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- Fu, Michael, 1963, et al.
(författare)
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Optimizing the Management of Heart Failure with Preserved Ejection Fraction in the Elderly by Targeting Comorbidities (OPTIMIZE-HFPEF).
- 2016
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Ingår i: Journal of cardiac failure. - : Elsevier BV. - 1532-8414 .- 1071-9164. ; 22:7, s. 539-544
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Tidskriftsartikel (refereegranskat)abstract
- The pathophysiology of heart failure with preserved ejection fraction (HFPEF) is not fully understood. A recently proposed mechanism for HFPEF is that it is a systemic pro-inflammatory state induced by comorbidities, leading to microvascular endothelial dysfunction and subsequent cardiac remodelling and dysfunction. We hypothesize that targeting comorbidities will improve outcomes in elderly patients with HFPEF. Thus, the aim of this study is to determine whether the combination of systematic screening of patients with HFPEF and optimal management of comorbidities associated with HFPEF improves outcomes.
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- Kähäri, Anders, et al.
(författare)
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Assessment of left ventricular function from M-mode measurement of circumflex artery motion recorded by coronary angiography.
- 2003
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Ingår i: Scandinavian Cardiovascular Journal. - : Informa Healthcare. - 1401-7431 .- 1651-2006. ; 37:5, s. 259-265
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: To evaluate the usefulness of M-mode measurement of circumflex artery motion (CAM) for assessment of left ventricular (LV) function.DESIGN: Seventy-two patients referred for coronary angiography and LV angiography were included. Ejection fraction (EF) was calculated from LV angiography and systolic and diastolic parameters of CAM were measured by M-mode from coronary angiography. Twenty-three patients, examined by echocardiography of mitral annulus motion (MAM) within 24 h before the angiographic examination, formed a subgroup for comparison between angiographic M-mode of CAM and echocardiographic M-mode of MAM.RESULTS: In addition to previous reported CAM amplitude and longitudinal fractional shortening (FSL) the maximal systolic velocity of CAM can be reliably recorded by M-mode. The diastolic indices, atrial contribution to the total amplitude and maximal early and late diastolic velocities, are also well monitored by M-mode of CAM in comparison with echocardiographic MAM.CONCLUSION: LV systolic and diastolic function can be assessed by M-mode of CAM.
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- Kähäri, Anders, et al.
(författare)
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Circumflex artery motion : a new angiographic method for assessment of left ventricular function
- 2003
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Ingår i: Scandinavian Cardiovascular Journal. - Oslo, Norway : Taylor & Francis. - 1401-7431 .- 1651-2006. ; 37:2, s. 80-86
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: To evaluate the usefulness of circumflex artery motion (CAM) for assessment of left ventricular (LV) function.DESIGN: Seventy-three consecutive patients referred for coronary angiography and LV angiography were included. Ejection fraction (EF) was calculated from LV angiography and CAM was measured from coronary angiography.RESULTS: The ratio between CAM and the end-diastolic length of the ventricle, which can be denominated long-axis fractional shortening (FS(L)), was found to be a better index of LV function than CAM per se. There was a significant linear correlation between EF and FS(L) (r = 0.81, SEE = 8.2, p < 0.001). When values of FS(L) > or =10% were selected to define a normal EF (> or =50%) there was a sensitivity of 95% and a specificity of 93%. Visual estimation of EF from CAM was not as good as the use of calculated FS(L) but may me useful as a fast screening method.CONCLUSION: LV systolic function can be assessed by studying CAM recorded by coronary angiography.
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Processrättsliga studier tillägnade Bengt Lindell
- 2021
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- Bengt Lindell kan hösten 2021 se tillbaka på en period av över trettio år som professor i processrätt vid Juridiska fakulteten i Uppsala. Sedan några år är han samtidigt verksam i samma kapacitet vid Karlstads universitet. När Bengt nu närmar sig tidpunkten för pensionsavgång har en grupp vänner och kollegor valt att hedra honom med en festskrift.
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