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Enumeration	Reference	Cover	Find
1.	Kanai, M, et al. (author) 2023 swepub:Mat__t
2.	Niemi, MEK, et al. (author) 2021 swepub:Mat__t
3.	Glasbey, JC, et al. (author) 2021 swepub:Mat__t
4.	Tabiri, S, et al. (author) 2021 swepub:Mat__t
5.	Bravo, L, et al. (author) 2021 swepub:Mat__t
6.	2021 swepub:Mat__t
7.	Adamina, M, et al. (author) The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study 2022 In: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland. - : Wiley. - 1463-1318. ; 24:6, s. 708-726 Journal article (peer-reviewed)
8.	2021 swepub:Mat__t
9.	Iarko, V., et al. (author) Extension of nanoconfined DNA: Quantitative comparison between experiment and theory 2015 In: Physical Review E (Statistical, Nonlinear, and Soft Matter Physics). - 1539-3755 .- 1550-2376. ; 92:6, s. Art. Nr. 062701- Journal article (peer-reviewed)abstract The extension of DNA confined to nanochannels has been studied intensively and in detail. However, quantitative comparisons between experiments and model calculations are difficult because most theoretical predictions involve undetermined prefactors, and because the model parameters (contour length, Kuhn length, effective width) are difficult to compute reliably, leading to substantial uncertainties. Here we use a recent asymptotically exact theory for the DNA extension in the "extended de Gennes regime" that allows us to compare experimental results with theory. For this purpose, we performed experiments measuring the mean DNA extension and its standard deviation while varying the channel geometry, dye intercalation ratio, and ionic strength of the buffer. The experimental results agree very well with theory at high ionic strengths, indicating that the model parameters are reliable. At low ionic strengths, the agreement is less good. We discuss possible reasons. In principle, our approach allows us to measure the Kuhn length and the effective width of a single DNA molecule and more generally of semiflexible polymers in solution.

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Type of publication: journal article (2)

Type of content: peer-reviewed (2)

Author/Editor: Davies, E. (8); Martin, J. (8); Ali, S (8); Smith, L (8); Smith, J. (8); Jones, M. (7); show more...; Williams, G. (7); Jones, R. (7); Khan, A. (7); Thomas, E. (7); Evans, J. (7); Davies, M. (6); Lopes, L. (6); Losada, M. (6); Romano, M. (6); Gupta, A. (6); Aytac, E (6); Davies, RJ (6); Hompes, R (6); Lakkis, Z (6); Shaikh, (6); Tsarkov, P (6); Brown, A. (6); Silva, M. (6); Moore, R. (6); Russ, J. (6); Sharma, N. (6); Singh, R. (6); Nowak, K. (6); Costa, M. (6); Patel, P. (6); Abate, E. (6); Lee, M (6); Ali, M (6); Biondi, A (6); Salem, H (6); Shah, S (6); Desai, A. (6); Young, R. (6); Sharma, P. (6); Abdalla, M. (6); Santos, R. (6); Conti, L. (6); Sherif, A. (6); Bhalla, A (6); Knight, A. (6); Murphy, S. (6); Green, S (6); Pereira, R (6); Khan, T. (6); show less...

University: Karolinska Institutet (6); University of Gothenburg (1); Lund University (1); Chalmers University of Technology (1)

Language: English (9)

Research subject (UKÄ/SCB): Natural sciences (1); Engineering and Technology (1)

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