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- Postmus, Iris, et al.
(author)
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Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins.
- 2014
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In: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 5
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Journal article (peer-reviewed)abstract
- Statins effectively lower LDL cholesterol levels in large studies and the observed interindividual response variability may be partially explained by genetic variation. Here we perform a pharmacogenetic meta-analysis of genome-wide association studies (GWAS) in studies addressing the LDL cholesterol response to statins, including up to 18,596 statin-treated subjects. We validate the most promising signals in a further 22,318 statin recipients and identify two loci, SORT1/CELSR2/PSRC1 and SLCO1B1, not previously identified in GWAS. Moreover, we confirm the previously described associations with APOE and LPA. Our findings advance the understanding of the pharmacogenetic architecture of statin response.
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- Almahfali, Mohammed, et al.
(author)
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Human Rights from an Islamic Perspective : A Critical Review of Arabic Peer-Reviewed Articles
- 2023
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In: Social Sciences. - : MDPI. - 2076-0760. ; 12:2
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Research review (peer-reviewed)abstract
- The relationship between human rights and Islam is important in countries of the Arab world where religion plays a significant role in public debates and daily life. The topic is particularly relevant at a time of sharpening conflicts and polarization, when forms of government in the region, the current world order, and the legitimacy of international organizations are increasingly contested. Much of the scholarly work published in English on this topic draws on sources available in English. This review, therefore, aims to make a contribution to the field through analysis and discussion of academic papers published in Arabic. A search was made in Google Scholar in April 2022 which yielded 12 publications published in 2020 and 2021, after inclusion and exclusion criteria had been applied. These publications were analyzed drawing on the four framing categories. A summary is also given of the definitions, sources, and premises on which the arguments of the publications draw. The reviewed papers contrast the universal and divine foundation of Islamic human rights with the limitations of modern conceptualizations based on the Universal Declaration of Human Rights (UDHR). The latter is described as emanating from Western hegemonistic aspirations and as detached from moral and spiritual values. The papers consequently argue that human rights would be guaranteed globally by generalizing a system of governance based on Shari'a law and the ideal of the Rightly Guided Caliphs. Little attention is given to human rights abuses observed in Muslim societies, diverse interpretations of Islamic source texts, or concrete measures to improve human rights protections in practice. Importantly, the arguments presented in these papers tend to reinforce a contemporary discourse that frames conflicting visions on human rights as a 'clash of civilisations' between 'Islam' and 'the West'.
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- Arrueta, José Antonio, et al.
(author)
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Education reform in Bolivia : Transitions toward which future?
- 2012
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In: Research in Comparative and International Education. - Oxford : SAGE Publications. - 1745-4999. ; 7:4, s. 419-433
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Journal article (peer-reviewed)abstract
- This article concerns the impact of educational reforms on young people in Bolivian society as they transition into adulthood, against the backdrop of globalisation and far-reaching structural changes. Ethnicity and cultural capital are linked in complex ways with social stratification in Bolivia. In a pluricultural society, the language of instruction and curricular content are among the most fundamental conditions that determine which social or linguistic groups will be excluded or disadvantaged during formal education. Language and content are particularly significant in identity formation and in the shaping of cultural capital. Each contributes to the formation of specific intercultural skills and opportunities for communication within national or international communities. Additionally, each of these components helps determine which educational paths are open for young people, and which activities they can engage with later in life. In Bolivia, various education reforms have attempted to reshape these parameters. Intercultural Bilingual Education and other key aspects of the reforms will be described along with the historical context in which they emerged. Some conclusions are put forward related to their implementation.
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- Askerlund, Per, et al.
(author)
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The Nordic forest garden : An educational opportunity for learning about ecological and emotional relationships between organisms
- 2014
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In: Education for sustainable development.
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Conference paper (peer-reviewed)abstract
- Ecosystem services as a perspective on ecological processes is highlighted in the new curriculum for Biology in years 4-9 in Sweden. The ecosystem service-approach implies an anthropocentric perspective in education and an unidirectional view on the purpose and value of other organisms than humans. This study is part of a larger project exploring an educational situation in which 27 seven to eight year-olds participate in creating mini-projects in a forest garden in order to strengthen ecosystem services such as pollination. A forest garden is an edible polyculture landscape with different layers of vegetation. The forest garden is designed to maximise the yield of useful plants while minimizing the input of energy and resources, human labor included (Crawford, 2009). While planning for and establishing a forest garden there is a need to adapt to specific local conditions. The ground must be prepared in a way that makes best use of the solar energy and waterflow through the area and the plants should be placed so that they promote each another. This demands reflection and knowledge about relationships between different kinds of plants but also about relationships between plants and animals. The aim of this substudy is to describe how the children perceive their own relationships to other organisms, as well as how they perceive the relationships between different other organisms. This is investigated in focus group interviews with seven to eight year-olds. Also field notes, video recordings and photos from the children's visits in the forest garden have been collected. The videos and photos have been used for stimulated re-call (Stough, 2001) in a second focus group interview. The data will be analyzed qualitatively (Patton, 2002). In addition to providing insights about the children's perceptions, the project will give examples of how a Nordic forest garden can be used in an educational context. Preliminary findings show cognitive/emotional/moral/ themes describing how children perceive relationships between organisms.
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- Avery, Helen
(author)
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A Library and School Network in Sweden : Social Literacies and Popular Education
- 2017
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In: Teacher and Librarian Partnerships in Literacy Education in the 21st Century. - Rotterdam : Sense Publishers. - 9789463008976 - 9789463008983 - 9789463008990 ; , s. 45-62
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Book chapter (peer-reviewed)abstract
- The topic of this article is the Commons, an integrated school and public library network in an urban multi-ethnic neighbourhood in southern Sweden. In 2011, the Commons network was awarded a national prize as the best school library in Sweden for its outstanding collaboration with the teachers and its exemplary work in stimulating learning. The study explores ways this library – school partnership contributes to the development of literacy and democratic competencies, allowing children to become active members of their local community.
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