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- Thomas, HS, et al.
(author)
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- 2019
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swepub:Mat__t
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- Ademuyiwa, Adesoji O., et al.
(author)
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Determinants of morbidity and mortality following emergency abdominal surgery in children in low-income and middle-income countries
- 2016
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In: BMJ Global Health. - : BMJ Publishing Group Ltd. - 2059-7908. ; 1:4
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Journal article (peer-reviewed)abstract
- Background: Child health is a key priority on the global health agenda, yet the provision of essential and emergency surgery in children is patchy in resource-poor regions. This study was aimed to determine the mortality risk for emergency abdominal paediatric surgery in low-income countries globally.Methods: Multicentre, international, prospective, cohort study. Self-selected surgical units performing emergency abdominal surgery submitted prespecified data for consecutive children aged <16 years during a 2-week period between July and December 2014. The United Nation's Human Development Index (HDI) was used to stratify countries. The main outcome measure was 30-day postoperative mortality, analysed by multilevel logistic regression.Results: This study included 1409 patients from 253 centres in 43 countries; 282 children were under 2 years of age. Among them, 265 (18.8%) were from low-HDI, 450 (31.9%) from middle-HDI and 694 (49.3%) from high-HDI countries. The most common operations performed were appendectomy, small bowel resection, pyloromyotomy and correction of intussusception. After adjustment for patient and hospital risk factors, child mortality at 30 days was significantly higher in low-HDI (adjusted OR 7.14 (95% CI 2.52 to 20.23), p<0.001) and middle-HDI (4.42 (1.44 to 13.56), p=0.009) countries compared with high-HDI countries, translating to 40 excess deaths per 1000 procedures performed.Conclusions: Adjusted mortality in children following emergency abdominal surgery may be as high as 7 times greater in low-HDI and middle-HDI countries compared with high-HDI countries. Effective provision of emergency essential surgery should be a key priority for global child health agendas.
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- Mahdy, Nasser M., et al.
(author)
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Petrogenesis of U- and Mo-bearing A(2)-type granite of the Gattar batholith in the Arabian Nubian Shield, Northeastern Desert, Egypt : Evidence for the favorability of host rocks for the origin of associated ore deposits
- 2015
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In: Ore Geology Reviews. - : Elsevier BV. - 0169-1368 .- 1872-7360. ; 71, s. 57-81
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Journal article (peer-reviewed)abstract
- Hydrothermal ore deposits associated with granitic rocks are the result of combinations and series of successive processes, events and conditions in a magma system and at post-magmatic stage. The metal content of a granitic magma as well as fractional crystallization, metal-ligand complexation, emplacement mechanisms and tectonic processes influence the metal precipitation and content of a hydrothermal ore deposit. The present study of the Gattar batholith evaluates how these processes contribute to the generation of an ore deposit. Gattar batholith in the north Eastern Desert of Egypt as part of the northern region of the Arabian-Nubian Shield (ANS) is geographically, mineralogically and geochemically divided into two distinctive areas. The southern part mainly consists of syenogranite while the northern part is dominated by highly evolved alkali-feldspar granite. Uranium and Mo mineralization occurring here is mostly limited to the margin of the highly evolved alkali-feldspar granites. New U-Pb zircon geochronology within this study indicates an age of similar to 620-600 Ma, although high common Pb and discordant age data of many zircon grains reflect alteration by F-rich fluids. Some zircons with distinct older U/Pb ages were considered to be inherited from the wall rocks representing juvenile crust of the ANS. The two different granitic rocks are comagmatic in origin and have A-type characteristics generated by partial melting of lower juvenile crust of the ANS. Geochemical data are in good agreement with a magmatic origin of the alkali-feldspar granites, suggesting fractional crystallization of a syenogranitic source as the most favorable process of their formation. Petrography, geochemistry, and geochronology studies of the Gattar granites along with field observations provide evidence for multiple intrusions as a result of successive magma pulses with different chemical composition. This led to the formation of reverse zoning within the intrusive complex. This kind of magma emplacement promotes the escape of exsolved metal-bearing volatile-rich fluids into the boundary of the Hammamat Sedimentary Rocks (HSR) and Gattar granite at the northern part of the batholith. Build-up of volatiles is a common phenomenon in granitic rocks and typically results in enhanced contents of F, alkalis and ore metals released at subsolidus stage.
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