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Träfflista för sökning "WFRF:(Asokan T.) "

Search: WFRF:(Asokan T.)

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1.
  • Nagaraja, Ch., et al. (author)
  • Opening remarks
  • 2016
  • Conference paper (peer-reviewed)
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2.
  • Mestre, Humberto, et al. (author)
  • Aquaporin-4-dependent glymphatic solute transport in the rodent brain
  • 2018
  • In: eLife. - 2050-084X. ; 7
  • Journal article (peer-reviewed)abstract
    • The glymphatic system is a brain-wide clearance pathway; its impairment contributes to the accumulation of amyloid-β. Influx of cerebrospinal fluid (CSF) depends upon the expression and perivascular localization of the astroglial water channel aquaporin-4 (AQP4). Prompted by a recent failure to find an effect of Aqp4 knock-out (KO) on CSF and interstitial fluid (ISF) tracer transport, five groups re-examined the importance of AQP4 in glymphatic transport. We concur that CSF influx is higher in wild-type mice than in four different Aqp4 KO lines and in one line that lacks perivascular AQP4 (Snta1 KO). Meta-analysis of all studies demonstrated a significant decrease in tracer transport in KO mice and rats compared to controls. Meta-regression indicated that anesthesia, age, and tracer delivery explain the opposing results. We also report that intrastriatal injections suppress glymphatic function. This validates the role of AQP4 and shows that glymphatic studies must avoid the use of invasive procedures.
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4.
  • Sand, Tommy, 1982, et al. (author)
  • Exploring the Effect of Silicon on the High Temperature Corrosion of Lean FeCrAl Alloys in Humid Air
  • 2021
  • In: Oxidation of Metals. - : Springer Science and Business Media LLC. - 1573-4889 .- 0030-770X. ; 95:3-4, s. 221-238
  • Journal article (peer-reviewed)abstract
    • A new approach to reduce the chromium and aluminium concentrations in FeCrAl alloys without significantly impairing corrosion resistance is to alloy with 1-2 wt.% silicon. This paper investigates the "silicon effect" on oxidation by comparing the oxidation behavior and scale microstructure of two FeCrAl alloys, one alloyed with silicon and the other not, in dry and wet air at 600 degrees C and 800 degrees C. Both alloys formed thin protective oxide scales and the Cr-evaporation rates were small. In wet air at 800 degrees C the Si-alloyed FeCrAl formed an oxide scale containing mullite and tridymite together with alpha- and gamma-alumina. It is suggested that the reported improvement of the corrosion resistance of Al- and Cr-lean FeCrAl's by silicon alloying is caused by the appearance of Si-rich phases in the scale.
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