| 1. |
- Bergemalm, Daniel, 1977-, et al.
(author)
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Systemic Inflammation in Preclinical Ulcerative Colitis
- 2021
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In: Gastroenterology. - : AGA Institute. - 0016-5085 .- 1528-0012. ; 161:5, s. 1526-1539.e9
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Journal article (peer-reviewed)abstract
- Background & Aims: Preclinical ulcerative colitis is poorly defined. We aimed to characterize the preclinical systemic inflammation in ulcerative colitis, using a comprehensive set of proteins.Methods: We obtained plasma samples biobanked from individuals who developed ulcerative colitis later in life (n = 72) and matched healthy controls (n = 140) within a population-based screening cohort. We measured 92 proteins related to inflammation using a proximity extension assay. The biologic relevance of these findings was validated in an inception cohort of patients with ulcerative colitis (n = 101) and healthy controls (n = 50). To examine the influence of genetic and environmental factors on these markers, a cohort of healthy twin siblings of patients with ulcerative colitis (n = 41) and matched healthy controls (n = 37) were explored.Results: Six proteins (MMP10, CXCL9, CCL11, SLAMF1, CXCL11 and MCP-1) were up-regulated (P < .05) in preclinical ulcerative colitis compared with controls based on both univariate and multivariable models. Ingenuity Pathway Analyses identified several potential key regulators, including interleukin-1β, tumor necrosis factor, interferon-gamma, oncostatin M, nuclear factor-κB, interleukin-6, and interleukin-4. For validation, we built a multivariable model to predict disease in the inception cohort. The model discriminated treatment-naïve patients with ulcerative colitis from controls with leave-one-out cross-validation (area under the curve = 0.92). Consistently, MMP10, CXCL9, CXCL11, and MCP-1, but not CCL11 and SLAMF1, were significantly up-regulated among the healthy twin siblings, even though their relative abundances seemed higher in incident ulcerative colitis.Conclusions: A set of inflammatory proteins are up-regulated several years before a diagnosis of ulcerative colitis. These proteins were highly predictive of an ulcerative colitis diagnosis, and some seemed to be up-regulated already at exposure to genetic and environmental risk factors.
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| 2. |
- Walker, P W, et al.
(author)
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Identification, Synthesis and Field Testing of (3Z,6Z,9Z)-3,6,9-Henicosatriene, a Second Bioactive Component of the Sex Pheromone of the Autumn Gum Moth, Mnesampela privata
- 2009
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In: Journal of Chemical Ecology. - : Springer Science and Business Media LLC. - 0098-0331 .- 1573-1561. ; 35:12, s. 1411-1422
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Journal article (peer-reviewed)abstract
- Abstract - The sex pheromone of Mnesampela privata, an endemic pest of Eucalyptus plantations in Australia, was previously identified as containing a single bioactive compound, (3Z,6Z,9Z)-3,6,9-nonadecatriene (C19 triene). Initial field testing of lures containing 1, 5 or 10 mg of C19 triene (>98% purity) caught no or very few male M. privata. (3Z,6Z,9Z)-3,6,9-Henicosatriene (C21 triene) was identified as an additional minor pheromone component in abdominal tip extracts of M. privata females from Tasmania. Levels of C19 and C21 trienes extracted from individual females varied greatly, but the ratio was relatively constant at 33:1. Electroantennograms (EAG) of synthetic C21 triene with male M. privata gave positive but consistently lower responses than elicited by the C19 triene. Field tests showed that the addition of 1-6% C21 triene to 1mg C19 triene significantly increased trap catch and the detection of M. privata in plantations. Traps baited with a 16:1 ratio caught significantly more moths than those baited with a ratio approximating that of females.
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| 3. |
- Andersson, Fredrik N G, et al.
(author)
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Preparing for the next crisis: Lessons from the successful Swedish fiscal framework
- 2021
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In: Public debt sustainability: International perspectives. - 9781666902563 ; , s. 69-101
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Book chapter (peer-reviewed)abstract
- Ever since the international financial crisis of 2007/08, Sweden stands out as a country with a prudent and sustainable national debt policy. Debt rises during recessions and crises only to fall back during times of growth. A low debt level before a major crisis allows Sweden to increase its public debt and support the economy during a crisis without risking a fiscal crisis. The strength of the Swedish public finances raises three questions: First, what are the determinants behind this strong performance; second, is the framework sustainable for the future; and third, are there any lessons for other countries?
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| 4. |
- Andersson, Fredrik W., et al.
