| 1. |
|
|
| 2. |
- Abreu, P, et al.
(författare)
-
Measurement of the spin density matrix for the rho(0), K*(0)(892) and phi produced in Z(0) decays
- 1997
-
Ingår i: PHYSICS LETTERS B. - : ELSEVIER SCIENCE BV. - 0370-2693. ; 406:3, s. 271-286
-
Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- The spin density matrix elements for the rho(0), K-*0(892) and phi produced in hadronic Z(0) decays are measured in the DELPHI detector. There is no evidence for spin alignment of the K-*0(892) and phi, in the region x(p) less than or equal to 0.3 (x(p) =
|
|
| 3. |
- Adori, Csaba, et al.
(författare)
-
Disorganization and degeneration of liver sympathetic innervations in nonalcoholic fatty liver disease revealed by 3D imaging
- 2021
-
Ingår i: Science Advances. - : American Association for the Advancement of Science (AAAS). - 2375-2548. ; 7:30
-
Tidskriftsartikel (refereegranskat)abstract
- Hepatic nerves have a complex role in synchronizing liver metabolism. Here, we used three-dimensional (3D) immunoimaging to explore the integrity of the hepatic nervous system in experimental and human nonalcoholic fatty liver disease (NAFLD). We demonstrate parallel signs of mild degeneration and axonal sprouting of sympathetic innervations in early stages of experimental NAFLD and a collapse of sympathetic arborization in steatohepatitis. Human fatty livers display a similar pattern of sympathetic nerve degeneration, correlating with the severity of NAFLD pathology. We show that chronic sympathetic hyperexcitation is a key factor in the axonal degeneration, here genetically phenocopied in mice deficient of the Rac-1 activator Vav3. In experimental steatohepatitis, 3D imaging reveals a severe portal vein contraction, spatially correlated with the extension of the remaining nerves around the portal vein, enlightening a potential intrahepatic neuronal mechanism of portal hypertension. These fundamental alterations in liver innervation and vasculature uncover previously unidentified neuronal components in NAFLD pathomechanisms.
|
|
| 4. |
|
|
| 5. |
- Alakangas, Lena, et al.
(författare)
-
Norrbottens malm- och mineralresurs och dess potentiella betydelse för innovation, samhälle och miljö
- 2014
-
Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Gruvindustrins betydelse för samhällsutveckling och infrastruktur i Sverige och inte minst i Norrbottens län är mycket stor. De geologiska förutsättningarna att hitta nya brytvärda förekomster i Norrbotten är goda. Länet är tillsammans med Västerbotten en av Europas viktigaste regioner för utvinning av metaller. Det syns också i den nyligen framtagna regionala mineralstrategin för Norrbotten och Västerbotten. Visionen för den regionala mineralstrategin: ”Genom långsiktigt hållbart nyttjande av Norrbottens och Västerbottens läns mineralresurser har ytterligare tillväxt skapats i regionen och hela Sverige. Vi har utvecklat och stärkt vår ställning som ledande gruv- och mineralnation.”Eftersom framtidspotentialen för gruvnäringen är mycket god men okunnigheten hos både allmänhet och beslutsfattare om näringens betydelse för innovation och samhällsutveckling är stor, kopplat med en utbredd oro för miljöpåverkan, måste dessa viktiga framtidsfrågor belysas. Med finansiering från Länsstyrelsen i Norrbotten bedrevs därför under första hälften av 2014 en förstudie som syftade till att sammanfatta kunskapsläget om framtidens gruvindustri i Norrbotten. Resultaten av förstudien redovisas i den här rapporten. En viktig slutsats är att det under nästa strukturfondsperiod (med start 2015) behövs ett framtidsinriktat forskningsprogram för att belysa de möjligheter som finns. Denna förstudie utgör grund för en kommande ansökan till strukturfonderna. Kompetensen som finns vid Luleå tekniska universitet, Sveriges centrum för gruvrelaterad forskning och utbildning, bör användas för att studera troliga framtidsmöjligheter och hur de ska kunna användas för att få en så positiv utveckling som möjligt för länet. Projektet bör innehålla följande tre huvudinriktningar, som naturligtvis hör ihop:Vilka malm- och mineralresurser finns det potential för i Norrbotten, och vilka kommer sannolikt att exploateras i framtiden?Vad kommer den exploateringen att ha för betydelse för innovation och samhällsutveckling?Vad kommer den exploateringen att få för miljöeffekter och hur ska man göra för att minska miljöbelastningen?En annan slutsats är att nedlagda gruvområden inte måste ses som förstörd natur. Betydande mervärden som gruvturism skulle kunna skapas om vilja, kreativitet och beslutsamhet finns. Detta är ett givet utvecklingsområde där småföretag och entreprenörer kan göra stor insats om de politiska och myndighetsmässiga förutsättningarna finns. Dessa aspekter skulle också kunna belysas i det föreslagna forskningsprogrammet eller i ett eget projekt.
