| 1. |
- Dahlblom, Mats, et al.
(author)
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Vertical temperature gradients in apartments with hydronic radiator heating
- 2019
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In: Cold Climate HVAC 2018 : Sustainable Buildings in Cold Climates - Sustainable Buildings in Cold Climates. - Cham : Springer International Publishing. - 9783030006617 - 9783030006624 ; , s. 575-585
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Conference paper (peer-reviewed)abstract
- A vertical temperature stratification normally exists in rooms during the heat-ing season in cold climates. An expression of the gradient in apartments heated by hydronic radiator heating systems with exhaust ventilation has ear-lier been developed assuming a dependency of the outdoor temperature. The expression was used by a public real estate owner when re-calculating meas-ured indoor temperature at 2.1 m above floor to 1.2 m above floor represent-ing the occupancy zone and used for individual metering and billing of space heating cost. To validate the suggested expression temperature measurements have been made at four heights in living rooms in apartments built in the 70’s. The heights includes 0.0, 0.1, 1.1 and 1.7 m above floor. The theoreti-cal expression has been compared to the full-scale measurements and in general the expression overestimates the vertical temperature gradient. The measured gradients are generally very low. The thermal comfort in the aspect of vertical temperature gradient is good for the studied period.
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| 2. |
- Egeler, M. D., et al.
(author)
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Understanding quality of life issues in patients with advanced melanoma: Phase 1 and 2 in the development of the EORTC advanced melanoma module
- 2024
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In: European Journal of Cancer. - : Elsevier. - 0959-8049 .- 1879-0852. ; 207
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Journal article (peer-reviewed)abstract
- Aims: We aimed to develop a European Organization for Research and Treatment of Cancer (EORTC) Quality of Life (QoL) module tailored for patients with advanced (resectable or unresectable stage III/IV) melanoma receiving immune checkpoint inhibitors or targeted therapy. Methods: Following the EORTC QoL Group module development guidelines, we conducted phases 1 and 2 of the development process. In phase 1, we generated a list of health-related (HR)QoL issues through a systematic literature review and semi-structured interviews with healthcare professionals (HCPs) and patients with advanced melanoma. In phase 2, these issues were converted into questionnaire items to create the preliminary module. Results: Phase 1: we retrieved 8006 articles for the literature review, of which 35 were deemed relevant, resulting in 84 HRQoL issues being extracted to create the initial issue list. Semi-structured interviews with 18 HCPs and 28 patients with advanced melanoma resulted in 28 issues being added to the initial issue list. Following EORTC module development criteria, 26 issues were removed, and two issues were added after review by patient advocates. Phase 2: To ensure uniformity and avoid duplication, 16 issues were consolidated into eight items. Additionally, an independent expert contributed one new item, resulting in a preliminary module comprising 80 HRQoL items. Conclusion: We identified a range of HRQoL issues (dry skin, xerostomia, and arthralgia) relevant to patients with stage III/IV melanoma. Future module development phases will refine the questionnaire. Once completed, this module will enable standardized assessment of HRQoL in patients with (locally) advanced melanoma.
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| 5. |
- Wesslau, Hanna, et al.
(author)
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Tumor burden and health-related quality of life in patients with melanoma in-transit metastases
- 2023
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In: Cancers. - : MDPI AG. - 2072-6694. ; 15:1
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Journal article (peer-reviewed)abstract
- Background: Few studies have investigated the health-related quality of life (HRQOL) in patients with melanoma in-transit metastases (ITM). The aim was to investigate the association between tumor burden and HRQOL, including disparities pertaining to sex and age, in treatment-naïve patients with ITM. Methods: Functional Assessment of Cancer Therapy-Melanoma (FACT-M) questionnaire was used to assess HRQOL Pairwise comparisons using t-tests between clinical cutoffs are presented and multiple linear regression analysis showing the unique associations of gender, age, number of tumors, tumor size, presence of lymph node metastases, and tumor localization. Results: A total of 95 patients, 47% females and 53% males (median age 72 years) were included between 2012 and 2021. Women scored significantly lower on emotional well-being (p = 0.038) and lower on FACT-M (p = 0.058). Patients who had ≥10 tumors scored significantly lower on FACT-M (p = 0.015), emotional- and functional well-being (p = 0.04, p = 0.004, respectively), melanoma scale (p = 0.005), and FACT-G (p = 0.027). There was no significant difference in HRQOL depending on age, size of tumors, localization, or presence of lymph node metastases. Conclusion: For patients with melanoma ITMs, the female sex and higher tumor burden (i.e., number of tumors) were significantly correlated with lower HRQOL. However, these findings do not fully explain HRQOL for this patient population, and future research should consider the possibility that there are specific questions for patients with ITM where current instruments might fail to measure their discomfort to the full extent.
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| 6. |
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| 7. |
- Arfvidsson, Jesper, et al.
(author)
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Tätskikt i våtrum
- 2005
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Reports (other academic/artistic)
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| 8. |
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| 9. |
- Bagge, Lars
(author)
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Installation av Light Rail i Uppsala : GIS-baserad kollektivtrafikmodell
- 2000
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Reports (other academic/artistic)abstract
- Rapporten redovisar resultaten från en förstudie vars huvudsyften är att, med stöd av GIS, planera en installation av ett kollektivtrafiksystem med applikation på en befintlig urban yta.- Dimensionera kollektivtrafiksystemet utifrån bebyggelsemönster och trafikgenerering.- Utveckla koncept för fordon (uttryckta som kravspecifikationer) och infrastruktur, som möjliggöreffektiv och attraktiv linjedragning och trafikföring i förhållande till bebyggelsestrukturerna.
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