(author)
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AGI-data ger nya analysmöjligheter av arbetsmarknaden
- 2021
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In: Sveriges ekonomi : statistiskt perspektiv. - : Statististiska Centralbyrån (SCB). - 1653-3828. ; :3, s. 17-21
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Journal article (other academic/artistic)abstract
- AGI-data ger nya analysmöjligheter av arbetsmarknaden. Med hjälp av den nya datakällan AGI kan man studera pandemins effekter på arbetsmarknaden på ett nytt sätt. En grupp som varit särskilt drabbad är den icke folkbokförda befolkningen. Analysen visar också att fyra av fem försvunna jobb i maj 2020 tillhörde låglönesegmentet.
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| 5. |
- Andersson, Fredrik W, et al.
(author)
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Anställda i Sverige under 2021– det andra året med covid-19
- 2022
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In: Ekonomisk Debatt. - 0345-2646. ; 50:6, s. 40-48
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Journal article (pop. science, debate, etc.)abstract
- Vi redovisade i en tidigare artikel utvecklingen av antalet anställda och deras sammansättning under 2020 i Sverige, det första året med covid-19 (Andersson och Wadensjö 2022). Vi kan nu redovisa hur det gick under 2021, det andra året med covid-19. Vi ska först kort redovisa huvudresultaten avseende 2020, för att därefter redovisa resultaten för 2021.
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| 6. |
- Andersson, Fredrik W., 1974-, et al.
(author)
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Ballooning bureaucracy? Stylized facts of growing administration in Swedish higher education
- 2024
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In: Constitutional Political Economy. - : Springer. - 1043-4062 .- 1572-9966. ; 35, s. 303-326
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Journal article (peer-reviewed)abstract
- All organizations need to allocate labor to production and administration. In many cases—particularly within the public sector—the optimal allocation is far from obvious. Indeed, vocal concerns have been raised about the administrative burden in several public services, not least in education. We investigate this issue using detailed registry data on all employees at Swedish universities and colleges from 2005 to 2019 and document three stylized facts. First, the group of highly educated administrators has grown rapidly, almost by a factor of seven compared with teachers and researchers. Second, the number of less-educated administrators has stayed flat. Third, the time that teachers and researchers spend on administrative tasks has been roughly constant over time. This indicates that resources have been diverted from teaching and research and raises fears of excessive administrative growth in Swedish higher education.
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| 7. |
- Andersson, Fredrik W., 1974
(author)
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Consumption Theory with Reference Dependent Utility
- 2006
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Reports (other academic/artistic)abstract
- This paper presents a closed form consumption function for an individual when he derives utility from both his current and previous consumption and from the consumption of his relevant others. I show that the traditional definition of an individual's marginal propensity to consume (MPC) is too narrow. With existing knowledge we would call for a broader definition of the MPC that I coin as the individual's total MPC, which also takes into account the consumption change of the relevant others, and this affects that total MPC is smaller than the traditional MPC
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| 8. |
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| 9. |
- Andersson, Fredrik W., et al.
(author)
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Covid-19 and the Swedish labor market – a register perspective
- 2022
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Reports (other academic/artistic)abstract
- The pandemic has mainly affected the state of health and mortality, but has also had effects on the economy and the labor market. This article reports what happened to the total number of employees, their distribution by sectors and regions and changes in the number of employees for different groups in 2020 compared with 2019 in Sweden. We do not deal with the development of the number and composition of the self-employed. We also do not go into the development of employees' conditions in terms of wages, working hours and working environment. But we are studying something that is in focus for the general debate: How was the development of the number of employees and their composition in 2020, "the first year of the pandemic"? The main result is that we find large differences in the development for different groups.
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| 10. |
- Andersson, Fredrik W., et al.
(author)
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Covid-19 och den svenska arbets-marknaden – ett registerperspektiv
- 2022
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In: Ekonomisk Debatt. - Stockholm, Sverige. - 0345-2646. ; 50:1, s. 7-22
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Journal article (other academic/artistic)abstract
- Pandemin har främstpåverkat hälsotillståndet och dödligheten men ocksåhaft effekter på ekonomin och arbetsmarknaden. I denna artikel redovisasvad som hände med det totala antalet anställda, deras fördelning på sektorer och regioner och förändringar i antalet anställningar för olika grupper2020 jämfört med 2019. Vi behandlar inte utvecklingen av antalet ochsammansättningen av egenföretagarna. Vi går inte heller in på utvecklingen av de anställdas villkor vad gäller löner, arbetstider och arbetsmiljö.Men vi studerar något som är i fokus för den allmänna debatten: Hur varutvecklingen av antalet anställda och deras sammansättning under 2020,”pandemins år”?
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