|
|
| 6. |
- Albers, Eva, 1966, et al.
(författare)
-
Cellular response in fresh water microalgae to polluting compounds of flue gas when used as carbon source
- 2012
-
Ingår i: 15th Workshop of International Study Group for Systems Biology (ISGSB), September 25-28, Ameland, The Netherlands.
-
Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Attention has lately been given to the use of microalgae as provider of valuable biomass or as production organism. To be able to use algae in industrial production, especially of biofuels, the cultivation procedures need to be improved in terms of efficiency and minimization of production costs. To reach these goals understanding of both process conditions as well as biological response to such conditions is needed for optimization of algal cultivation. Carbon dioxide, the carbon source during phototrophic growth, should be provided at high levels to result in the high biomass concentrations needed for a feasible production. Suitable high-level sources of CO2 are flue gases from industrial activities, which when used for algal cultivation will be a way of carbon capture reducing CO2 emissions. However, flue gases contain additional components that may affect cellular activity negatively. The aim of this research is to understand the physiological behavior of microalgae in industrial conditions to be able to optimize cellular performance. This initial project was launched to provide basic information about response of several types of microalgae that could grow in fresh water conditions to the main gaseous pollutants in flue gas, NO and SO2. This knowledge would guide the selection for a deeper characterization of effect-response relations and control of metabolism in algae in response to industrial conditions. Ten strains of fresh water species and one marine were selected based on reported fast growth and interesting composition such as high levels of lipids. The algae were screened for growth and cellular composition in cultivations with fresh water mineral medium. Artificially produced flue gas, mimicking effluents of pulp mills, consisting of 15% CO2 with 100 ppm NO and 10 ppm SO2 included for the last period of the cultivations was bubbled into the cultures. All strains tested were able to grow and two Scenedesmus strains, an isolated strain from a nearby lake, Chorella protothecoides and Chlamydomonas reinhardtii exhibited the highest specific growth rates. The highest levels of cellular macromolecules were found in Chlorella emersonii (45% carbohydrates), Nannochloropsis salina and the local isolate (65% proteins), and Botrycoccus braunii (57% lipids). It can be concluded that all strains tested were able to grow in cultures with flue gas as carbon source, also the marine species Nannochloropsis salina, and that the gaseous components decrease pH which needs to be monitored carefully to avoid that large drops in pH inhibit algal growth.
|
|
| 7. |
- Albers, Eva, 1966, et al.
(författare)
-
Influence of flue gas mimicking effluents of paper mills on growth and cellular composition of fresh water species of microalgae
- 2012
-
Ingår i: 9th European Workshop on Biotechnology of Microalgae, 4-5 June, Nuthetal, Germany.
-
Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- To be able to use algae in industrial production, especially of biofuels, the cultivation procedures need to be improved in terms of efficiency and minimization of production costs. One important factor is to reach as high biomass concentrations as possible e.g. by using high levels of carbon dioxide provided by flue gas. The aim of this project was to study the influence of flue gas simulated to mimic effluents of pulp mills on growth and cellular composition of microalgae. Ten strains of fresh water species and one marine were selected based on reported fast growth and interesting composition such as high levels of lipids. The algae were screened in cultivations with fresh water mineral medium and artificially produced flue gas bubbled into the cultures consisting of 15% CO2 with 100 ppm NO and 10 ppm SO2 included for the last period of the cultivations. All strains tested were able to grow and two Scenedesmus strains, an isolated strain from a nearby lake, Chorella protothecoides and Chlamydomonas reinhardtii exhibited the highest specific growth rates. The highest levels of cellular macromolecules were found in Chlorella emersonii (45% of carbohydrates), Nannochloropsis salina and the local isolate (65% of proteins), and Botrycoccus braunii (57% of lipids). It can be concluded that all strains tested were able to grow in cultures with flue gas as carbon source, also the marine species Nannochloropsis salina, and that the gaseous components decrease pH which needs to be monitored carefully to avoid that large drops in pH inhibit algal growth.
