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1.	Öhman, Lena, 1967, et al. (author) Regression of Peyer's patches in G alpha i2 deficient mice prior to colitis is associated with reduced expression of Bcl-2 and increased apoptosis. 2002 In: Gut. - 0017-5749. ; 51:3, s. 392-7 Journal article (peer-reviewed)abstract G protein deficient (G alpha i2-/-) mice spontaneously develop an inflammatory bowel disease (IBD) closely resembling ulcerative colitis. Previous studies have demonstrated that gut T cells are hyperreactive to the endogenous microflora in most IBD models.
2.	Uhlig, H H, et al. (author) Antibody response to dietary and autoantigens in G alpha i2-deficient mice. 2001 In: European journal of gastroenterology & hepatology. - 0954-691X. ; 13:12, s. 1421-9 Journal article (peer-reviewed)abstract Mice with a targeted mutation in the G protein subunit G alpha i2 gene develop a colonic mucosal inflammation, with a highly activated B-cell response. We wanted to investigate whether this increased B-cell activity was directed against dietary antigens and/or various self tissues.

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Author/Editor: Öhman, Lena, 1967 (2); Hultgren Hörnquist, ... (2); Rudolph, U (2); Birnbaumer, L (2); Franzen, L (1); Uhlig, H H (1); show more...; Mothes, T (1); show less...

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