| 1. |
- Andersen, Zorana J., et al.
(author)
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Long-term Exposure to Ambient Air Pollution and Incidence of Brain Tumor : the European Study of Cohorts for Air Pollution Effects (ESCAPE)
- 2018
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In: Neuro-Oncology. - : Oxford University Press. - 1522-8517 .- 1523-5866. ; 20:3, s. 420-432
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Journal article (peer-reviewed)abstract
- Background: Epidemiological evidence on the association between ambient air pollution and brain tumor risk is sparse and inconsistent.Methods: In 12 cohorts from 6 European countries, individual estimates of annual mean air pollution levels at the baseline residence were estimated by standardized land-use regression models developed within the ESCAPE and TRANSPHORM projects: particulate matter (PM) ≤2.5, ≤10, and 2.5–10 μm in diameter (PM2.5, PM10, and PMcoarse), PM2.5 absorbance, nitrogen oxides (NO2 and NOx) and elemental composition of PM. We estimated cohort-specific associations of air pollutant concentrations and traffic intensity with total, malignant, and nonmalignant brain tumor, in separate Cox regression models, adjusting for risk factors, and pooled cohort-specific estimates using random-effects meta-analyses.Results: Of 282194 subjects from 12 cohorts, 466 developed malignant brain tumors during 12 years of follow-up. Six of the cohorts also had data on nonmalignant brain tumor, where among 106786 subjects, 366 developed brain tumor: 176 nonmalignant and 190 malignant. We found a positive, statistically nonsignificant association between malignant brain tumor and PM2.5 absorbance (hazard ratio and 95% CI: 1.67; 0.89–3.14 per 10–5/m3), and weak positive or null associations with the other pollutants. Hazard ratio for PM2.5 absorbance (1.01; 0.38–2.71 per 10–5/m3) and all other pollutants were lower for nonmalignant than for malignant brain tumors.Conclusion: We found suggestive evidence of an association between long-term exposure to PM2.5 absorbance indicating traffic-related air pollution and malignant brain tumors, and no association with overall or nonmalignant brain tumors.
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| 2. |
- Aslak, Ulf, et al.
(author)
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Constrained information flows in temporal networks reveal intermittent communities
- 2018
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In: Physical review. E. - : American Physical Society. - 2470-0045 .- 2470-0053. ; 97:6
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Journal article (peer-reviewed)abstract
- Many real-world networks represent dynamic systems with interactions that change over time, often in uncoordinated ways and at irregular intervals. For example, university students connect in intermittent groups that repeatedly form and dissolve based on multiple factors, including their lectures, interests, and friends. Such dynamic systems can be represented as multilayer networkswhere each layer represents a snapshot of the temporal network. In this representation, it is crucial that the links between layers accurately capture real dependencies between those layers. Often, however, these dependencies are unknown. Therefore, current methods connect layers based on simplistic assumptions that do not capture node-level layer dependencies. For example, connecting every node to itself in other layers with the same weight can wipe out dependencies between intermittent groups, making it difficult or even impossible to identify them. In this paper, we present a principled approach to estimating node-level layer dependencies based on the network structure within each layer. We implement our node-level coupling method in the community detection framework Infomap and demonstrate its performance compared to current methods on synthetic and real temporal networks. We show that our approach more effectively constrains information inside multilayer communities so that Infomap can better recover planted groups in multilayer benchmark networks that represent multiple modeswith different groups and better identify intermittent communities in real temporal contact networks. These results suggest that node-level layer coupling can improve the modeling of information spreading in temporal networks and better capture intermittent community structure.
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| 3. |
- Stridbeck, Ulf, et al.
(author)
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Vurdering av filleristing av barn i straffesaker for norske domstoler
- 2020
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In: Tidsskrift for rettsvitenskap. - : Scandinavian University Press / Universitetsforlaget AS. - 0040-7143 .- 1504-3096. ; 133:4, s. 423-475
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Journal article (peer-reviewed)abstract
- Dette er en flerfaglig gjennomgang av samtlige norske straffesaker funnet på Lovdata fra 2004 fram til 2015 om «filleristing». Hver sak er gjennomgått av forfatterne; to jurister og tre medisinske eksperter på hodeskader hos barn. Materialet har bestått av straffesaksdokumentene, inkludert sakkyndige rapporter og aktuelle pasientjournaler med billeddiagnostikk av de samme barna. Rettssakene presenteres ut fra dommene, og i de aktuelle sakene er rettens vurderinger i mange saker knyttet opp mot de rettssakkyndiges vurderinger. Parallelt har de medisinske forfatterne etterprøvd hvorvidt de sakkyndiges vurderinger står seg ut fra dagens kunnskap om slike skadebilder. Særlig vekt er lagt på muligheten for at skadebildet ikke er påført ved foreldres eller andres voldsbruk, men av medisinske tilstander hos barnet selv. Det kan synes som om det er få fellende straffedommer som utelukkende er basert på sakkyndighetsvurderinger vedrørende filleristing. I flere andre saker synes det å foreligge tvil når det gjelder skadeårsak og skadepåføring. I tillegg presenteres enkelte barnevernssaker med vekt på beviskravet ved filleristing sammenliknet med straffesakene, men her uten å ha foretatt nye medisinske vurderinger.
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| 4. |
- Wester, Knut, et al.
(author)
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Re-evaluation of medical findings in alleged shaken baby syndrome and abusive head trauma in Norwegian courts fails to support abuse diagnoses
- 2022
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In: Acta Paediatrica. - : John Wiley & Sons. - 0803-5253 .- 1651-2227. ; 111:4, s. 779-792
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Journal article (peer-reviewed)abstract
- AIM: The criteria for diagnosing abusive head trauma (AHT) are not well defined and this condition might be diagnosed on failing premises. Our aim was to review criminal AHT cases in Norwegian courts by scrutinising the underlying medical documentation.METHODS: Cases were identified in the data registry for Norwegian courts from 2004 to 2015. Documentation was obtained from relevant health institutions. The medical co-authors first made independent evaluations of the documentation for each child, followed by a consensus evaluation.RESULTS: A total of 17 children (11 boys) were identified, all diagnosed as AHT by court appointed experts, 15 were infants (mean age 2.6 months). A high proportion (41.2%) was born to immigrant parents and 31.3% were premature. The medical findings could be explained by alternative diagnoses in 16 of the 17 children; 8 boys (7 infants - mean age 2.9 months) had clinical and radiological characteristics compatible with external hydrocephalus complicated by chronic subdural haematoma. Six children (five infants with mean age 2.1 months) had a female preponderance and findings compatible with hypoxic ischaemic insults.CONCLUSION: The medical condition in most children had not necessarily been caused by shaking or direct impact, as was originally concluded by the court experts.
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