|
|
| 8. |
- Ali, Raja Hashim, 1985-, et al.
(författare)
-
VMCMC: a graphical and statistical analysis tool for Markov chain Monte Carlo traces
-
Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
- Motivation: MCMC-based methods are important for Bayesian inference of phylogeny and related parameters. Although being computationally expensive, MCMC yields estimates of posterior distributions that are useful for estimating parameter values and are easy to use in subsequent analysis. There are, however, sometimes practical diculties with MCMC, relating to convergence assessment and determining burn-in, especially in large-scale analyses. Currently, multiple software are required to perform, e.g., convergence, mixing and interactive exploration of both continuous and tree parameters.Results: We have written a software called VMCMC to simplify post-processing of MCMC traces with, for example, automatic burn-in estimation. VMCMC can also be used both as a GUI-based application, supporting interactive exploration, and as a command-line tool suitable for automated pipelines. Availability: VMCMC is available for Java SE 6+ under the New BSD License. Executable jar les, tutorial manual and source code can be downloaded from https://bitbucket.org/rhali/visualmcmc/.
|
|
| 9. |
- Ali, Raja Hashim, et al.
(författare)
-
VMCMC: a graphical and statistical analysis tool for Markov chain Monte Carlo traces
- 2017
-
Ingår i: Bmc Bioinformatics. - : Springer Science and Business Media LLC. - 1471-2105. ; 18
-
Tidskriftsartikel (refereegranskat)abstract
- Background: MCMC-based methods are important for Bayesian inference of phylogeny and related parameters. Although being computationally expensive, MCMC yields estimates of posterior distributions that are useful for estimating parameter values and are easy to use in subsequent analysis. There are, however, sometimes practical difficulties with MCMC, relating to convergence assessment and determining burn-in, especially in large-scale analyses. Currently, multiple software are required to perform, e.g., convergence, mixing and interactive exploration of both continuous and tree parameters. Results: We have written a software called VMCMC to simplify post-processing of MCMC traces with, for example, automatic burn-in estimation. VMCMC can also be used both as a GUI-based application, supporting interactive exploration, and as a command-line tool suitable for automated pipelines. Conclusions: VMCMC is a free software available under the New BSD License. Executable jar files, tutorial manual and source code can be downloaded from https://bitbucket. org/rhali/visualmcmc/.
|
|
| 10. |
- Alvarenga, Rodrigo A.F., et al.
(författare)
-
Towards product-oriented sustainability in the (primary) metal supply sector
- 2019
-
Ingår i: Resources, Conservation and Recycling. - : Elsevier. - 0921-3449 .- 1879-0658. ; 145, s. 40-48
-
Tidskriftsartikel (refereegranskat)abstract
- Consideration of sustainable supply of (primary) metals is increasingly influencing the policy agenda of western societies. Environmental sustainability can be managed from different perspectives, including a site-oriented one (strongly used by the mining sector) and a product-oriented one (as with life cycle assessment). The objectives of this article are to analyse and discuss the differences in these perspectives; to discuss potential benefits to the metal/mining sector of also considering the product-oriented perspective; and to propose ways for a smooth implementation. We made use of literature and expert knowledge, on top of interviews with different stakeholders, to identify why and how these perspectives are (not) used in the metal/mining sector. Moreover, we identified three key concerns related to the implementation of a product-oriented perspective in the sector (e.g., use of unrepresentative life cycle inventory (LCI) datasets for metal-based products) and proposed three corrective actions for all of them (e.g., increase the quantity and quality of LCI). Finally, we discuss how the corrective actions could be implemented in the sector in a smooth way and some potential benefits from its implementation.
|
|
