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Search: WFRF:(Albers R. I.)

  • Result 1-10 of 32
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  • Vogel, Jacob W., et al. (author)
  • Four distinct trajectories of tau deposition identified in Alzheimer’s disease
  • 2021
  • In: Nature Medicine. - : Springer Science and Business Media LLC. - 1078-8956 .- 1546-170X. ; 27:5, s. 871-881
  • Journal article (peer-reviewed)abstract
    • Alzheimer’s disease (AD) is characterized by the spread of tau pathology throughout the cerebral cortex. This spreading pattern was thought to be fairly consistent across individuals, although recent work has demonstrated substantial variability in the population with AD. Using tau-positron emission tomography scans from 1,612 individuals, we identified 4 distinct spatiotemporal trajectories of tau pathology, ranging in prevalence from 18 to 33%. We replicated previously described limbic-predominant and medial temporal lobe-sparing patterns, while also discovering posterior and lateral temporal patterns resembling atypical clinical variants of AD. These ‘subtypes’ were stable during longitudinal follow-up and were replicated in a separate sample using a different radiotracer. The subtypes presented with distinct demographic and cognitive profiles and differing longitudinal outcomes. Additionally, network diffusion models implied that pathology originates and spreads through distinct corticolimbic networks in the different subtypes. Together, our results suggest that variation in tau pathology is common and systematic, perhaps warranting a re-examination of the notion of ‘typical AD’ and a revisiting of tau pathological staging. © 2021, The Author(s), under exclusive licence to Springer Nature America, Inc.
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  • Polettini, M., et al. (author)
  • Decay studies in the A∼225 Po-Fr region from the DESPEC campaign at GSI in 2021
  • 2022
  • In: Il Nuovo Cimento. - : Società Italiana di Fisica. - 2037-4909. ; 45:5
  • Journal article (peer-reviewed)abstract
    • The HISPEC-DESPEC collaboration aims at investigating the structure of exotic nuclei formed in fragmentation reactions with decay spectroscopy measurements, as part of the FAIR Phase-0 campaign at GSI. This paper reports on first results of an experiment performed in spring 2021, with a focus on beta-decaystudies in the Po-Fr nuclei in the 220 < A <230 island of octupole deformation exploiting the DESPEC setup. Ion-beta correlations and fast-timing techniques are being employed, giving an insight into this difficult-to-reach region.
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  • Result 1-10 of 32
Type of publication
journal article (29)
other publication (1)
conference paper (1)
research review (1)
Type of content
peer-reviewed (30)
other academic/artistic (2)
Author/Editor
Kurz, N (6)
Kojouharov, I. (6)
Schaffner, H. (6)
Blazhev, A. (6)
Cox, D. M. (5)
Eberth, J. (5)
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Reiter, P. (5)
Wimmer, K. (5)
Albers, M. (5)
Sarmiento, L. G. (5)
Gutierrez, A. (4)
Ortega, FB (4)
Merino, G. (4)
Vardavas, C (4)
Freeman, A (4)
Garcia, E. (4)
Judson, D. (4)
Ferrari, M (4)
Larsson, M (4)
Papadakis, P. (4)
Uusitalo, J. (4)
Hall, G. (4)
Thomas, S (4)
De Henauw, S. (4)
Molnár, D. (4)
Moreno, LA (4)
Sjostrom, M (4)
Hess, H. (4)
Warr, N. (4)
Fahlander, Claes (4)
Zaccaria, M. (4)
Sanchez, MJ (4)
Masson, A. (4)
Broberg, A. (4)
Cederkäll, Joakim (4)
Navarro, P. (4)
Ruiz, JR (4)
Hagstromer, M (4)
Herzberg, R-D (4)
Khuyagbaatar, J. (4)
Krier, J. (4)
Schausten, B. (4)
Fredriksson, H (4)
Manios, Y (4)
De Bourdeaudhuij, I (4)
Kwak, L. (4)
Rizzo, N (4)
Jimenez-Pavon, D (4)
Artero, EG (4)
Castillo, MJ (4)
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University
Lund University (14)
Karolinska Institutet (13)
University of Gothenburg (4)
Stockholm University (3)
Umeå University (2)
Royal Institute of Technology (2)
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Luleå University of Technology (2)
Uppsala University (1)
Linköping University (1)
Stockholm School of Economics (1)
Linnaeus University (1)
RISE (1)
Högskolan Dalarna (1)
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Language
English (32)
Research subject (UKÄ/SCB)
Natural sciences (16)
Medical and Health Sciences (10)
Social Sciences (3)
Engineering and Technology (2)

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