| 1. |
- Alexanderson, Simon, et al.
(author)
-
Robust online motion capture labeling of finger markers
- 2016
-
In: Proceedings - Motion in Games 2016. - New York, NY, USA : ACM Digital Library. - 9781450345927 ; , s. 7-13
-
Conference paper (peer-reviewed)abstract
- Passive optical motion capture is one of the predominant technologies for capturing high fidelity human skeletal motion, and is a workhorse in a large number of areas such as bio-mechanics, film and video games. While most state-of-the-art systems can automatically identify and track markers on the larger parts of the human body, the markers attached to fingers provide unique challenges and usually require extensive manual cleanup. In this work we present a robust online method for identification and tracking of passive motion capture markers attached to the fingers of the hands. The method is especially suited for large capture volumes and sparse marker sets of 3 to 10 markers per hand. Once trained, our system can automatically initialize and track the markers, and the subject may exit and enter the capture volume at will. By using multiple assignment hypotheses and soft decisions, it can robustly recover from a difficult situation with many simultaneous occlusions and false observations (ghost markers). We evaluate the method on a collection of sparse marker sets commonly used in industry and in the research community. We also compare the results with two of the most widely used motion capture platforms: Motion Analysis Cortex and Vicon Blade. The results show that our method is better at attaining correct marker labels and is especially beneficial for real-time applications.
|
|
| 2. |
- Beskow, Anne, et al.
(author)
-
A conserved unfoldase activity for the p97 AAA-ATPase in proteasomal degradation
- 2009
-
In: Journal of Molecular Biology. - : Elsevier BV. - 0022-2836 .- 1089-8638. ; 394:4, s. 732-46
-
Journal article (peer-reviewed)abstract
- The multifunctional AAA-ATPase p97 is one of the most abundant and conserved proteins in eukaryotic cells. The p97/Npl4/Ufd1 complex dislocates proteins that fail the protein quality control in the endoplasmic reticulum to the cytosol where they are subject to degradation by the ubiquitin/proteasome system. Substrate dislocation depends on the unfoldase activity of p97. Interestingly, p97 is also involved in the degradation of specific soluble proteasome substrates but the exact mode of action of p97 in this process is unclear. Here, we show that both the central pore and ATPase activity of p97 are necessary for the degradation of cytosolic ubiquitin-fusion substrates. Addition of a flexible extended C-terminal peptide to the substrate relieves the requirement for p97. Deletion mapping reveals a conserved length dependency of 20 residues for the peptide, which allows p97-independent degradation to occur. Our results suggest that initiation of unfolding may be more complex than previously anticipated and that the 19S regulatory complex of the proteasome can require preprocessing of highly folded, ubiquitylated substrates by the p97(Ufd1/Npl4) complex. Our data provide an explanation for the observation that p97 is only essential for a subpopulation of soluble substrates and predict that a common characteristic of soluble p97-dependent substrates is the lack of an initiation site to facilitate unfolding by the 26S proteasome.
|
|
| 3. |
|
|
| 4. |
|
|
| 5. |
- Beskow, C, et al.
(author)
-
Expression of DNA damage response proteins and complete remission after radiotherapy of stage IB-IIA of cervical cancer.
- 2006
-
In: British Journal of Cancer. - : Nature Publishing Group. - 0007-0920 .- 1532-1827. ; 94:11, s. 1683-1689
-
Journal article (peer-reviewed)abstract
- The primary aim of this study was to investigate if the expression of the DNA damage identifying protein DNA-PKcs known to be involved in DNA repair after treatment with ionising radiation can be used as a predictive marker for radiotherapy (RT) response in cervical cancer. Formalin-fixed primary tumour biopsies from 109 patients with cervical cancer, FIGO-stage IB-IIA, treated with preoperative brachytherapy followed by radical surgery were analysed by immunohistochemistry. In addition, correlation studies between early pathological tumour response to radiation and expression of Ku86, Ku70, Mdm-2, p53 and p21 in primary tumours were also performed. We found that tumour-transformed tissue shows positive immunostaining of DNA-PKcs, Ku86 and Ku70, while non-neoplastic squamous epithelium and tumour-free cervix glands show negative immunoreactivity. Expression of DNA-PKcs positively correlated with both Ku86 and Ku70, and a statistically significant correlation between the Ku subunits was also found. After RT, 85 patients demonstrated pathologic complete remission (pCR), whereas 24 patients had residual tumour in the surgical specimen (non-pCR). The main finding of our study is that there was no correlation between the outcome of RT and the expression of DNA-PK subunits. Positive p53 tumours were significantly more common among non-pCR cases than in patients with pCR (P=0.031). Expression of p21 and Mdm-2 did not correlate with the outcome of RT.
|
|
| 6. |
- Beskow, C, et al.
(author)
-
Improving Co-operation in project teams
- 1997
-
In: <em>The sixth international conference on management of technology, MOT 1997, </em>Göteborg.
-
Conference paper (peer-reviewed)
|
|
| 7. |
|
|
| 8. |
|
|
| 9. |
- Beskow, Jonas, et al.
(author)
-
Expressive robot performance based on facial motion capture
- 2021
-
In: Proceedings of the Annual Conference of the International Speech Communication Association, INTERSPEECH. - : International Speech Communication Association. ; , s. 2165-2166, s. 2343-2344
-
Conference paper (peer-reviewed)abstract
- The Furhat robot is a social robot that uses facial projection technology to achieve a high degree of expressivity and flexibility. In this demonstration, we will present new features that takes this facial expressiveness further. A new face engine for the robot is presented which not only drastically improves the visual fidelity of the face and the eyes, it also adds increased flexibility when it comes to designing new robotic characters as well as modifying existing ones. Most importantly, we will present a new toolset and a workflow that allows users to record their own face motion and incorporate them into skills (i.e. custom robot applications) as gestures, prompts or entire canned performances.
|
|
| 10. |
- Beskow, Jonas, et al.
(author)
-
Preface
- 2017
-
In: 17th International Conference on Intelligent Virtual Agents, IVA 2017. - : Springer. - 9783319674001 ; , s. V-VI
-
Conference paper (peer-reviewed)
|
|
