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Sökning: WFRF:(Bern J)

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1.
  • Kawahara, R., et al. (författare)
  • Community evaluation of glycoproteomics informatics solutions reveals high-performance search strategies for serum glycopeptide analysis
  • 2021
  • Ingår i: Nature Methods. - : Springer Science and Business Media LLC. - 1548-7091 .- 1548-7105. ; 18, s. 1304-1316
  • Tidskriftsartikel (refereegranskat)abstract
    • Glycoproteomics is a powerful yet analytically challenging research tool. Software packages aiding the interpretation of complex glycopeptide tandem mass spectra have appeared, but their relative performance remains untested. Conducted through the HUPO Human Glycoproteomics Initiative, this community study, comprising both developers and users of glycoproteomics software, evaluates solutions for system-wide glycopeptide analysis. The same mass spectrometrybased glycoproteomics datasets from human serum were shared with participants and the relative team performance for N- and O-glycopeptide data analysis was comprehensively established by orthogonal performance tests. Although the results were variable, several high-performance glycoproteomics informatics strategies were identified. Deep analysis of the data revealed key performance-associated search parameters and led to recommendations for improved 'high-coverage' and 'high-accuracy' glycoproteomics search solutions. This study concludes that diverse software packages for comprehensive glycopeptide data analysis exist, points to several high-performance search strategies and specifies key variables that will guide future software developments and assist informatics decision-making in glycoproteomics. This analysis presents the results of a community-based evaluation of existing software for large-scale glycopeptide data analysis.
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2.
  • Bern, Z., et al. (författare)
  • Gravity Amplitudes as Generalized Double Copies of Gauge-Theory Amplitudes
  • 2017
  • Ingår i: Physical Review Letters. - : American Physical Society. - 0031-9007 .- 1079-7114. ; 118:18
  • Tidskriftsartikel (refereegranskat)abstract
    • Whenever the integrand of a gauge-theory loop amplitude can be arranged into a form where the Bern-Carrasco-Johansson duality between color and kinematics is manifest, a corresponding gravity integrand can be obtained simply via the double-copy procedure. However, finding such gauge-theory representations can be challenging, especially at high loop orders. Here, we show that we can, instead, start from generic gauge-theory integrands, where the duality is not manifest, and apply a modified double-copy procedure to obtain gravity integrands that include contact terms generated by violations of dual Jacobi identities. We illustrate this with three-, four- and five-loop examples in N=8 supergravity.
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3.
  • Travaglini, Gabriele, et al. (författare)
  • The SAGEX review on scattering amplitudes
  • 2022
  • Ingår i: Journal of Physics A. - : IOP Publishing. - 1751-8113 .- 1751-8121. ; 55:44
  • Forskningsöversikt (refereegranskat)abstract
    • This is an introduction to, and invitation to read, a series of review articles on scattering amplitudes in gauge theory, gravity, and superstring theory. Our aim is to provide an overview of the field, from basic aspects to a selection of current (2022) research and developments.
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