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- Gravé, Jan, et al.
(author)
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STUDIES OF EFFECTS OF GSM-900 MICROWAVE EXPOSURE ON DNA ”MICRONUCLEUS” FORMATION IN MICE
- 2012
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In: Acta Scientiarum Lundensia. - 1651-5013. ; 2012:002, s. 1-15
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Journal article (other academic/artistic)abstract
- Possible genotoxic effects of microwave exposure from GSM-900 mobile telephones have investigated with in vivo micronucleus assay of mouse erythrocytes from CBA mice and GFAP knockout mice. No significant change in the frequency of erythrocytes with micronuclei neither in the young (polychromatic PCE) or mature (normichromatic NCE) erythrocytes. There is, however, a tendency but not significant to increased MPCE in female mice after 35 days of exposure. There is a marked tendency to lower PCE-fraction in the exposed groups. When male and female is studied separately there is no significant difference. However, if the values are normalised to eliminate the sex-difference there is a significant lower fraction in the exposed mice. Another observation is lower weight of the exposed male. If normalised data for both sexes are pooled there is an almost significant difference (95% level) in weight. We found a less pronounced difference in the CBE mice than in the GFAP experiment. Thus genotype might play a role in microwave exposure. Differences in exposure time and number of controls in GFAP and CBA experiment might influence the results. We observe a moderate decrease of formation of new erythrocytes in the exposed animals. This might fit the tendency of lower weight in the exposed animals and might indicate a general decreased cell-proliferation in the exposed animals.
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