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1.	Kanai, M, et al. (author) 2023 swepub:Mat__t
2.	Kurki, MI, et al. (author) Author Correction: FinnGen provides genetic insights from a well-phenotyped isolated population 2023 In: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 615:7952, s. E19-E19 Journal article (other academic/artistic)
3.	Nievergelt, CM, et al. (author) Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder 2024 In: Nature genetics. - 1546-1718. ; 56:5, s. 792-808 Journal article (peer-reviewed)
4.	Frykler Abazi, L, et al. (author) Implementation of an extracorporeal resuscitation (ECPR) program for out-of-hospital cardiac arrest in Stockholm, Sweden: Feasibility, safety, and outcome 2024 In: Resuscitation plus. - 2666-5204. ; 18, s. 100596- Journal article (peer-reviewed)
5.	Jevnikar, Z., et al. (author) Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation 2019 In: Journal of Allergy and Clinical Immunology. - : Elsevier BV. - 0091-6749 .- 1097-6825. ; 143:2, s. 577-590 Journal article (peer-reviewed)abstract Background: Although several studies link high levels of IL-6 and soluble IL-6 receptor (sIL-6R) to asthma severity and decreased lung function, the role of IL-6 trans-signaling (IL-6TS) in asthmatic patients is unclear. Objective: We sought to explore the association between epithelial IL-6TS pathway activation and molecular and clinical phenotypes in asthmatic patients. Methods: An IL-6TS gene signature obtained from air-liquid interface cultures of human bronchial epithelial cells stimulated with IL-6 and sIL-6R was used to stratify lung epithelial transcriptomic data (Unbiased Biomarkers in Prediction of Respiratory Disease Outcomes [U-BIOPRED] cohorts) by means of hierarchical clustering. IL-6TS-specific protein markers were used to stratify sputum biomarker data (Wessex cohort). Molecular phenotyping was based on transcriptional profiling of epithelial brushings, pathway analysis, and immunohistochemical analysis of bronchial biopsy specimens. Results: Activation of IL-6TS in air-liquid interface cultures reduced epithelial integrity and induced a specific gene signature enriched in genes associated with airway remodeling. The IL-6TS signature identified a subset of patients with IL-6TS-high asthma with increased epithelial expression of IL-6TS-inducible genes in the absence of systemic inflammation. The IL-6TS-high subset had an overrepresentation of frequent exacerbators, blood eosinophilia, and submucosal infiltration of T cells and macrophages. In bronchial brushings Toll-like receptor pathway genes were upregulated, whereas expression of cell junction genes was reduced. Sputum sIL-6R and IL-6 levels correlated with sputum markers of remodeling and innate immune activation, in particular YKL-40, matrix metalloproteinase 3, macrophage inflammatory protein 1 beta, IL-8, and IL-1 beta. Conclusions: Local lung epithelial IL-6TS activation in the absence of type 2 airway inflammation defines a novel subset of asthmatic patients and might drive airway inflammation and epithelial dysfunction in these patients.
6.	Li, DQ, et al. (author) HUMAN SKIN LONG NON-CODING RNA WAKMAR1 REGULATES WOUND HEALING BY ENHANCING KERATINOCYTE MIGRATION 2019 In: WOUND REPAIR AND REGENERATION. - : Elsevier BV. - 1067-1927. ; 139:9, s. S323-S323 Conference paper (other academic/artistic)
7.	Mark, PB, et al. (author) Major cardiovascular events and subsequent risk of kidney failure with replacement therapy: a CKD Prognosis Consortium study 2023 In: European heart journal. - 1522-9645. Journal article (peer-reviewed)
8.	Hasselqvist-Ax, I, et al. (author) The Assessment aand Value of Bystander Cardiopulmonary Resuscitation 2013 Conference paper (peer-reviewed)
9.	Hasselqvist-Ax, I, et al. (author) The Assessment and Value of Bystander Cardio Pulmonary Resuscitation (by-CPR) 2013 In: CIRCULATION. - 0009-7322. ; 128:22 Conference paper (other academic/artistic)
10.	Karlsson, LL, et al. (author) No protective role for hypoxic pulmonary vasoconstriction in severe hypergravity-induced arterial hypoxemia 2011 In: European journal of applied physiology. - : Springer Science and Business Media LLC. - 1439-6327 .- 1439-6319. ; 111:9, s. 2099-2104 Journal article (peer-reviewed)

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Type of publication: journal article (28); conference paper (9); research review (1)

Type of content: peer-reviewed (28); other academic/artistic (10)

Author/Editor: Nordberg, P (8); Hollenberg, J (8); Ringh, M (8); Jonsson, M (6); Svensson, L (5); Lindahl, SGE (4); show more...; Vogel, A. (3); Forsberg, S (3); Claesson, A. (3); Rosenqvist, M (3); Stal, P (3); Li, X. (2); James, A. (2); Olsson, H. (2); Herlitz, J (2); Evans, M. (2); Vaarala, O (2); Ito, S (2); Marks, A (2); Davis, LK (2); Werge, T (2); Lee, JY (2); Viikari, Jorma (2); Sjövall, Katarina (2); Smoller, JW (2); Lindqvist, J (2); Deloukas, Panos (2); Mozaffarian, Dariush (2); Johansson, Ingegerd (2); Ericson, Ulrika (2); Franks, Paul W. (2); Orho-Melander, Marju (2); Renström, Frida (2); Hu, Frank B. (2); Ganna, Andrea (2); Ingelsson, Erik (2); Palotie, A (2); Jee, SH (2); Ostling, J (2); Chen, CY (2); Sonestedt, Emily (2); Landén, NX (2); Fox, C (2); Ripatti, S (2); Sjögren, Per (2); Jevnikar, Z. (2); Daly, MJ (2); Zhou, W. (2); Thompson, WK (2); Kronenberg, F (2); show less...

University: Karolinska Institutet (34); Lund University (5); Uppsala University (4); Umeå University (3); University of Gothenburg (1); Kristianstad University College (1); show more...; Royal Institute of Technology (1); Stockholm University (1); Mälardalen University (1); Örebro University (1); Linköping University (1); Stockholm School of Economics (1); University of Borås (1); show less...

Language: English (39)

Research subject (UKÄ/SCB): Medical and Health Sciences (9); Social Sciences (1)

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