSV-MCA. We found that a relatively high percentage (40%) of patients suffered ischemic event in the MCA territory with initial reduction of flow velocity on TCCS showed persistent reduction on long term follow-up.
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